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Newest in this topic

  1. Interventions for Cognitive Impairment in Type 2 Diabetes Mellitus: An Umbrella Review of Pharmacological and Lifestyle Strategies, Mechanisms, and Clinical Implications 2026-10-26
  2. Visit-to-Visit Blood Pressure Variability, Glycemic Status and the Risk of Dementia, Stroke, and All-Cause Mortality: A UK Biobank Cohort Study 2026-10-13
  3. Plasma metabolomic profiling of frailty in older adults at risk of dementia 2026-10-08

Studies

304 studies carry this tag.

Date range

1984 to 2026

Top journals

  • Journal of Alzheimer's disease : JAD 21
  • medRxiv 16
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 14
  • Neurology 10
  • Nutrients 10

164 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Long Chain Omega-3 Fatty Acid Intervention in Ageing Adults at Risk of Dementia Following Repeated Head Trauma. Low-level Support or an Opportunity for an Unanswered Question?

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. The journal of prevention of Alzheimer's disease 2021 Prevention and risk

    Emerging evidence of brain injury on risk of neurodegenerative diseases such as Alzheimer's disease (AD) and chronic traumatic encephalopathy (CTE) have resulted in interest in therapeutic potential of omega-3 fatty acids (n-3FA).

  2. Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Current topics in behavioral neurosciences 2021 Risk factors

    Evidence from epidemiological studies on the general population suggests that midlife cardiovascular disease (CVD) and/or metabolic syndrome (MetS) are associated with an increased risk of cognitive impairment and dementia later in life.

  3. Dietary Habits and Risk of Early-Onset Dementia in an Italian Case-Control Study

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Nutrients 2020-11-29 Prevention and risk

    Risk of early-onset dementia (EOD) might be modified by environmental factors and lifestyles, including diet.

  4. Later-Onset Hypertension Is Associated With Higher Risk of Dementia in Mild Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Frontiers in neurology 2020-11-26 Risk factors

    To investigate the correlation between hypertension development and the progression of mild cognitive impairment (MCI) to dementia in middle-aged and elderly people.

  5. Statin therapy and risk of Alzheimer's and age-related neurodegenerative diseases

    ✓ Peer-reviewed alzhub usefulness score 76 out of 100. Alzheimer's & dementia (New York, N. Y.) 2020-11-25 Digital health tools

    Benefits and risks of statins relative to neurological outcomes should be considered when prescribed for at-risk NDD populations.

  6. Is there a relationship between blood pressure values and dementia?

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. European heart journal supplements : journal of the European Society of Cardiology 2020-11-18 Risk factors

    The relationship between arterial hypertension and cognitive decline, two among the conditions with higher prevalence in the elderly population, has gained significant interest, in the scientific community, during the last few years, stemming from the numerous epidemiologic, experimental, and therapeutic evidences suggesting a non-casual correlation between the two conditions.

  7. Cardiovascular Risk Factors, Cognitive Dysfunction, and Mild Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Dementia and geriatric cognitive disorders extra 2020-11-16 Risk factors

    A difference between subjects with and without obesity and memory scores was shown by t tests.

  8. Study design and baseline characteristics of a population-based prospective cohort study of dementia in Japan: the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD)

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Environmental health and preventive medicine 2020-10-31 Biomarkers

    The prospective cohort data from the JPSC-AD will provide valuable insights regarding the risk factors and etiology of dementia as well as for the development of predictive models and diagnostic markers for the future onset of dementia.

  9. Dietary Interventions to Prevent or Delay Alzheimer's Disease: What the Evidence Shows

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Current nutrition reports 2020-09 Prevention and risk

    A variety of potentially modifiable risk factors have been investigated in an attempt to delay/prevent Alzheimer's disease (AD).

  10. Obesity impacts brain metabolism and structure independently of amyloid and tau pathology in healthy elderly

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2020-07-28 Tau biomarkers

    We included 201 individuals (mean age 73.5 years, mean BMI 27.4 kg/m2).

  11. Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials

    ✓ Peer-reviewed alzhub usefulness score 76 out of 100. Journal of neurology, neurosurgery, and psychiatry 2020-07-20 Risk factors

    Evidence-based suggestions are proposed, offering clinicians and stakeholders current guidance for the prevention of AD.

