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vascular
908 studies tagged vascular, dated 1975-09-01 to 2026-09-14. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Pathway-specific polygenic risk scores reveal underlying mechanisms of cerebral small vessel disease 2026-09-14
- Cerebral Small Vessel Disease and Risk of Cardiovascular Events and All-Cause Mortality: The Framingham Heart Study 2026-09-07
- Regional Distribution of Mineralized Blood Vessels in Alzheimer Disease and Clinicopathological Associations: A Multicenter Autopsy Study 2026-09-01
Studies
908 studies carry this tag.
Date range
1975 to 2026
Top journals
- Neurology 93
- Stroke 61
- Alzheimer s & Dementia 31
- Brain : a journal of neurology 20
- Annals of neurology 19
343 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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While delirium is associated with cognitive decline and dementia, there is limited evidence to support causality for this relationship.
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The 2-year multidomain FINGER intervention may modulate white matter microstructural alterations.
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Differently from other myeloid cells, microglia derive exclusively from precursors originating within the yolk sac and migrate to the CNS under development, without any contribution from fetal liver or postnatal hematopoiesis.
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Individual differences in working memory relate to performance differences in general cognitive ability.
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In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events.
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Astrocytes are a population of cells with distinctive morphological and functional characteristics that differ within specific areas of the brain.
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Advances in human genetics have implicated a growing number of genes in neurodegenerative diseases, providing insight into pathological processes.
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The findings suggest that midlife HI is a risk factor for temporal lobe volume loss.
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Recent interest in enlarged perivascular spaces (ePVS) in the brain, which can be visualized on MRI and appear isointense to cerebrospinal fluid on all sequence weightings, has resulted in the necessity of reliable algorithms for automated segmentation to allow for whole brain assessment of ePVS burden.
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High and increasing blood pressure from early adulthood into midlife seems to be associated with increased WMHV and smaller brain volumes at 69-71 years of age.
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Microglia are resident macrophages of the CNS that are involved in its development, homeostasis and response to infection and damage.
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Current brain spheroids or organoids derived from human induced pluripotent stem cells (hiPSCs) still lack a microglia component, the resident immune cells in the brain.
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Higher levels of VRFs were associated with poorer brain health across grey and white matter macrostructure and microstructure.
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Inflammation is increasingly implicated as a risk factor for dementia, stroke, and small vessel disease (SVD).
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CNS small vessel disease (CSVD) causes 25% of strokes and contributes to 45% of dementia cases.
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Small vessel disease is a disorder of cerebral microvessels that causes white matter hyperintensities and several other common abnormalities (eg, recent small subcortical infarcts and lacunes) seen on brain imaging.
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Cerebral small vessel disease (cSVD) comprises pathological processes of the small vessels in the brain that may manifest clinically as stroke, cognitive impairment, dementia, or gait disturbance.
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55/100
Obesity has been associated with increased risk of accelerated cognitive decline and dementia, which suggests underlying neurobiological changes.
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Features for rule-based systems, including significant words and patterns related to SBI, were generated using pointwise mutual information.
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White matter hyperintensities (WMHs) are frequently seen on brain magnetic resonance imaging scans of older people.
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Dementia risk may be attenuated by physical activity (PA); however, the specific activity levels optimal for dementia prevention are unclear.
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Patients with Alzheimer's Disease (AD) exhibit decreased retinal blood flow and vessel density (VD).
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Our search resulted in the inclusion and full-text review of 137 articles.
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ANOVA revealed significant group differences in lateral ventricular SUVR across the Alzheimer, mild cognitive impairment, and healthy control groups ( P = 0.004).
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Current models of progression in neurodegenerative diseases use neuroimaging measures that are averaged across pre-defined regions of interest (ROIs).
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Hypertension has emerged as a leading cause of age-related cognitive impairment.
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Presence and severity of WMH are associated with substantially increased risk of dementia, functional impairment, stroke recurrence, and mortality after ischemic stroke.
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Mediation analyses proposed that visceral obesity contributes to deep white matter lesions through increases in proinflammatory cytokines, suggesting a pathomechanistic link.
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Aging is regarded as a major risk factor for neurodegenerative diseases.
