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Newest in this topic

  1. Interventions for Cognitive Impairment in Type 2 Diabetes Mellitus: An Umbrella Review of Pharmacological and Lifestyle Strategies, Mechanisms, and Clinical Implications 2026-10-26
  2. Visit-to-Visit Blood Pressure Variability, Glycemic Status and the Risk of Dementia, Stroke, and All-Cause Mortality: A UK Biobank Cohort Study 2026-10-13
  3. Plasma metabolomic profiling of frailty in older adults at risk of dementia 2026-10-08

Studies

304 studies carry this tag.

Date range

1984 to 2026

Top journals

  • Journal of Alzheimer's disease : JAD 21
  • medRxiv 16
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 14
  • Neurology 10
  • Nutrients 10

164 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Supplementation with DHA and the psychological functioning of young adults

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. The British journal of nutrition 2012-04-13 Clinical trials

    The grey matter of the brain contains high levels of the essential nutrient DHA.

  2. Red blood cell ω-3 fatty acid levels and markers of accelerated brain aging

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Neurology 2012-02-01 Prevention trials

    Lower RBC DHA levels are associated with smaller brain volumes and a "vascular" pattern of cognitive impairment even in persons free of clinical dementia.

  3. Cognitive impairment and vitamin B12: a review

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. International psychogeriatrics 2012-01-06 Drug development

    Low serum vitamin B12 levels are associated with neurodegenerative disease and cognitive impairment.

  4. Cholesterol level and statin use in Alzheimer disease: I. Review of epidemiological and preclinical studies

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Archives of neurology 2011-10-01 Drug development

    During the last 2 decades, evidence has accumulated that a high cholesterol level may increase the risk of developing Alzheimer disease (AD).

  5. Risk factors and preventive interventions for Alzheimer disease: state of the science

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Archives of neurology 2011-05-09 Prevention trials

    Currently, insufficient evidence exists to draw firm conclusions on the association of any modifiable factors with risk of AD.

  6. Beneficial effects of docosahexaenoic acid on cognition in age-related cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 78 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2010-11-01 Clinical trials

    Twenty-four week supplementation with 900 mg/d DHA improved learning and memory function in ARCD and is a beneficial supplement that supports cognitive health with aging.

  7. Promoting Successful Cognitive Aging: A Comprehensive Review

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Journal of Alzheimer s Disease 2010-03-11 Drug development

    Promoting successful cognitive aging is a topic of major importance to individuals and the field of public health.

  8. Metabolic syndrome and risk of dementia in older adults

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Journal of the American Geriatrics Society 2010-03 Risk factors

    Risk of overall dementia and its subtypes was not associated with MetS or any MetS component in participants younger than 75.

  9. Cigarette Smoking is a Risk Factor for Alzheimer's Disease: An Analysis Controlling for Tobacco Industry Affiliation

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Journal of Alzheimer s Disease 2010-01-07 Prevention and risk

    To examine the relationship between smoking and Alzheimer's disease (AD) after controlling for study design, quality, secular trend, and tobacco industry affiliation of the authors, electronic databases were searched; 43 individual studies met the inclusion criteria.

  10. Risk factors for dementia

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of the Formosan Medical Association = Taiwan yi zhi 2009-10-01 Prevention trials

    Dementia is a complex human disease. The incidence of dementia among the elderly population is rising rapidly worldwide.

  11. Pravastatin and cognitive function in the elderly. Results of the PROSPER study

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Journal of neurology 2009-08-04 Drug development

    Observational studies have given conflicting results about the effect of statins in preventing dementia and cognitive decline.

  12. Change in Blood Pressure and Incident Dementia

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Hypertension 2009-06-30 Drug development

    Studies of the association of high blood pressure (BP) with dementia are not consistent.

  13. The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. International psychogeriatrics 2009-05-27 Brain scans and imaging

    The participants comprising the AIBL cohort represent a group of highly motivated and well-characterized individuals who represent a unique resource for the study of AD.

  14. Meta-analysis of Alzheimer's disease risk with obesity, diabetes, and related disorders

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Biological psychiatry 2009-04-09 Genetics

    Obesity and diabetes significantly and independently increase risk for AD.

  15. Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Journal of neurology, neurosurgery, and psychiatry 2008-10-17 Drug development

    In the general population, the use of statins, but not of non-statin cholesterol-lowering drugs, was associated with a lower risk of AD compared with never use of cholesterol-lowering drugs.

