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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26889 of the 27780 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 27,401–27,425 of 27,780 studies, newest first · page 1097 of 1112.

September 1990 2

  1. 1990-09-01

    The amyloid precursor protein of Alzheimer's disease is released by human platelets

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: These species were similar in size to forms seen in brain preparations and in plasma. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1990-09-01

    Involvement of free radicals in dementia of the Alzheimer type: a hypothesis

    ✓ Peer-reviewed Prevention and risk Neurobiology of aging

    Key finding: There is some evidence for increased free radical formation in Down's syndrome which is associated with development of DAT pathology. +1 more finding

    Full summary, score breakdown and related studies → Original source

August 1990 7

  1. 1990-08-01

    Cytochrome oxidase deficiency in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Neurology

    Key finding: Other electron transport chain catalytic activities were not significantly different than control values.

    Full summary, score breakdown and related studies → Original source

  2. 1990-08-01

    Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease

    ✓ Peer-reviewed Health systems and care delivery The American journal of psychiatry

    Key finding: These results suggest that potentially treatable (noncognitive) behavioral and psychiatric symptoms are risk factors for institutionalization, and that treating these symptoms might delay or prevent institutionalization of some patients.

    Full summary, score breakdown and related studies → Original source

  3. 1990-08-01

    Large amounts of neocortical beta A4 deposits without neuritic plaques nor tangles in a psychometrically assessed, non-demented person

    ✓ Peer-reviewed Drug development Neuroscience letters

    Key finding: These data indicate that severe diffuse beta A4 deposits in the neocortex do not induce dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 1990-08-01

    Evolution of spatial cognition: sex-specific patterns of spatial behavior predict hippocampal size

    ✓ Peer-reviewed Hippocampus size on brain scans Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Our controlled comparison suggests that evolution can produce adaptive sex differences in behavior and its neural substrate.

    Full summary, score breakdown and related studies → Original source

  5. 1990-08-01

    Longitudinal evaluation of dementia of the Alzheimer type: a comparison of 3 standardized mental status examinations

    ✓ Peer-reviewed Cognitive tests and assessment Neurology

    Key finding: The 3 tests were readministered to 55 of the patients (2-year subgroup) approximately 1 year later, and administered a 3rd time to 20 of the patients (3-year subgroup) approximately 2 years after their initial assessment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1990-08-01

    Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

    ✓ Peer-reviewed Risk genes beyond APOE Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Phorbol 12,13-dibutyrate, an agent that stimulates protein kinase C, decreased the levels of mature beta APP and increased the levels of 15- and 19-kDa peptides. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1990-08-01

    Neuronal plasticity and astrocytic reaction in Down syndrome and Alzheimer disease

    ✓ Peer-reviewed Biomarkers Journal of the neurological sciences

    Key finding: The observations (normal GS and elevated levels of the other markers) might suggest that the pathological changes involve a differentiated astrocytic reaction and that the astrocytic reaction is more marked in DS than in AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

July 1990 7

  1. 1990-07 month only

    DGAVP (Org 5667) in early Alzheimer's disease patients: an international double-blind, placebo-controlled, multicenter trial

    ✓ Peer-reviewed Clinical trials Neurology

    Key finding: Neither clinical rating scales nor psychometric tests revealed any improvement over 84 days with once-daily intranasal treatment with 2 different doses of DGAVP. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 1990-07-01

    Psychiatric phenomena in Alzheimer's disease. IV: Disorders of behaviour

    ✓ Peer-reviewed Clinical safety The British journal of psychiatry : the journal of mental science

    Key finding: Out of a sample of 178 patients with AD, aggression was present in 20%, wandering in 19%, binge-eating in 10%, hyperorality in 6%, urinary incontinence in 48%, and sexual disinhibition in 7%. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1990-07-01

    Reactive microglia express class I and class II major histocompatibility complex antigens in Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Brain research

    Key finding: Monoclonal antibodies to class I antigens stained reactive microglia weakly to moderately and vascular endothelial cells strongly in Alzheimer's gray and white matter. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1990-07-01

    Brain atrophy in 18 patients with Down syndrome: a CT study

    ✓ Peer-reviewed Down syndrome and Alzheimer's AJNR. American journal of neuroradiology

    Key finding: We compared CT scans of 18 Down syndrome subjects, 26-70 years old (seven of whom satisfied criteria for dementia), with 175 screened normal volunteer control subjects for evidence of cortical and subcortical atrophy. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1990-07-01

    Comprehension of prosody in Huntington's disease

    ✓ Peer-reviewed Digital health tools Journal of neurology, neurosurgery, and psychiatry

    Key finding: Patients with Huntington's Disease (HD) who were without dementia were compared to unilateral stroke patients and controls as previously reported in 1983, to discover if they had a prosodic defect. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1990-07-01

