Home › Research › Digital health tools
Economic evaluation of a digital health intervention for preventing dementia in Canadians with mild cognitive impairment
Seyed‐Mohammad Fereshtehnejad, Karim Keshavjee, Peter Christopher Coyte. Frontiers in Public Health, 2025-09-19
Topic: Risk, prevention and care in population studies
Dementia poses an on-going Canadian challenge due to an aging population, with cases projected to rise significantly by 2050. This study evaluates the cost-effectiveness of a conceptual digital health intervention designed to prevent dementia in Canadians with mild cognitive impairment (MCI). The analysis is exploratory and conceptual, comparing different scenarios for the possible effectiveness of the digital intervention for dementia prevention. Using data from the Global Burden of Disease (GBD) 2021 study, a long-term economic evaluation was conducted from a healthcare payer perspective, comparing intervention costs to usual care between 2030 and 2050. Health outcome was assessed using disability-adjusted life years (DALYs) averted. The analysis revealed favorable incremental cost-effectiveness ratios (ICERs) well below conventional willingness-to-pay thresholds across all scenarios. Sensitivity analyses confirmed the robustness of these findings, underscoring the intervention's potential to cost-effectively reduce dementia burden. The findings are based on modeled assumptions in the absence of empirical efficacy data and should therefore be interpreted with caution until validated in real-world settings. Yet, these results provide valuable insights for Canadian policymakers on scalable, proactive dementia prevention strategies.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Fereshtehnejad, S., Keshavjee, K., & Coyte, P. C. (2025). Economic evaluation of a digital health intervention for preventing dementia in Canadians with mild cognitive impairment. Frontiers in Public Health. https://doi.org/10.3389/fpubh.2025.1631676
Vancouver
Fereshtehnejad S, Keshavjee K, Coyte PC. Economic evaluation of a digital health intervention for preventing dementia in Canadians with mild cognitive impairment. Frontiers in Public Health. 2025. doi:10.3389/fpubh.2025.1631676. PMID: 41048307.
BibTeX
@article{fereshtehnejad2025-41048307,
author = {Fereshtehnejad, Seyed‐Mohammad and Keshavjee, Karim and Coyte, Peter Christopher},
title = {{Economic evaluation of a digital health intervention for preventing dementia in Canadians with mild cognitive impairment}},
journal = {Frontiers in Public Health},
year = {2025},
doi = {10.3389/fpubh.2025.1631676},
pmid = {41048307},
url = {https://doi.org/10.3389/fpubh.2025.1631676}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
Key findings
- Dementia poses an on-going Canadian challenge due to an aging population, with cases projected to rise significantly by 2050.
- The analysis revealed favorable incremental cost-effectiveness ratios (ICERs) well below conventional willingness-to-pay thresholds across all scenarios.
- Sensitivity analyses confirmed the robustness of these findings, underscoring the intervention's potential to cost-effectively reduce dementia burden.
- Yet, these results provide valuable insights for Canadian policymakers on scalable, proactive dementia prevention strategies.
Why it matters
This exploratory, conceptual economic analysis found that a digital health intervention for people with mild cognitive impairment could be cost-effective for preventing dementia in Canada. The authors state the findings are based on modeled assumptions without empirical efficacy data, so they should be interpreted with caution until validated in real-world settings.
New to this subject? Start with our plain-English guide: Digital health →
Study details
- Evidence strengthLow
How this study scored 36/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomized / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Frontiers in Public Health) |
| Journal's citation record | 2 / 4 | Frontiers in Public Health: journal h-index 174 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomized / blinded | 0 / 2 | No randomization or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 1 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.3 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 1 / 6 | Cited 1.0× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 1 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Peter C. Coyte: h-index 62 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | University of Toronto: institution h-index 1,923 (OpenAlex) |
| Multicenter collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 2 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 41048307) |
| Free to read | 2 / 2 | Free to read |
| Total | 36 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.3389/fpubh.2025.1631676
- PubMed: 41048307
- Original source →
- Free full text: Frontiers in Public Health →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Related
Studies in the library that share something with this one. The line above each title says what.
Studies this one cites
Referenced by this study and also in the alzhub library, so you can read them here.
Related studies in Digital health tools
Also tagged “mini-mental”
840 studies in the library carry the topic tag “mini-mental”; these are this study's neighbours in a fixed, alphabetical-by-hash tour of them, not the closest in content. All 840 tagged studies.