  16. Adherence to Mediterranean diet and health status: meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 83 out of 100. BMJ (Clinical research ed.) 2008-09-11 Prevention and risk

    Greater adherence to a Mediterranean diet is associated with a significant improvement in health status, as seen by a significant reduction in overall mortality (9%), mortality from cardiovascular diseases (9%), incidence of or mortality from cancer (6%), and incidence of Parkinson's disease and Alzheimer's disease (13%).

  17. Effect of fish oil on cognitive performance in older subjects

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Neurology 2008-08-04 Clinical trials

    The mean age of the participants was 70 years, and 55% were male.

  18. Alzheimer's disease, amnestic mild cognitive impairment, and age-associated memory impairment: current understanding and progress toward integrative prevention

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Alternative medicine review : a journal of clinical therapeutic 2008-06-01 End-of-life care

    Alzheimer's disease, AD, is the most common form of dementia.

  19. Diet and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Current neurology and neuroscience reports 2007-09 Prevention and risk

    Alzheimer's disease (AD) is increasing in prevalence.

  20. Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Neurology 2007-08-01 Drug development

    These findings demonstrate an association between antecedent statin use and neurofibrillary tangle burden at autopsy.

  21. Metabolic syndrome and dementia risk in a multiethnic elderly cohort

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Dementia and geriatric cognitive disorders 2007-07-18 Risk factors

    No association was found between MeSy and prevalent dementia.

  22. Inflammatory markers and the risk of Alzheimer disease: the Framingham Study

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Neurology 2007-05-01 Long-term cohort studies

    Higher spontaneous production of interleukin 1 or tumor necrosis factor alpha by peripheral blood mononuclear cells may be a marker of future risk of Alzheimer disease (AD) in older individuals.

  23. Mediterranean Diet, Alzheimer Disease, and Vascular Mediation

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Archives of Neurology 2006-10-10 Risk factors

    Higher adherence to the MeDi was associated with lower risk for AD (odds ratio, 0.76; 95% confidence interval, 0.67-0.87; P<.001).

  24. Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 1: micronutrients

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The journal of nutrition, health & aging 2006-09-01 Drug development

    More specifically, the full genetic potential of the child for physical growth ad mental development may be compromised due to deficiency (even subclinical) of micronutrients.

  25. Nutrition in brain development and aging: role of essential fatty acids

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nutrition reviews 2006-05-01 Brain scans and imaging

    The essential fatty acids (EFAs), particularly the n-3 long-chain polyunsaturated fatty acids (LCPs), are important for brain development during both the fetal and postnatal period.

  26. A life-course approach to the aetiology of late-onset dementias

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. The Lancet. Neurology 2006-01-01 Disparities

    Substantial progress has been made in the understanding of the neurobiology of dementias, but comprehensive causal models are not available.

  27. Fish consumption and cognitive decline with age in a large community study

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Archives of neurology 2005-10-10 Prevention trials

    Fish consumption may be associated with slower cognitive decline with age.

  28. Relationship between arterial stiffness and cognitive function in elderly subjects with complaints of memory loss

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Stroke 2005-09-08 Drug development

    Our results showed a relationship between arterial stiffness and cognitive impairment, suggesting that functional changes of the arterial system could be involved in the onset of dementia (VaD or AD types).

  29. Statin use and the risk of incident dementia: the Cardiovascular Health Study

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Archives of neurology 2005-07-01 Drug development

    In this cohort study, statin therapy was not associated with a decreased risk of dementia.

  30. The Relationship between Impaired Glucose Tolerance, Type 2 Diabetes, and Cognitive Function

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Clinical and Experimental Neuropsychology 2004-11-01 Risk genes beyond APOE

    The present review integrates findings of published studies that have evaluated the cognitive function of treated and untreated type 2 diabetic patients and provides a detailed overview of the neuropsychological assessments conducted.

  31. Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. BMJ 2004-08-10 Prevention and risk

    Participants who drank no alcohol at midlife and those who drank alcohol frequently were both twice as likely to have mild cognitive impairment in old age as those participants who drank alcohol infrequently.

  32. This double-blind randomized trial does not support the hypothesis that the use of soy protein supplement containing isoflavones improves cognitive function, bone mineral density, or plasma lipids in healthy postmenopausal women when started at the age of 60 years or later.

  33. Plasma homocysteine levels and risk of Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Neurology 2004-06-01 Costs and economics

    High homocysteine levels were not associated with AD and were not related to a decrease in memory scores over time.

