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Home › Research › Topic

Gut, metabolism and diet

1,048 studies in this group. A computer grouped them by what their titles and summaries are about, not by a hand-made list. The name describes most of the group, not every study in it.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. Metabolic, inflammatory, and microvascular determinants of white matter disease and cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. American journal of neurodegenerative disease 2016-11-30 Risk factors

    White Matter Disease is increasingly being recognized as an important cause of cognitive decline and dementia.

  2. Adaptive responses of neuronal mitochondria to bioenergetic challenges: Roles in neuroplasticity and disease resistance

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Free radical biology & medicine 2016-11-29 Prevention trials

    An important concept in neurobiology is "neurons that fire together, wire together" which means that the formation and maintenance of synapses is promoted by activation of those synapses.

  3. Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Neurological research 2016-11-03 Risk factors

    Reactive species play an important role in physiological functions.

  4. Glucagon-like Peptide-1 and the Central/Peripheral Nervous System: Crosstalk in Diabetes

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Trends in endocrinology and metabolism: TEM 2016-10-27 Drug development

    Glucagon-like peptide-1 (GLP-1) is released in response to meals and exerts important roles in the maintenance of normal glucose homeostasis.

  5. Ginkgolic Acid Protects against Aβ-Induced Synaptic Dysfunction in the Hippocampus

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Frontiers in pharmacology 2016-10-26 Disease mechanisms

    Ginkgo leaf is the most used form of supplement for cognitive ailments.

  6. Oxidative Stress and the Central Nervous System

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. The Journal of pharmacology and experimental therapeutics 2016-10-17 Risk factors

    Biochemical integrity of the brain is vital for normal functioning of the central nervous system (CNS).

  7. Linagliptin, a Dipeptidyl Peptidase-4 Inhibitor, Mitigates Cognitive Deficits and Pathology in the 3xTg-AD Mouse Model of Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Molecular neurobiology 2016-10-03 Drug development

    Glucagon-like peptide-1 (GLP-1) is an incretin hormone shown to be active in the treatment of type-2 diabetes (T2D) and has also been shown as efficacious in Alzheimer's disease (AD).

  8. From focal sepsis to periodontal medicine: a century of exploring the role of the oral microbiome in systemic disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. The Journal of physiology 2016-08-28 Disease mechanisms

    The oral microbiome is established within a few minutes after birth and consists of stable multi-species communities that engage in a dynamic equilibrium with the host immune system.

  9. [Nutrition and cognitive impairment]

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Nutricion hospitalaria 2016-07-12 Prevention and risk

    Dementia, closely linked to environmental predisposing factors such as diet, is a public health problem of increasing magnitude: currently there are more than 35 million patients with Alzheimer´s disease, and is expected to exceed 135 million by 2050.

  10. Oxidative stress, protein modification and Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Brain research bulletin 2016-06-15 Genetics

    Alzheimer disease (AD) is a progressive neurodegenerative disease that affects the elderly population with complex etiology.

  11. Aging and Neurodegeneration: A Tangle of Models and Mechanisms

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Aging and disease 2016-03-15 Disease mechanisms

    The research on aging and age-related diseases, especially the neurodegenerative diseases, is on the fast track.

  12. Metformin Facilitates Amyloid-β Generation by β- and γ-Secretases via Autophagy Activation

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of Alzheimer's disease : JAD 2016 Drug development

    The evidence of strong pathological associations between type 2 diabetes and Alzheimer's disease (AD) has increased in recent years.

  13. Multi-Nutrient Dietary Intervention Approach to the Management of Alzheimer's Disease - A Mini-Review

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Current Alzheimer research 2016 Prevention and risk

    Alzheimer's disease (AD) is currently the most common incurable forms of dementia.

  14. Exendin-4 reduces tau hyperphosphorylation in type 2 diabetic rats via increasing brain insulin level

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Molecular and cellular neurosciences 2015-11-27 Drug development

    Type 2 diabetes (T2D) is a high risk factor for Alzheimer's disease (AD).

  15. Early intervention with glucagon-like peptide 1 analog liraglutide prevents tau hyperphosphorylation in diabetic db/db mice

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of neurochemistry 2015-08-11 Drug development

    Increasing evidence has shown that type 2 diabetes (T2D) is a risk factor for Alzheimer's disease.

  16. Recent data on Mediterranean diet, cardiovascular disease, cancer, diabetes and life expectancy

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Bratislavske lekarske listy 2015 Prevention and risk

    Benefits of dietary moderation when on a Mediterranean diet type (MD) have been known for well over half a century.

  17. Peptide Vaccines for Hypertension and Diabetes Mellitus

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Vaccines 2014-11-26 Risk factors

    Vaccines are commonly used as a preventive medicine for infectious diseases worldwide; however, the trial for an amyloid beta vaccine against Alzheimer's disease will open a new concept in vaccination.

  18. [Metabolic syndrome]

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Nihon rinsho. Japanese journal of clinical medicine 2014-04 Risk factors

    Considerable attention has focused on the prevention of dementia in terms of non-genetic risk factors, including midlife obesity, especially visceral obesity associated with hyperglycemia, hypertension, and hypercholesterolemia.

  19. Glucagon-like peptide-1 protects synaptic and learning functions from neuroinflammation in rodents

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of neuroscience research 2014-01-27 Drug development

    Glucagon-like peptide-1 (GLP-1) is derived from the processing of proglucagon in intestinal L-cells and releases insulin from pancreatic β-cells as an incretin.

  20. Targeting synaptic dysfunction in Alzheimer's disease by administering a specific nutrient combination

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of Alzheimer's disease : JAD 2014 Disease mechanisms

    Synapse loss and synaptic dysfunction are pathological processes already involved in the early stages of Alzheimer's disease (AD).

  21. Cardiorenal metabolic syndrome and diabetic cognopathy

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Cardiorenal medicine 2013-11-29 Risk factors

    The prevalence of the cardiorenal metabolic syndrome (CRS) is increasing in parallel with obesity, type 2 diabetes mellitus, Alzheimer's disease, and other forms of dementia.

  22. Galantamine potentiates the neuroprotective effect of memantine against NMDA-induced excitotoxicity

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Brain and behavior 2013-01-11 Treatments

    The combination of memantine, an N-methyl-d-aspartate (NMDA) receptor antagonist, with an acetylcholinesterase inhibitor (AChEI) is the current standard of care in Alzheimer's disease (AD).

  23. Oxidative stress and human health

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Advances in Bioscience and Biotechnology 2012-01-01 Brain scans and imaging

    Redox degenerative reactions of the biological system inevitably produce reactive oxygen species (ROS) and their derivatives.

  24. Metabolic links between diabetes and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Expert review of neurotherapeutics 2009-05 Risk factors

    There is a cluster of risk factors for Type 2 diabetes and vascular disease that include high blood glucose, obesity, high blood pressure, increased blood triacylglycerols and insulin resistance.

  25. Homocysteine, vascular dementia and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Clinical chemistry and laboratory medicine 2001-08 Clinical trials

    There is some evidence from recent observational studies that hyperhomocysteinemia is a risk factor for cognitive dysfunction, including Alzheimer's disease and vascular dementia.

From across this topic

10 of the 1,048 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

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