  12. Preventive Role of L-Carnitine and Balanced Diet in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Nutrients 2020-07-03 Prevention and risk

    The prevention or alleviation of neurodegenerative diseases, including Alzheimer's disease (AD), is a challenge for contemporary health services.

  13. Effects of Cardiovascular Risk Factor Variability on Health Outcomes

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Endocrinology and metabolism (Seoul, Korea) 2020-06-24 Risk factors

    Innumerable studies have suggested "the lower, the better" for cardiovascular risk factors, such as body weight, lipid profile, blood pressure, and blood glucose, in terms of health outcomes.

  14. The Role of Nutrition in Individualized Alzheimer's Risk Reduction

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Current nutrition reports 2020-06 Prevention and risk

    RECENT FINDINGS: Specific dietary patterns and varied nutrient combinations can have a protective effect on brain health, promote cognitive function, and mediate the comorbidity of chronic conditions associated with increased AD risk.

  15. Impact of antidiabetic agents on dementia risk: A Bayesian network meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 78 out of 100. Metabolism: clinical and experimental 2020-05-22 Drug development

    This analysis indicated that patients with type 2 diabetes under treatment with DPP-4 inhibitors presented with the lowest risk of dementia, followed by those treated with metformin and thiazolidinedione, while treatment with insulin was associated with the highest risk.

  16. [The cognitive-behavioural impact of hypertension]

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Hipertension y riesgo vascular 2020-05-17 Risk factors

    Arterial hypertension is considered the main modifiable vascular risk factor that causes silent damage to brain vessels.

  17. [Toward a preventive management Alzheimer's disease]

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Bulletin de l'Academie nationale de medecine 2020-04-21 Prevention trials

    Dementias, and Alzheimer's disease (AD) in particular, will increasingly become a public health issue.

  18. Blood Pressure Control and Dementia Risk in Midlife Patients With Atrial Fibrillation

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Hypertension (Dallas, Tex. : 1979) 2020-03-16 Risk factors

    Atrial fibrillation (AF) is associated with increased risk of cognitive impairment and dementia, even with no overt stroke.

  19. Association Between Hormone-Modulating Breast Cancer Therapies and Incidence of Neurodegenerative Outcomes for Women With Breast Cancer

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. JAMA network open 2020-03-02 Digital health tools

    Among patients with breast cancer, tamoxifen and steroidal aromatase inhibitors were associated with a decrease in the number who received a diagnosis of NDD, specifically Alzheimer disease and dementia.

  20. Future Directions for Dementia Risk Reduction and Prevention Research: An International Research Network on Dementia Prevention Consensus

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Journal of Alzheimer's disease : JAD 2020 Prevention trials

    In the past decade a large body of evidence has accumulated on risk factors for dementia, primarily from Europe and North America.

  21. Risk Reduction and Prevention of Alzheimer's Disease: Biological Mechanisms of Diet

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Current Alzheimer research 2020 Prevention and risk

    Alzheimer's Disease (AD) incidence is increasing and with no disease modifying agents available, preventative measures through lifestyle factors are being investigated.

  22. Mid-life and late-life vascular risk factor burden and neuropathology in old age

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Annals of clinical and translational neurology 2019-11-05 Vascular contributions

    The median time interval between FSRP and death was 33.4 years for mid-life FSRP and 4.4 years for final FSRP measurement before death.

  23. Antidiabetic medication and risk of dementia in patients with type 2 diabetes: a nested case-control study

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. European journal of endocrinology 2019-11-01 Drug development

    Use of metformin, DPP4 inhibitors, GLP1 analogs and SGLT2 inhibitors was associated with lower risk of dementia in patients with diabetes.

  24. "A priori" Dietary Patterns and Cognitive Function in the SUN Project

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Neuroepidemiology 2019-10-10 Prevention and risk

    Adjusted differences showed advantages in the 6-year change in STICS-m score of 0.25 (95% CI 0.04-0.45) for an increase of 1-SD (9 points) in the AHEI-2010 and of 0.27 (95% CI 0.05-0.48) for an increase of 1-SD (1.5 points) in the MIND diet.