  34. Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Archives of neurology 2004-05-01 Risk factors

    Diabetes mellitus may be associated with an increased risk of developing AD and may affect cognitive systems differentially.

  35. Relation of plasma lipids to Alzheimer disease and vascular dementia

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Archives of neurology 2004-05-01 Costs and economics

    We found a weak relation between non-HDL-C, LDL-C, and HDL-C levels and the risk of VaD.

  36. Increased risk of type 2 diabetes in Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Diabetes 2004-02-01 Risk factors

    To address this, we first examined the prevalence of type 2 diabetes in a community-based controlled study, the Mayo Clinic Alzheimer Disease Patient Registry (ADPR), which follows patients with Alzheimer disease versus control subjects without Alzheimer disease.

  37. Free testosterone and risk for Alzheimer disease in older men

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Neurology 2004-01-27 Prevention and risk

    Diagnosis of AD was associated inversely with FTI by itself and after adjustments for age, education, smoking status, body mass index, diabetes, any cancer diagnoses, and hormone supplements.

  38. Hypertension, hypertension-clustering factors and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Neurological research 2003-09 Risk factors

    Hypertension is a risk factor for stroke, ischemic white matter lesions, silent infarcts, general atherosclerosis, myocardial infarction and cardiovascular morbidity and mortality.

  39. Trace amounts of copper in water induce beta-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2003-08-14 Prevention and risk

    Despite the crucial role played by cholesterol and copper in nutrition and normal brain function, recent evidence indicates that they may both be important factors in the etiology of Alzheimer's disease (AD).

  40. Statin-associated memory loss: analysis of 60 case reports and review of the literature

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Pharmacotherapy 2003-07-01 Drug development

    Current literature is conflicting with regard to the effects of statins on memory loss.

  41. Dietary Fats and the Risk of Incident Alzheimer Disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Archives of Neurology 2003-02-01 Risk factors

    After a mean follow-up of 3.9 years, 131 persons developed Alzheimer disease.

  42. Low blood pressure and risk of dementia in the Kungsholmen project: a 6-year follow-up study

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Archives of neurology 2003-02-01 Drug development

    Both low diastolic and high systolic pressure are associated with an increased risk of Alzheimer disease and dementia in this elderly population.

  43. Vascular Factors and Risk of Dementia: Design of the Three-City Study and Baseline Characteristics of the Study Population

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Neuroepidemiology 2003-01-01 Risk factors

    After exclusion of the participants who had subsequently refused the medical interview, the 3C Study sample consisted of 3,649 men (39.3%) and 5,645 women, mean age 74.4 years, with a relatively high level of education and income.

  44. Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial

    ✓ Peer-reviewed alzhub usefulness score 76 out of 100. Annals of neurology 2002-09-01 Drug development

    In a randomized, placebo-controlled, double-blind study, we investigated whether statins alter cholesterol metabolites and reduce Abeta levels in the cerebrospinal fluid of 44 patients with Alzheimer's disease.

  45. Serum lipoprotein levels, statin use, and cognitive function in older women

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Archives of neurology 2002-03-01 Drug development

    High LDL and total cholesterol levels are associated with cognitive impairment, and lowering these lipoprotein levels may be a strategy for preventing impairment.

  46. Co-morbidity associated with dementia

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. American journal of Alzheimer's disease and other dementias 2002 Risk factors

    After adjusting for age, race, and gender, persons with Alzheimer's disease and dementia associated with medical conditions were less likely to be diagnosed with hypertension, diabetes, congestive heart failure, and atrial fibrillation than were controls.

  47. Homocysteine, vascular dementia and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Clinical chemistry and laboratory medicine 2001-08 Clinical trials

    There is some evidence from recent observational studies that hyperhomocysteinemia is a risk factor for cognitive dysfunction, including Alzheimer's disease and vascular dementia.

  48. The nature of the effect of female gonadal hormone replacement therapy on cognitive function in post-menopausal women: a meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Neuroscience 2000-01-01 Prevention and risk

    We reviewed epidemiological and experimental studies of female gonadal hormone replacement therapy (HRT) on cognitive function in post-menopausal women and carried out meta-analyses.

  49. 46 (4.7%) subjects were classified as having probable or possible Alzheimer's disease.

  50. A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: the Baltimore Longitudinal Study of Aging

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Neurology 1997-06-01 Risk factors

    Previous reports have suggested that estrogen replacement therapy (ERT) in women may exert a protective effect on their risk of developing Alzheimer's disease (AD).

From across this tag

10 of the 304 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

All topic tags with their study counts