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metabolic-syndrome
304 studies tagged metabolic-syndrome, dated 1984-04-01 to 2026-10-26. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Interventions for Cognitive Impairment in Type 2 Diabetes Mellitus: An Umbrella Review of Pharmacological and Lifestyle Strategies, Mechanisms, and Clinical Implications 2026-10-26
- Visit-to-Visit Blood Pressure Variability, Glycemic Status and the Risk of Dementia, Stroke, and All-Cause Mortality: A UK Biobank Cohort Study 2026-10-13
- Plasma metabolomic profiling of frailty in older adults at risk of dementia 2026-10-08
Studies
304 studies carry this tag.
Date range
1984 to 2026
Top journals
- Journal of Alzheimer's disease : JAD 21
- medRxiv 16
- Alzheimer's & dementia : the journal of the Alzheimer's Association 14
- Neurology 10
- Nutrients 10
164 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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The intervention was feasible and acceptable with the intended number of participants completing the study.
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Six prospective cohort studies with seven datasets, including 484,994 participants and a follow-up of 3.5 to 13.0 years, were included.
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Higher concentrations of pTau181 and GFAP were associated with slower responses on working memory tasks (pTau181: β = 0.261; p = 0.007; GFAP: β = 0.175, p = 0.036), and higher β-amyloid 42/40 ratio was associated with better vocabulary (β = 0.260, p = 0.009).
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Due to the continuous aging of the population and consequent increase in dementia, focus on its prevention is of growing importance for public health.
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Recent studies have explored the impact of lifestyle, particularly diet, on cognitive decline and Alzheimer's disease (AD) risk.
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Due to increasing lifespan and aging populations globally there has been a steep rise in late-life dementia, which is now the second most common cause of death in high-income countries.
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57/100
There is substantial evidence supporting the neuroprotective effects of the MIND diet in neurodegenerative diseases like Parkinson's and Alzheimer's. Our aim was to evaluate the impact of a nutritional intervention (NI) with this diet on multiple sclerosis (MS) patients.
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Alzheimer's disease (AD) remains a widespread cause of dementia globally, and its prevalence is increasing due to the aging population.
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Increased absolute sugar intake (g/day) was significantly associated with a higher risk of all-cause dementia (HR = 1.003, [95%CI: 1.002-1.004], p < 0.001) and Alzheimer's disease (1.002, [1.001-1.004], 0.005).
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We searched 122 studies, of which 90 were included in our analysis.
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A total of 717 articles were identified, showing an upward trend in annual publications.
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Hippocampal neurogenesis (HN) occurs throughout the life course and is important for memory and mood.
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This mini-narrative review explores the relationship between diabetes and dementia, focusing on the potential mitigating role of metformin in reducing cognitive decline among individuals with type 2 diabetes.
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The MR analysis conducted in this study found no statistically significant causal association between 20 dietary habits and the risk of AD (All p > 0.05).
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Numerous longitudinal studies suggest a strong association between cardiovascular risk factors and cognitive impairment.
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This study aimed to investigate the controversial association between metformin use and diabetes-associated dementia in elderly patients with type 2 diabetes mellitus (T2DM) and evaluate the potential protective effects of metformin, as well as its intensity of use and dose-dependency, against dementia in this population.
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Levels of 24(S)-hydroxycholesterol (24-OHC), 27-hydroxycholesterol (27-OHC), and 24-OHC/27-OHC ratio did not differ by APOE status (p's > 0.05).
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A total of 45 reviews with 212 meta-analyses were synthesized.
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Dementia is one of the most significant global challenges in medical and social care in the 21st century.
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The results showed that log-transformed serum Aβ42 level was positively correlated with BMI (R = 0.29; p < 0.001), log-transformed triglyceride (R = 0.14; p < 0.001), and diastolic blood pressure (DBP) (R = 0.12; p < 0.001) and negatively correlated with high-density lipoprotein (HDL-c) (R = -0.18; p < 0.001).
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Screening commenced in July 2022. Currently, 1,965 participants have been randomized into lifestyle intervention (n = 772) and control groups (n = 1,193).
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Amyloid-β (Aβ)42 and arterial calcification were associated with cognitive performance.
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Dementia is a growing concern and underscores the urgent need for effective preventive measures targeting modifiable risk factors.
