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A systematic literature review and meta-analysis on digital health interventions for people living with dementia and Mild Cognitive Impairment
Di Lorito C, Bosco A, Rai H, Craven M, McNally D, Todd C, Booth V, Cowley A et al.. International journal of geriatric psychiatry, 2022-06-01
Topic: Risk, prevention and care in population studies
Plain-language summary
Objectives Digital health interventions enable services to support people living with dementia and Mild Cognitive Impairment (MCI) remotely. This literature review gathers evidence on the effectiveness of digital health interventions on physical, cognitive, behavioural and psychological outcomes, and Activities of Daily Living in people living with dementia and MCI. Methods/design Searches, using nine databases, were run in November 2021. Two authors carried out study selection/appraisal using the Critical Appraisal Skills Programme checklist. Study characteristics were extracted through the Cochrane handbook for systematic reviews of interventions data extraction form. Data on digital health interventions were extracted through the template for intervention description and replication (TIDieR) checklist and guide. Intervention effectiveness was determined through effect sizes. Meta-analyses were performed to pool data on intervention effectiveness. Results Twenty studies were included in the review, with a diverse range of interventions, modes of delivery, activities, duration, length, frequency, and intensity. Compared to controls, the interventions produced a moderate effect on cognitive abilities (SMD = 0.36; 95% CI = -0.03 to 0.76; I 2 = 61%), and a negative moderate effect on basic ADLs (SMD = -0.40; 95% CI = -0.86 to 0.05; I 2 = 69%). Stepping exergames generated the largest effect sizes on physical and cognitive abilities. Supervised training produced larger effect sizes than unsupervised interventions. Conclusion Supervised intervention delivery is linked to greatest benefits. A mix of remote and face-to-face delivery could maximise benefits and optimise costs. Accessibility, acceptability and sustainability of digital interventions for end-users must be pre-requisites for the development of future successful services.
What this study adds
Evidence grade: High
This is a pooled review. This meta-analysis of digital health interventions found a moderate effect on cognitive abilities and a negative moderate effect on basic activities of daily living, with confidence intervals crossing zero. It addresses remote support interventions and does not report a cure or prevention for Alzheimer's disease.
Taken from this record’s own fields, not from reading the paper. The grade is assigned from the abstract’s wording; what that means.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Di Lorito, C., Bosco, A., Rai, H., Craven, M., McNally, D., Todd, C., et al. (2022). A systematic literature review and meta-analysis on digital health interventions for people living with dementia and Mild Cognitive Impairment. International journal of geriatric psychiatry. https://doi.org/10.1002/gps.5730
Vancouver
Di Lorito C, Bosco A, Rai H, Craven M, McNally D, Todd C, et al. A systematic literature review and meta-analysis on digital health interventions for people living with dementia and Mild Cognitive Impairment. International journal of geriatric psychiatry. 2022. doi:10.1002/gps.5730. PMID: 35588315.
BibTeX
@article{dilorito2022-35588315,
author = {Di Lorito, C. and Bosco, A. and Rai, H. and Craven, M. and McNally, D. and Todd, C. and Booth, V. and Cowley, A. and others},
title = {{A systematic literature review and meta-analysis on digital health interventions for people living with dementia and Mild Cognitive Impairment}},
journal = {International journal of geriatric psychiatry},
year = {2022},
doi = {10.1002/gps.5730},
pmid = {35588315},
url = {https://doi.org/10.1002/gps.5730}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
Key findings
- Results Twenty studies were included in the review, with a diverse range of interventions, modes of delivery, activities, duration, length, frequency, and intensity.
- Compared to controls, the interventions produced a moderate effect on cognitive abilities (SMD = 0.36; 95% CI = -0.03 to 0.76; I 2 = 61%), and a negative moderate effect on basic ADLs (SMD = -0.40; 95% CI = -0.86 to 0.05; I 2 = 69%).
Why it matters
This meta-analysis of digital health interventions found a moderate effect on cognitive abilities and a negative moderate effect on basic activities of daily living, with confidence intervals crossing zero. It addresses remote support interventions and does not report a cure or prevention for Alzheimer's disease.
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Study details
- Study designmeta-analysis
- Evidence strengthHigh
How this study scored 63/100
Published in a peer-reviewed journal, and it is a meta-analysis pooling many studies. Scored zero for sample size, effect reported and studied in people because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (International journal of geriatric psychiatry) |
| Journal's citation record | 2 / 4 | International Journal of Geriatric Psychiatry: journal h-index 190 (OpenAlex, 2026-10-29) |
| Study design | 12 / 12 | A meta-analysis pooling many studies |
| Strength of evidence | 5 / 5 | Rated “high” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 3 / 5 | 2022 — within 6 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomized / blinded | 0 / 2 | A review of other studies — randomization is not credited here |
| Times cited | 4 / 7 | Cited 62 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 10.3 citations a year over 6 year(s) since 2022 |
| Impact for its field and year | 2 / 6 | Cited 2.6× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 3 other studies in this library |
| Still being cited | 3 / 4 | Cited 52 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Rowan Harwood: h-index 50 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | University of Manchester: institution h-index 1,304 (OpenAlex) |
| Multicenter collaboration | 2 / 3 | OpenAlex lists 6 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 35588315) |
| Free to read | 2 / 2 | Free to read |
| Total | 63 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1002/gps.5730
- PubMed: 35588315
- Original source →
- Free full text: International Journal of Geriatric Psychiatry →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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