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In an older cohort with low cerebrovascular disease burden, T2DM contributes to cognitive decline via neurodegeneration.
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Forty-one women who underwent BSO and 49 control participants were recruited.
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Of 2846 articles identified, 94 studies were eligible, with up to 14 529 participants for WMH, 16 012 participants for BI, 15 693 participants for CMB, and 4587 participants for PVS.
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A chronic and gradual increase in pulse pressure (PP) is associated with cognitive decline and dementia in older individuals, but the mechanisms remain ill-defined.
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A diffusion prepared 3D GRASE pCASL sequence with TGV regularized SPA modeling was proposed to measure BBB water permeability noninvasively with good reproducibility. k w may serve as an imaging marker of cerebral SVD and associated cognitive impairment.
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N -acetylcysteine (NAC), which is an acetylated cysteine compound, has aroused scientific interest for decades due to its important medical applications.
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This review recounts the definitions and research evidence supporting the multifaceted roles of neuroinflammation in the injured brain following trauma.
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In the general population, we investigated the association of a recently developed cerebral small vessel disease (CSVD) sum score with stroke, dementia, and mortality.
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41/100
Vascular cognitive impairment (VCI) defines an entire spectrum of neurologic disorders from mild cognitive impairment to dementia caused by cerebral vascular disease.
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Vascular dementia (VaD) is the second most common type of dementia after Alzheimer's disease (AD), characterized by progressive cognitive impairment, memory loss, and thinking or speech problems.
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There is a strong association between PM 2.5 exposure and neurological disorders.
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Since the discovery of CSF1R gene mutations in families with hereditary diffuse leukoencephalopathy with spheroids in 2012, more than 70 different mutations have been identified around the world.
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We evaluated dementia-free Framingham Heart Study (generation 3) participants (mean age 48.5 years, 46.8% men) who underwent cognitive testing for memory, abstract reasoning, visual perception, attention, and executive function (n = 2,231) and brain MRI (n = 2018) to assess total white matter, lobar gray matter, and white matter hyperintensity volumes and fractional anisotropy (FA) measures.
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MoCA was administered to 274 patients from 2 prospective hospital-based cohort studies in Germany (n = 125) and France (n = 149).
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Efficient blood supply to the brain is of paramount importance to its normal functioning and improper blood flow can result in potentially devastating neurological consequences.
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Among participants with normal cognition, higher aortic PWV related to lower frontal lobe CBF (β=-0.43; P=0.04) and higher CVR in the whole brain (β=0.11; P=0.02), frontal lobes (β=0.12; P<0.05), temporal lobes (β=0.11; P=0.02), and occipital lobes (β=0.14; P=0.01).
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Cerebral small vessel disease (CSVD) is composed of several diseases affecting the small arteries, arterioles, venules, and capillaries of the brain, and refers to several pathological processes and etiologies.
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Given the potential therapeutic effect of vascular disease control timing to reduce dementia risk, we investigated the age-related influences of vascular risk factor burden on brain structure throughout the lifespan.
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Small vessel diseases (SVDs) are a group of disorders that result from pathological alteration of the small blood vessels in the brain, including the small arteries, capillaries and veins.
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We tested the hypothesis that BBB breakdown is associated with cognitive decline and inflammation in nondemented elders.
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Diabetes and prediabetes accelerate cognitive decline and might predict microvascular lesions among dementia-free older adults.
From across this tag
10 of the 907 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Homocysteine, silent brain infarcts, and white matter lesions: The Rotterdam Scan Study
- Harmonization Remains Unresolved: The Case of White Matter Hyperintensity Using ComBat And Deming Regression
- Course of cerebral amyloid angiopathy-related inflammation
- Functional roles of microglia in the brain
- Epidemiology of mild traumatic brain injury and neurodegenerative disease
- Slowly progressive aphasia: three cases with language, memory, CT and PET data
- The role of inflammation in cerebral small vessel disease and vascular cognitive impairment, and therapeutic implications
- Associations of White Matter Hyperintensities with Cognitive Decline: A Longitudinal Study
- Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases
- Unrecognized myocardial infarction in relation to risk of dementia and cerebral small vessel disease