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Home › Research › Topic

Gut, metabolism and diet

1,048 studies in this group. A computer grouped them by what their titles and summaries are about, not by a hand-made list. The name describes most of the group, not every study in it.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Download bibliography of all 1,048 studies, highest score first: BibTeX (.bib) · RIS (.ris)

Highest usefulness score first. Studies without a score come last.

  1. Melatonin and climactery

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Medical science monitor : international medical journal of experimental and clinical research 2000 Risk factors

    Melatonin is a hormone synthesized in the pineal gland from tryptophan.

  2. Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nutrition reviews 2016-10-01 Prevention and risk

    It has been hypothesized that alterations in the composition of the gut microbiota might be associated with the onset of certain human pathologies, such as Alzheimer disease, a neurodegenerative syndrome associated with cerebral accumulation of amyloid-β fibrils.

  3. Interactions between inflammation, sex steroids, and Alzheimer's disease risk factors

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Frontiers in neuroendocrinology 2016-09-17 Risk factors

    Alzheimer's disease (AD) is an age-related neurodegenerative disorder for which there are no effective strategies to prevent or slow its progression.

  4. Alzheimer's disease and gut microbiota

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Science China. Life sciences 2016-08-26 Disease mechanisms

    Alzheimer's disease (AD) is a most common neurodegenerative disorder, which associates with impaired cognition.

  5. The Gut-Brain Axis, BDNF, NMDA and CNS Disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurochemical research 2016-08-23 Disease mechanisms

    Gastro-intestinal (GI) microbiota and the 'gut-brain axis' are proving to be increasingly relevant to early brain development and the emergence of psychiatric disorders.

  6. The bowel and beyond: the enteric nervous system in neurological disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nature reviews. Gastroenterology & hepatology 2016-07-20 Disease mechanisms

    The enteric nervous system (ENS) is large, complex and uniquely able to orchestrate gastrointestinal behaviour independently of the central nervous system (CNS).

  7. Subcutaneous administration of liraglutide ameliorates learning and memory impairment by modulating tau hyperphosphorylation via the glycogen synthase kinase-3β pathway in an amyloid β protein induced alzheimer disease mouse model

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. European journal of pharmacology 2016-04-27 Drug development

    Type 2 diabetes mellitus is a risk factor for Alzheimer's disease (AD).

  8. Diabetes and Alzheimer's disease crosstalk

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuroscience and biobehavioral reviews 2016-03-09 End-of-life care

    Despite intensive research efforts over the past few decades, the mechanisms underlying the etiology of sporadic Alzheimer's disease (AD) remain unknown.

  9. The glucagon-like peptide 1 (GLP) receptor as a therapeutic target in Parkinson's disease: mechanisms of action

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Drug discovery today 2016-02-03 Drug development

    Growing evidence suggests that agonists of the glucagon-like peptide 1 (GLP-1) receptor provide neuroprotection across a range of experimental models of Parkinson's disease (PD) and, recently, a small proof-of-concept, open-label human trial of exenatide in the treatment moderate severity PD appeared to show persistent improvements in motor and cognitive function.

  10. Neuroprotective effects of glucose-dependent insulinotropic polypeptide in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Reviews in the neurosciences 2016-01-01 Drug development

    Glucose-dependent insulinotropic polypeptide (GIP) is a member of the incretin hormones and growth factors.

  11. Gut microbiota in autism and mood disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. World journal of gastroenterology 2016-01-01 Disease mechanisms

    The hypothesis of an important role of gut microbiota in the maintenance of physiological state into the gastrointestinal (GI) system is supported by several studies that have shown a qualitative and quantitative alteration of the intestinal flora in a number of gastrointestinal and extra-gastrointestinal diseases.

  12. Novel GLP-1 (Glucagon-Like Peptide-1) Analogues and Insulin in the Treatment for Alzheimer's Disease and Other Neurodegenerative Diseases

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. CNS drugs 2015-12-01 Drug development

    The link between diabetes mellitus and Alzheimer's disease (AD) has been known for the last few decades.

  13. Gut microbiome in health and disease: Linking the microbiome-gut-brain axis and environmental factors in the pathogenesis of systemic and neurodegenerative diseases

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Pharmacology & therapeutics 2015-11-26 Disease mechanisms

    The gut microbiome comprises the collective genome of the trillions of microorganisms residing in our gastrointestinal ecosystem.

  14. Pomegranate's Neuroprotective Effects against Alzheimer's Disease Are Mediated by Urolithins, Its Ellagitannin-Gut Microbial Derived Metabolites

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. ACS chemical neuroscience 2015-11-17 Disease mechanisms

    Pomegranate shows neuroprotective effects against Alzheimer's disease (AD) in several reported animal studies.

  15. Neurodegenerative diseases: From available treatments to prospective herbal therapy

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurochemistry international 2015-11-10 End-of-life care

    Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and many others represent a relevant health problem with age worldwide.

  16. A novel dual GLP-1 and GIP receptor agonist is neuroprotective in the MPTP mouse model of Parkinson's disease by increasing expression of BNDF

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Brain research 2015-10-11 Drug development

    The incretins glucagon-like peptide 1 (GLP-1) and glucose dependent insulinotropic polypeptide (GIP) are growth factors with neuroprotective properties.

  17. Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015-08-07 Disease mechanisms

    Mitochondria is one of the main source of oxidative stress (ROS), as it utilizes the oxygen for the energy production.

  18. Prophylactic liraglutide treatment prevents amyloid plaque deposition, chronic inflammation and memory impairment in APP/PS1 mice

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Behavioural brain research 2015-07-20 Drug development

    Type 2 diabetes is a risk factor for Alzheimer's disease (AD).

  19. Neuroprotective effects of lixisenatide and liraglutide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuroscience 2015-07-02 Drug development

    Glucagon-like peptide 1 (GLP-1) is a growth factor.

  20. HMG-CoA Reductase Inhibitors Bind to PPARα to Upregulate Neurotrophin Expression in the Brain and Improve Memory in Mice

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Cell metabolism 2015-06-25 Drug development

    Neurotrophins are important for neuronal health and function.

  21. Checks and balances on cholinergic signaling in brain and body function

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Trends in neurosciences 2015-06-20 Risk factors

    A century after the discovery of acetylcholine (ACh), we recognize both ACh receptors, transporters, and synthesizing and degrading enzymes and regulators of their expression as contributors to cognition, metabolism, and immunity.

  22. Gut-brain connection: The neuroprotective effects of the anti-diabetic drug liraglutide

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. World journal of diabetes 2015-06-01 Drug development

    Long-acting glucagon-like peptide-1 (GLP-1) analogues marketed for type 2 diabetes (T2D) treatment have been showing positive and protective effects in several different tissues, including pancreas, heart or even brain.

  23. Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Molecular nutrition & food research 2015-04-27 Disease mechanisms

    Scope Grape seed polyphenol extract (GSPE) is receiving increasing attention for its potential preventative and therapeutic roles in Alzheimer's disease (AD) and other age-related neurodegenerative disorders.

  24. Anti-Inflammatory and Antiatherogenic Effects of the NLRP3 Inflammasome Inhibitor Arglabin in ApoE 2 .Ki Mice Fed a High-Fat Diet

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Circulation 2015-03-24 Genetics

    A marked reduction in atherosclerotic lesions was observed.

  25. Regulatory Effects of Caffeic Acid Phenethyl Ester on Neuroinflammation in Microglial Cells

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. International Journal of Molecular Sciences 2015-03-11 Inflammation and the immune system

    Microglial activation has been widely demonstrated to mediate inflammatory processes that are crucial in several neurodegenerative disorders.

From across this topic

10 of the 1,048 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

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