  25. Pathogenetic pathways of cognitive dysfunction and dementia in metabolic syndrome

    ✓ Peer-reviewed alzhub usefulness score 68 out of 100. Life sciences 2019-10-10 Risk factors

    The prevalence of dementia worldwide is growing at an alarming rate.

  26. Associations between cerebrovascular risk factors and parkinson disease

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Annals of neurology 2019-08-29 Digital health tools

    Cerebrovascular risk factors are associated with Parkinson disease, an effect comparable to their association with Alzheimer disease.

  27. Effect of Linagliptin on Cognitive Performance in Patients With Type 2 Diabetes and Cardiorenal Comorbidities: The CARMELINA Randomized Trial

    ✓ Peer-reviewed alzhub usefulness score 83 out of 100. Diabetes care 2019-08-09 Drug development

    In a large international cardiovascular outcome trial in people with type 2 diabetes and cardiorenal disease, linagliptin did not modulate cognitive decline over 2.5 years.

  28. Apolipoprotein E Genotype Modifies the Association Between Cardiac Output and Cognition in Older Adults

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Journal of the American Heart Association 2019-07-31 Genetics

    APOE-ε4 carrier status appears to modify the cross-sectional association between cardiac output and neuropsychological performance such that lower cardiac output relates to poorer performances among carriers of the ε4 allele.

  29. Effects of Anserine/Carnosine Supplementation on Mild Cognitive Impairment with APOE4

    ✓ Peer-reviewed alzhub usefulness score 73 out of 100. Nutrients 2019-07-17 Clinical trials

    The score improvement in the global Clinical Dementia Rating (gloCDR) was superior in the active group than placebo (p = 0.023).

  30. Association Between Relevant Co-Morbidities and Dementia With Atrial Fibrillation-A National Study

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Archives of medical research 2019-05-31 Risk factors

    Totally 30,332 patients (5.6%) were diagnosed with dementia during the follow-up, with 14,097 men (4.9%) and 16,235 women (6.5%).

  31. The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 81 out of 100. Clinical epigenetics 2019-04-11 Genetics

    Due to the small number of studies and heterogeneity in study design and outcomes, the association between DNA methylation age and age-related disease and longevity is inconclusive.

  32. Associations of the metabolic syndrome and its components with cognitive impairment in older adults

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. BMC geriatrics 2019-03-07 Risk factors

    Lower HDL-C was significantly associated with a higher odds of cognitive impairment (OR 2.70 per 1 mmol/L reduction; 95% CI 1.25, 5.56; p = 0.011), whereas BMI, TG, glucose and HbA1c were not (all p > 0.05).

  33. Atrial Fibrillation and Risk of Dementia: Epidemiology, Mechanisms, and Effect of Anticoagulation

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Frontiers in neuroscience 2019-01-31 Risk factors

    Atrial fibrillation (AF) is one of the cardiovascular risk factors for dementia.

  34. Association between serum cholesterol levels and Alzheimer's disease in China: a case-control study

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. International journal of food sciences and nutrition 2019-01-09 Risk factors

    To examine the association between blood cholesterol concentrations and Alzheimer's disease (AD) in the Chinese elderly.

  35. The Role of Nutrients in Reducing the Risk for Noncommunicable Diseases during Aging

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Nutrients 2019-01-04 Costs and economics

    An increasing aging population worldwide accounts for a growing share of noncommunicable diseases (NCDs) of the overall social and economic burden.

  36. A Systematic Review of Meta-Analyses that Evaluate Risk Factors for Dementia to Evaluate the Quantity, Quality, and Global Representativeness of Evidence

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. Journal of Alzheimer's disease : JAD 2019-01-01 Drug development

    There is a lack of midlife specific data, limited data on VaD, and a lack of geographical representation for many risk factors for dementia.

  37. Variability in metabolic parameters and risk of dementia: a nationwide population-based study

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Alzheimer's research & therapy 2018-10-27 Risk factors

    A total of 32,901 (1.12%) participants developed dementia, of which 74.4% and 11.0% were attributable to Alzheimer's disease and vascular dementia, respectively, during the median follow-up of 5.5 years.

  38. Multidomain Lifestyle Intervention Strategies for the Delay of Cognitive Impairment in Healthy Aging

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Nutrients 2018-10-21 Prevention trials

    Present demographic changes demonstrate that the number of elderly people is growing at a frenetic pace.

