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67/100

✓ Peer-reviewed alzhub usefulness score 67 out of 100. Digital health tools

Topic: Amyloid, tau and blood-test diagnosis

Despite the promise of a multitude of sensors and devices that can be applied, there are no agreed-upon standards for digital biomarkers, nor are there comprehensive evidence-based results for which digital biomarkers may be demonstrated to be most effective. Results An initial sample of 4811 English-language papers were retrieved. Evidence available from embedded passive sensors represents the most relatively mature research area, suggesting that some of these solutions could be proposed to larger populations in the coming decade.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Piau, A., Wild, K., Mattek, N., & Kaye, J. (2019). Current State of Digital Biomarker Technologies for Real-Life, Home-Based Monitoring of Cognitive Function for Mild Cognitive Impairment to Mild Alzheimer Disease and Implications for Clinical Care: Systematic Review. Journal of medical Internet research. https://doi.org/10.2196/12785

Vancouver

Piau A, Wild K, Mattek N, Kaye J. Current State of Digital Biomarker Technologies for Real-Life, Home-Based Monitoring of Cognitive Function for Mild Cognitive Impairment to Mild Alzheimer Disease and Implications for Clinical Care: Systematic Review. Journal of medical Internet research. 2019. doi:10.2196/12785. PMID: 31471958.

BibTeX

@article{piau2019-31471958,
  author  = {Piau, A. and Wild, K. and Mattek, N. and Kaye, J.},
  title   = {{Current State of Digital Biomarker Technologies for Real-Life, Home-Based Monitoring of Cognitive Function for Mild Cognitive Impairment to Mild Alzheimer Disease and Implications for Clinical Care: Systematic Review}},
  journal = {Journal of medical Internet research},
  year    = {2019},
  doi     = {10.2196/12785},
  pmid    = {31471958},
  url     = {https://doi.org/10.2196/12785}
}

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Key findings

Despite the promise of a multitude of sensors and devices that can be applied, there are no agreed-upon standards for digital biomarkers, nor are there comprehensive evidence-based results for which digital biomarkers may be demonstrated to be most effective.
Results An initial sample of 4811 English-language papers were retrieved.
Evidence available from embedded passive sensors represents the most relatively mature research area, suggesting that some of these solutions could be proposed to larger populations in the coming decade.

Why it matters

There are currently no agreed-upon standards for digital biomarkers, and no comprehensive evidence showing which ones work best for monitoring cognitive function at home. Embedded passive sensors are the most mature area of research, and some of these solutions could be offered to larger populations in the coming decade.

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Study details

Participants279
Evidence strengthLow

How this study scored 67/100

Published in a peer-reviewed journal, and it is a systematic review of all the studies on the question. Scored zero for effect reported because the record does not state it.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Journal of medical Internet research)
Journal's citation record	3 / 4	Journal of Medical Internet Research: journal h-index 286 (OpenAlex, 2026-10-29)
Study design	12 / 12	A systematic review of all the studies on the question (from PubMed type “Systematic Review”)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	2 / 5	2019 — within 10 year(s) of the newest study here
Sample size	2 / 4	279 participants
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	3 / 3	Studied in people (participant count stated)
Randomised / blinded	0 / 2	A review of other studies — randomisation is not credited here
Times cited	5 / 7	Cited 250 times (OpenAlex, 2026-10-10)
Citations per year	4 / 5	27.8 citations a year over 9 year(s) since 2019
Impact for its field and year	3 / 6	Cited 3.9× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	2 / 6	Cited by 8 other studies in this library
Still being cited	3 / 4	Cited 132 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	4 / 4	Last-listed author Jeffrey Alan Kaye: h-index 122 (OpenAlex, whole career)
Institution's track record	1 / 3	Oregon Health & Science University: institution h-index 1,025 (OpenAlex)
Multi-centre collaboration	1 / 3	OpenAlex lists 2 institution(s) in 2 countries
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 31471958)
Free to read	2 / 2	Free to read
Total	67 / 100	—

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