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cohort
1,143 studies tagged cohort, dated 1978-04-01 to 2026-09-26. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Public awareness of the hearing loss-dementia link and self-reported behavioral changes in middle- to older-aged Canadians 2026-09-26
- Patterns of modifiable lifestyle, behavioural and health-related risk factors and their associations with incident dementia in UK Biobank 2026-09-25
- Excess hypoglycaemia-related hospitalisation in older adults with comorbid type 2 diabetes and dementia: a UK Biobank cohort study 2026-09-16
Studies
1,143 studies carry this tag.
Date range
1978 to 2026
Top journals
- Neurology 134
- Alzheimer s & Dementia 52
- Alzheimer's & dementia : the journal of the Alzheimer's Association 33
- Journal of the American Geriatrics Society 32
- JAMA neurology 28
362 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Exposure to several types of strong anticholinergic drugs is associated with an increased risk of dementia.
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Among older adults without cognitive impairment or dementia, both an unfavorable lifestyle and high genetic risk were significantly associated with higher dementia risk.
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Late-life declines in blood pressure following prolonged hypertension may be associated with poor cognitive outcomes.
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During a mean follow-up of 12.1 years, 1,520 individuals developed dementia, 1,194 of whom had AD.
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Incident AF was associated with an increased risk of dementia, independent of clinical stroke in an elderly population.
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59/100
Linear MR suggested that each additional hour/day of sleep was associated with 1% [95% confidence interval (CI) = 0-2%; P = 0.008] slower reaction time and 3% more errors in visual-memory test (95% CI = 0-6%; P = 0.05).
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Diabetes status, poor glycemic control, and longer diabetes duration were associated with worse cognitive outcomes over a median follow-up of 5 years.
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Sensory impairments were common: 28% had visual impairment, 35% had hearing loss, 22% had poor smell, 12% had touch insensitivity; 26% had more than two impairments, and 5.6% had more than three sensory impairments.
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The overall weighted PAF for potentially modifiable risk factors for dementia was 39·5% (95% CI 37·5-41·6) in China (n=2162 participants), 41·2% (39·1-43·4) in India (n=2004), and 55·8% (54·9-56·7) in our Latin American sample (n=12 865).
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In analyses that addressed bias due to reverse causation, physical inactivity was not associated with all-cause dementia or Alzheimer's disease, although an indication of excess dementia risk was observed in a subgroup of physically inactive individuals who developed cardiometabolic disease.
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Immunity has been suggested to be important in the pathogenesis of dementia.
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53/100
Fibroblast growth factor 23 is an emerging vascular biomarker, recently associated with cerebral small vessel disease and poor cognition in patients on dialysis.
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Clinical studies found that elevated cortisol was associated with poorer overall cognitive functioning, as well as with poorer episodic memory, executive functioning, language, spatial memory, processing speed, and social cognition; while in animals, glucocorticoid administration resulted in cognitive impairment and abnormal behavior.
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The overall conversion rate from iRBD to an overt neurodegenerative syndrome was 6.3% per year, with 73.5% converting after 12-year follow-up.
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Differences between users and non-users of insulin, metformin and sulfonylurea were assessed in each cohort for cognitive and brain MRI measures using linear regression models, and cognitive decline and dementia/AD risk using mixed effect models and Cox regression analyses, respectively.
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A total of 3,162 cases of dementia occurred during the follow-up.
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Incidence of dementia is nearly 50 times higher in the year after a major stroke compared with that in the general population, but excess risk is substantially lower after transient ischaemic attack and minor stroke.
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When compared with the Low MedDiet group, the High MedDiet group was associated with better L&M performance and larger dentate gyri.
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Among ambulatory adults with hypertension, treating to a systolic blood pressure goal of less than 120 mm Hg compared with a goal of less than 140 mm Hg did not result in a significant reduction in the risk of probable dementia.
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In China, the crude mortality from AD and other forms of dementia increased from 2009 to 2015, but the age-standardized mortality decreased.
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Dysregulation of the gut microbiome is associated with several life-threatening conditions and thus might represent a useful target for the prevention of dementia.
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Over the 3-year follow-up, almost 10% of participants developed dementia and 14% were deceased.
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Nearly half of all adults older than 60 years of age report sleep disturbance, as characterised either by reports of insomnia complaints with daytime consequences, dissatisfaction with sleep quality or quantity, or the diagnosis of insomnia disorder.
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Early-life factors, including education level, leg length, history of childhood head trauma, family-related factors and learning ability, were associated with the risk of dementia and cognitive impairment in later life.