  39. Corroboration of a Major Role for Herpes Simplex Virus Type 1 in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Frontiers in aging neuroscience 2018-10-19 Costs and economics

    Strong evidence has emerged recently for the concept that herpes simplex virus type 1 (HSV1) is a major risk for Alzheimer's disease (AD).

  40. The Impact of Gender on Atrial Fibrillation Incidence and Progression to Dementia

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. The American journal of cardiology 2018-08-03 Risk factors

    There are a paucity of data regarding the role of gender and atrial fibrillation (AF) on cognitive decline and incidence of dementia.

  41. Association of Cardiovascular Health Level in Older Age With Cognitive Decline and Incident Dementia

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. JAMA 2018-08-01 Prevention trials

    In this cohort of older adults, increased numbers of optimal cardiovascular health metrics and a higher cardiovascular health score were associated with a lower risk of dementia and lower rates of cognitive decline.

  42. Cohort Profile Update: The Irish Longitudinal Study on Ageing (TILDA)

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. International Journal of Epidemiology 2018-07-14 End-of-life care

    As outlined in the original cohort profile,1 The Irish Longitudinal Study on Ageing (TILDA) is a prospective cohort study designed to provide an evidence base for addressing the challenges and opportunities associated with population ageing in Ireland.

  43. Comparative efficacy and acceptability of antidiabetic agents for Alzheimer's disease and mild cognitive impairment: A systematic review and network meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 76 out of 100. Diabetes, obesity & metabolism 2018-06-19 Drug development

    This study (registered with PROSPERO, CRD42018085967) compares the efficacy (i.e. pro-cognitive effects) and acceptability of antidiabetic agents for Alzheimer's disease (AD) and mild cognitive impairment (MCI).

  44. Metabolically healthy obesity and risk of leukoaraiosis; a population based cross-sectional study

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Endocrine journal 2018-04-10 Risk factors

    Metabolically healthy obese (MHO) individual is known to be defended from the metabolic complications of obesity.

  45. Mediterranean Diet in Preventing Neurodegenerative Diseases

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Current nutrition reports 2018-03 Prevention and risk

    We reviewed the most recent literature examining the associations between the Mediterranean-style diet (MD), neurodegenerative diseases, and markers and mechanisms of neurodegeneration.

  46. The role of statins in both cognitive impairment and protection against dementia: a tale of two mechanisms

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Translational neurodegeneration 2018-02-27 Drug development

    Nearly 30% of adults 40 years and older in the United States are on a statin.

  47. Metabolic Syndrome and Amyloid Accumulation in the Aging Brain

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Journal of Alzheimer's disease : JAD 2018 Risk factors

    A total of 165 cognitively normal participants of the Baltimore Longitudinal Study of Aging (BLSA) Neuroimaging substudy, aged 55-92 years (mean baseline age = 76.4 years, 85 participants were male), received an average of 2.5 PET-PiB scans over an average interval of 2.6 (3.08 SD) years between first and last visits.

  48. Metabolic Syndrome and Its Effect on the Brain: Possible Mechanism

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. CNS & neurological disorders drug targets 2018 Risk factors

    In this review, we will discuss the possible mechanisms which may relate the association between MetS and cognitive decline which include vascular damages, elevation of reactive oxygen species (ROS), insulin resistance and low-grade inflammation.

  49. Modifiable pathways in Alzheimer's disease: Mendelian randomisation analysis

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. BMJ (Clinical research ed.) 2017-12-06 Prevention and risk

    These results provide support that higher educational attainment is associated with a reduced risk of Alzheimer's disease.

  50. DHA supplementation improves cognitive function via enhancing Aβ-mediated autophagy in Chinese elderly with mild cognitive impairment: a randomised placebo-controlled trial

    ✓ Peer-reviewed alzhub usefulness score 76 out of 100. Journal of neurology, neurosurgery, and psychiatry 2017-11-15 Biomarkers

    Daily oral DHA supplementation (2 g/day) for 24 months may improve cognitive function and change blood biomarker-related Aβ-mediated autophagy in people with MCI.

From across this tag

6 of the 304 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 6. The same 6 appear here every time.

All topic tags with their study counts