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Nicotinamide riboside (NR) increases blood levels of NAD+, a cofactor central to energy metabolism, and improves brain function in some rodent models of neurodegeneration.
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several dietary components have been positively associated with AD prevention, including intake of complex carbohydrates, fiber, omega-3, plant-based proteins, vitamins (folates, choline, vitamin D, C, B6 and B9), zinc, some bioactive compounds such as flavonols and probiotics.
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Metformin, thiazolidinediones, pioglitazone, GLP1RAs and SGLT2is were associated with reduced risk of dementia.
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The objective of this study was to evaluate the relation of metformin with change in cognition and brain pathology.
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Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterized by memory loss and multiple cognitive impairments.
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Studies have shown that multimorbidity may be associated with the Alzheimer's disease (AD) stages, but it has not been fully characterized in patients without dementia.
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After ≤15 years, 5,491 all-cause dementia cases were diagnosed.
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Mediterranean diet (MD) accurately lowers AD (Alzheimer's Disease) risk to 53% and 35% for people who follow it moderately.
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41/100
Stroke has three main subtypes - ischemic stroke, intracerebral hemorrhage, and subarachnoid hemorrhage.
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Dementia is a growing public health concern, with an estimated prevalence of 57 million adults worldwide.
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Currently, 1549 participants have been screened, and 815 randomized.
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Multivariable linear regressions showed an association of metabolic syndrome with lower performance in attention (β=1.62 seconds, 95% CI=0.20, 3.04) and memory (β=-0.62 words, 95% CI=-1.19, -0.05) that could be driven by associations with elevated fasting glucose and abdominal obesity.
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The results show that the western diet pattern is a risk factor for developing AD.
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Alzheimer's disease (AD) is a common neurodegenerative disease characterized by amyloid plaques and impaired brain metabolism.
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Whether initiation of statins could increase survival free of dementia and disability in adults aged ≥75 years is unknown.
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One of the most common medical diseases is metabolic syndrome (MetS), which encompasses diabetes and obesity.
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With rapid aging of the population worldwide, the number of people with dementia is dramatically increasing.
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A high-protein and alcohol dietary pattern was negatively associated with cortical thickness in the whole brain (Beta: -0.011; 95% confidence interval [CI]: -0.018 to -0.003), and with an Alzheimer's disease cortical thickness signature score (Beta: -0.013; 95% CI: -0.024 to -0.001).
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No significant disparities in plasma ubiquitin levels for various levels of cognitive functioning were identified.
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In univariate analysis, all 29 adiposity and metabolic measures assessed were associated with ' g ' at P < 0.05.
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Twenty-five meta-analyses published between 2007 and 2021 were included.
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The number of people living with dementia, such as Alzheimer's disease, is increasing worldwide.
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Diet is an important nonpharmacological risk-modifying factor for Alzheimer's disease (AD).
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Polyphenols, folate, vitamin D, omega-3 fatty acids, and β-carotene might decrease the risk of dementia.
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The search generated 33 papers, which yielded 11 articles after screening.
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Cognitive impairment has become an important aspect affecting the health and quality of life of middle-aged and elderly people, which is defined as the difficulty of thought processing and leads to memory loss, difficulties making decisions, the inability to concentrate, and difficulties learning.
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Alzheimer's disease (AD) is a neurodegenerative disease with significant socioeconomic burden worldwide.
From across this tag
9 of the 304 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.
- Statin therapy and risk of Alzheimer's and age-related neurodegenerative diseases
- Metabolic Syndrome: Is It Time to Add the Central Nervous System?
- Exploration of the molecular origins of sex-specific and temporal comorbidity patterns in dementia: insights from the Austrian claims data
- Cardiovascular risk and midlife cognitive decline in the Study of Women's Health Across the Nation
- Effects of Regular and Long-Acting Insulin on Cognition and Alzheimer's Disease Biomarkers: A Pilot Clinical Trial
- Metabolic Syndrome, Cognitive Impairment and the Role of Diet: A Narrative Review
- Causal inference in medical records and complementary systems pharmacology for metformin drug repurposing towards dementia
- Fish consumption and cognitive decline with age in a large community study
- Towards a Consensus on Alzheimer's Disease Comorbidity?