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Socioeconomic differences in dementia risk can be partly explained by differences in modifiable health conditions and lifestyle factors.
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Several studies report an association between REM Sleep Behavior Disorder (RBD) and neurodegenerative diseases, in particular synucleinopathies.
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Stroke, dementia, and hypertension are associated with late-onset epilepsy; however, the role of other vascular and lifestyle factors remains unclear.
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Future well-designed longitudinal researches examining the direct and indirect relationship between tooth loss and dementia risk are encouraged.
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Within the prospective population-based Rotterdam Study, we studied lifetime risk of dementia, stroke and parkinsonism between 1990 and 2016.
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Retinal structures may serve as a biomarker for dementia, but longitudinal studies examining this link are lacking.
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One hundred two (37.9%) participants were amyloid positive.
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49/100
Among 104 537 individuals, the absolute 10-year risk of Alzheimer disease in 3017 women and men who were carriers of the APOE ɛ44 genotype was, respectively, 7% and 6% at age 60-69 years, 16% and 12% at age 70-79 years, and 24% and 19% at age 80 years and older.
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The mean (SD) age was 73.7 (6.0) years, and the mean (SD) follow-up time was 3.7 (1.2) years.
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Stroke is a strong, independent, and potentially modifiable risk factor for all-cause dementia.
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This 23-year study found a U-shaped relationship between alcohol and dementia risk: people who abstained from alcohol in midlife, as well as those who drank heavily (more than 14 units, about 14 standard drinks, per week), both had a higher risk of developing dementia than people who drank moderately.
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We analyzed data from 11,709 participants without a history of coronary heart disease or stroke who attended the baseline examination (1987-1989) of the prospective Atherosclerosis Risk in Communities (ARIC) study.
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We aimed to evaluate the link between severe hypoglycaemia and domain-specific cognitive decline, smaller brain volumes and dementia in adults with type 2 diabetes, which so far has been relatively poorly characterised.
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Age-related increases in dementia risk can be attributed to accumulation of multiple pathologies, each of which contributes to dementia risk.
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The interplay between midlife vascular risk factors and midlife cognitive function with later life mild cognitive impairment (MCI) and dementia (DEM) is not well understood.
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A robust association between some classes of anticholinergic drugs and future dementia incidence was observed.
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Ample epidemiological evidence suggests a strong correlation among diet, lifestyle factors and the onset and consolidation of dementia and Alzheimer's disease (AD).
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52/100
Among Swedish women, a high cardiovascular fitness in midlife was associated with a decreased risk of subsequent dementia.
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Dementia is a major source of disability worldwide and there are currently no available disease-modifying treatments.
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AF is associated with greater cognitive decline and increased risk of dementia, independent of ischemic stroke.
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We found no evidence to support the theory that natural variation in cumulative exposure to endogenous oestrogens across the reproductive period influences dementia incidence in late life.
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Of 31 624 156 adults discharged from French hospitals between 2008 and 2013, 1 109 343 were diagnosed with dementia and were included in the analyses.
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Data from 2,133 participants with autopsy-confirmed AD (i.e., at least Braak neurofibrillary tangle stages III to VI and CERAD neuritic plaque score moderate to frequent) were obtained from the National Alzheimer's Coordinating Center (NACC).
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Among women, foreign-born Hispanics have higher odds of CIND and dementia than Whites.
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60/100
Circulating metabolites were consistently associated with cognition, dementia, and lifestyle factors, opening new avenues for prevention of cognitive decline and dementia.
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62/100
Cerebral amyloid-β aggregation is an early event in Alzheimer disease (AD).
From across this tag
9 of the 1,134 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.
- Obesity, diabetes and cognitive deficit: The Framingham Heart Study
- Shingles, Zostavax vaccination and risk of developing dementia: a nested case-control study-results from the UK Biobank cohort
- Diet‐Driven Metabolite Patterns Link the MIND Diet to Dementia Biomarkers
- Increased risk of dementia in patients with mild traumatic brain injury: a nationwide cohort study
- Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition
- Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research
- BMI and risk of dementia in two million people over two decades: a retrospective cohort study
- Statin Initiation and Risk of Incident Alzheimer Disease and Cognitive Decline in Genetically Susceptible Older Adults
- Alzheimer's and dementia: Diagnosis, assessment, and disease monitoring global, regional, and national burden of Alzheimer's disease and other dementias (ADODs) and their risk factors, 1990–2021: A systematic analysis for the Global Burden of Disease study 2021