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The predictive validity of a Brain Care Score for dementia and stroke: data from the UK Biobank cohort
Singh SD, Oreskovic T, Carr S, Papier K, Conroy M, Senff JR, Chemali Z, Gutierrez-Martinez L et al.. Frontiers in neurology, 2023-12-01
Topic: Risk, prevention and care in population studies
Introduction The 21-point Brain Care Score (BCS) was developed through a modified Delphi process in partnership with practitioners and patients to promote behavior changes and lifestyle choices in order to sustainably reduce the risk of dementia and stroke. We aimed to assess the associations of the BCS with risk of incident dementia and stroke. Methods The BCS was derived from the United Kingdom Biobank (UKB) baseline evaluation for participants aged 40-69 years, recruited between 2006-2010.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Singh, S. D., Oreskovic, T., Carr, S., Papier, K., Conroy, M., Senff, JR., et al. (2023). The predictive validity of a Brain Care Score for dementia and stroke: data from the UK Biobank cohort. Frontiers in neurology. https://doi.org/10.3389/fneur.2023.1291020
Vancouver
Singh SD, Oreskovic T, Carr S, Papier K, Conroy M, Senff JR, et al. The predictive validity of a Brain Care Score for dementia and stroke: data from the UK Biobank cohort. Frontiers in neurology. 2023. doi:10.3389/fneur.2023.1291020. PMID: 38107629.
BibTeX
@article{singh2023-38107629,
author = {Singh, S. D. and Oreskovic, T. and Carr, S. and Papier, K. and Conroy, M. and Senff, JR. and Chemali, Z. and Gutierrez-Martinez, L. and others},
title = {{The predictive validity of a Brain Care Score for dementia and stroke: data from the UK Biobank cohort}},
journal = {Frontiers in neurology},
year = {2023},
doi = {10.3389/fneur.2023.1291020},
pmid = {38107629},
url = {https://doi.org/10.3389/fneur.2023.1291020}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
Key findings
- We aimed to assess the associations of the BCS with risk of incident dementia and stroke.
- Methods The BCS was derived from the United Kingdom Biobank (UKB) baseline evaluation for participants aged 40-69 years, recruited between 2006-2010.
- Associations of BCS and risk of subsequent incident dementia and stroke were estimated using Cox proportional hazard regressions, adjusted for sex assigned at birth and stratified by age groups at baseline.
- Results The BCS (median: 12; IQR:11-14) was derived for 398,990 UKB participants (mean age: 57; females: 54%).
Why it matters
This study tested whether a 21-point Brain Care Score, based on lifestyle and behavior factors, is linked to the risk of developing dementia and stroke. A higher score was associated with lower risk, suggesting that lifestyle choices may help reduce risk, though this does not prove cause and effect.
Study details
- Evidence strengthLow
How this study scored 53/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomized / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Frontiers in neurology) |
| Journal's citation record | 2 / 4 | Frontiers in Neurology: journal h-index 162 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 3 / 5 | 2023 — within 6 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomized / blinded | 0 / 2 | No randomization or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 4 / 7 | Cited 52 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 10.4 citations a year over 5 year(s) since 2023 |
| Impact for its field and year | 4 / 6 | Cited 9.4× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 3 other studies in this library |
| Still being cited | 3 / 4 | Cited 51 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author Jonathan M. Rosand: h-index 121 (OpenAlex, whole career) |
| Institution's track record | 3 / 3 | Institute for Health Metrics and Evaluation: institution h-index 3,605 (OpenAlex) |
| Multicenter collaboration | 3 / 3 | OpenAlex lists 13 institution(s) in 4 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 38107629) |
| Free to read | 2 / 2 | Free to read |
| Total | 53 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.3389/fneur.2023.1291020
- PubMed: 38107629
- Original source →
- Free full text: Frontiers in Neurology →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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