    Selegiline in the treatment of mild to moderate Alzheimer-type dementia

    ✓ Peer-reviewed Treatments Clinical therapeutics

    Key finding: Its efficacy and tolerability were compared with that of phosphatidylserine in a randomized, single-blind, parallel fashion. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 1990-07-01

    Ammonia induced decrease in glial fibrillary acidic protein in cultured astrocytes

    ✓ Peer-reviewed Biomarkers Journal of neuropathology and experimental neurology

    Key finding: Previous studies of human hepatic encephalopathy (HE) have shown decreased levels of glial fibrillary acidic protein (GFAP) in Alzheimer type II astrocytes. +3 more findings

    Full summary, score breakdown and related studies → Original source

June 1990 6

  1. 1990-06-01

    Amyloid beta protein precursor gene and hereditary cerebral hemorrhage with amyloidosis (Dutch)

    ✓ Peer-reviewed Down syndrome and Alzheimer's Science (New York, N.Y.)

    Key finding: Immunohistochemical and biochemical studies have indicated that the amyloid subunit in HCHWA-D is antigenically related to and homologous in sequence with the amyloid beta protein isolated from brains of patients with Alzheimer's disease and Down syndrome. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 1990-06-01

    Effect of antibiotic treatment on outcome of fevers in institutionalized Alzheimer patients

    ✓ Peer-reviewed End-of-life care JAMA

    Key finding: Patients who received diagnostic workup of all fevers and treatment with antibiotics (Antibiotic Group) were compared with patients who received comfort measures only (Palliative Group). +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1990-06-01

    Cleavage of amyloid beta peptide during constitutive processing of its precursor

    ✓ Peer-reviewed Risk genes beyond APOE Science (New York, N.Y.)

    Key finding: Abundant A beta P deposition in the brains of patients with Alzheimer's disease suggests that altered APP processing may represent a key pathogenic event. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 1990-06-01

    Mutation of the Alzheimer's Disease Amyloid Gene in Hereditary Cerebral Hemorrhage, Dutch Type

    ✓ Peer-reviewed Risk genes beyond APOE Science

    An amyloid protein that precipitates in the cerebral vessel walls of Dutch patients with hereditary cerebral hemorrhage with amyloidosis is similar to the amyloid protein in vessel walls and senile plaques in brains of patients with Alzheimer's disease, Down syndrome, and sporadic cerebral amyloid angiopathy.

    Full summary, score breakdown and related studies → Original source

  5. 1990-06-01

    Platelet coagulation factor XIa-inhibitor, a form of Alzheimer amyloid precursor protein

    ✓ Peer-reviewed Risk genes beyond APOE Science (New York, N.Y.)

    Key finding: Platelets stimulated with thrombin or calcium ionophore (A23187) secrete a protein functionally and immunologically identical to the inhibitor, implying a role for this inhibitor in hemostasis. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1990-06-01

    Autoimmune thyroiditis associated with mild "subclinical" hypothyroidism in adults with Down syndrome: a comparison of patients with and without manifestations of Alzheimer disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's American journal of medical genetics

    Key finding: Relative to control individuals, DS patients had, overall, lower mean total T4 (P = 0.070) and T3f (P = 0.015), higher T3U (P = 0.013) and TSH (P = 0.020), no difference in free T4, and higher thyroid antithyroglobulin (ATA) (P = 0.033) and antimicrosomal autoantibody (AMA) titres (P = 0.0097). +3 more findings

    Full summary, score breakdown and related studies → Original source

May 1990 3

  1. 1990-05-01

    Protease nexin-II (amyloid beta-protein precursor): a platelet alpha-granule protein

    ✓ Peer-reviewed Down syndrome and Alzheimer's Science (New York, N.Y.)

    Key finding: Because PN-II/APP is a potent protease inhibitor and possesses growth factor activity, these results implicate PN-II/APP in wound repair.

    Full summary, score breakdown and related studies → Original source

  2. 1990-05-01

    The aging of America. Impact on health care costs

    ✓ Peer-reviewed Health systems and care delivery JAMA

    Key finding: Without major changes in the health of our older population, these health care costs will escalate enormously, in large part as a result of the projected growth of the "oldest old," those aged 85 years and above.

    Full summary, score breakdown and related studies → Original source

  3. 1990-05-01

    A metaanalysis of controlled trials of neuroleptic treatment in dementia

    ✓ Peer-reviewed Clinical trials Journal of the American Geriatrics Society

    Key finding: Prior qualitative literature reviews about the use of neuroleptics in dementia suggest that they are "modestly effective" in treating agitation and that no single neuroleptic is better than another. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →