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Newest in this topic

  1. Pathway-specific polygenic risk scores reveal underlying mechanisms of cerebral small vessel disease 2026-09-14
  2. Cerebral Small Vessel Disease and Risk of Cardiovascular Events and All-Cause Mortality: The Framingham Heart Study 2026-09-07
  3. Regional Distribution of Mineralized Blood Vessels in Alzheimer Disease and Clinicopathological Associations: A Multicenter Autopsy Study 2026-09-01

Studies

904 studies carry this tag.

Date range

1975 to 2026

Top journals

  • Neurology 93
  • Stroke 61
  • Alzheimer s & Dementia 31
  • Brain : a journal of neurology 20
  • Annals of neurology 19

342 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Vascular Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Circulation research 2017-02-01 Brain scans and imaging

    Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both.

  2. Finding the imposter: brain connectivity of lesions causing delusional misidentifications

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. Brain : a journal of neurology 2017-01-12 Clinical safety

    SEE MCKAY AND FURL DOI101093/AWW323 FOR A SCIENTIFIC COMMENTARY ON THIS ARTICLE: Focal brain injury can sometimes lead to bizarre symptoms, such as the delusion that a family member has been replaced by an imposter (Capgras syndrome).

  3. Imaging retina to study dementia and stroke

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Progress in retinal and eye research 2017-01-03 Vascular contributions

    With increase in life expectancy, the number of persons suffering from common age-related brain diseases, including neurodegenerative (e.g., dementia) and cerebrovascular (e.g., stroke) disease is expected to rise substantially.

  4. The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic orthostatic hypotension and associated supine hypertension

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Journal of neurology 2017-01-03 Getting a diagnosis

    Neurogenic orthostatic hypotension (nOH) is common in patients with neurodegenerative disorders such as Parkinson's disease, multiple system atrophy, pure autonomic failure, dementia with Lewy bodies, and peripheral neuropathies including amyloid or diabetic neuropathy.

  5. Higher arterial stiffness and pulsatility were associated with MCI and dementia in white participants.

  6. Plasma Amyloid-β Levels, Cerebral Small Vessel Disease, and Cognition: The Rotterdam Study

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Long-term cohort studies

    Plasma amyloid-β (Aβ) levels are increasingly studied as a potential, accessible marker of cognitive impairment and dementia.

  7. Two decades of epidemiological research shows that silent cerebrovascular disease is common and is associated with future risk for stroke and dementia.

  8. Cerebral blood flow measured by arterial spin labeling MRI at resting state in normal aging and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Neuroscience and biobehavioral reviews 2016-11-28 Mild cognitive impairment

    Arterial spin labeling (ASL) magnetic resonance imaging uses arterial blood water as an endogenous tracer to measure cerebral blood flow (CBF).

  9. Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. The Journal of clinical investigation 2016-11-14 Risk factors

    Hypertension is a leading risk factor for dementia, but the mechanisms underlying its damaging effects on the brain are poorly understood.

  10. Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Experimental gerontology 2016-11-12 Inflammation and the immune system

    The importance of (micro)vascular contributions to cognitive impairment and dementia (VCID) in aging cannot be overemphasized, and the pathogenesis and prevention of age-related cerebromicrovascular pathologies are a subject of intensive research.

  11. Vascular depression consensus report - a critical update

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. BMC medicine 2016-11-03 Brain scans and imaging

    This diagnosis, based on clinical and MRI findings, suggests that vascular lesions lead to depression by disruption of frontal-subcortical-limbic networks involved in mood regulation.

  12. Arterial Spin Labeling Perfusion of the Brain: Emerging Clinical Applications

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Radiology 2016-11-01 Vascular contributions

    Arterial spin labeling (ASL) is a magnetic resonance (MR) imaging technique used to assess cerebral blood flow noninvasively by magnetically labeling inflowing blood.

  13. Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. American journal of physiology. Heart and circulatory physiology 2016-10-28 Inflammation and the immune system

    Increasing evidence from epidemiological, clinical and experimental studies indicate that age-related cerebromicrovascular dysfunction and microcirculatory damage play critical roles in the pathogenesis of many types of dementia in the elderly, including Alzheimer's disease.

  14. Association Between Life's Simple 7 and Noncardiovascular Disease: The Multi-Ethnic Study of Atherosclerosis

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Journal of the American Heart Association 2016-10-20 Prevention and risk

    The American Heart Association's LS7 score identified individuals who were vulnerable to multiple chronic nonvascular conditions.

  15. Shining light on the head: Photobiomodulation for brain disorders

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. BBA clinical 2016-10-01 Vascular contributions

    Photobiomodulation (PBM) describes the use of red or near-infrared light to stimulate, heal, regenerate, and protect tissue that has either been injured, is degenerating, or else is at risk of dying.

  16. Neurological Disease as a Failure of Brain-Immune Crosstalk: The Multiple Faces of Neuroinflammation

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. Trends in immunology 2016-09-06 Inflammation and the immune system

    Neuroinflammation is common to various diseases of the central nervous system (CNS), but its imprecise definition has led to many misconceptions in research and clinical approaches.

  17. Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. JAMA neurology 2016-09-01 How common it is

    Pooled clinical and neuropathologic data from 3 prospective cohort studies indicate that TBI with LOC is associated with risk for Lewy body accumulation, progression of parkinsonism, and PD, but not dementia, AD, neuritic plaques, or neurofibrillary tangles.

  18. Stroke, Vascular Dementia, and Alzheimer's Disease: Molecular Links

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of Alzheimer's disease : JAD 2016-09-01 Prevention and risk

    Stroke is a brain disease that occurs when blood flow stops, resulting in reduced oxygen supply to neurons.

  19. Update on cerebral small vessel disease: a dynamic whole-brain disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Stroke and vascular neurology 2016-09-01 Getting a diagnosis

    Cerebral small vessel disease (CSVD) is a very common neurological disease in older people.

  20. Healthy brain connectivity predicts atrophy progression in non-fluent variant of primary progressive aphasia

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Brain : a journal of neurology 2016-08-06 Digital health tools

    Graph theoretical analysis of the speech/language network showed that regions with shorter functional paths to the epicentre exhibited greater longitudinal atrophy.

  21. Cerebral blood flow in small vessel disease: A systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 73 out of 100. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2016-08-05 Getting a diagnosis

    White matter hyperintensities are frequent on neuroimaging of older people and are a key feature of cerebral small vessel disease.

  22. Brain Insulin Resistance at the Crossroads of Metabolic and Cognitive Disorders in Humans

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Physiological reviews 2016-08-03 Risk factors

    Ever since the brain was identified as an insulin-sensitive organ, evidence has rapidly accumulated that insulin action in the brain produces multiple behavioral and metabolic effects, influencing eating behavior, peripheral metabolism, and cognition.

  23. Inflammasomes link vascular disease with neuroinflammation and brain disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2016-08-02 Inflammation and the immune system

    The role of inflammation in neurological disorders is increasingly recognised.

  24. Association of Cerebral Microbleeds With Cognitive Decline and Dementia

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. JAMA neurology 2016-08-01 How common it is

    Microbleed prevalence was 15.3% (median [interquartile range] count, 1 [1-88]).

  25. How neuroinflammation contributes to neurodegeneration

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Science (New York, N.Y.) 2016-08-01 Lewy body dementia

    Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and frontotemporal lobar dementia are among the most pressing problems of developed societies with aging populations.

  26. At-home tDCS of the left dorsolateral prefrontal cortex improves visual short-term memory in mild vascular dementia

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Journal of the neurological sciences 2016-07-30 Prevention trials

    In patients with mild vascular dementia, anodal tDCS of the left DLPFC is able to produce additional effects to cognitive training on visual short-term memory, verbal working memory, and executive control.

  27. Neurodegenerative and neurological disorders by small inhaled particles

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Neurotoxicology 2016-07-19 Inflammation and the immune system

    The world's population is steadily ageing and as a result, health conditions related to ageing, such as dementia, have become a major public health concern.

  28. Prestroke Vascular Pathology and the Risk of Recurrent Stroke and Poststroke Dementia

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Stroke 2016-07-14 Long-term cohort studies

    Improved short-term survival after stroke has necessitated quantifying risk and risk factors of long-term sequelae after stroke (ie, recurrent stroke and dementia).

  29. Sleep Apnea, Sleep Duration and Brain MRI Markers of Cerebral Vascular Disease and Alzheimer's Disease: The Atherosclerosis Risk in Communities Study (ARIC)

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. PloS one 2016-07-14 Long-term cohort studies

    A growing body of literature has suggested that obstructive sleep apnea (OSA) and habitual short sleep duration are linked to poor cognitive function.

  30. Cerebral hypoperfusion and glucose hypometabolism: Key pathophysiological modulators promote neurodegeneration, cognitive impairment, and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of neuroscience research 2016-06-27 Risk factors

    There is significant evidence that pathways involving inflammation and oxidative-nitrosative stress (ONS) play a key pathophysiological role in promoting cognitive dysfunction.

  31. Lower cerebral blood flow is associated with faster cognitive decline in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. European radiology 2016-06-22 Cognitive tests and assessment

    We included 88 patients with dementia due to AD from the Amsterdam Dementia Cohort.

  32. Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. The Lancet. Neurology 2016-06-14 How common it is

    Each level increase in the severity of atherosclerosis or arteriolosclerosis was associated with significantly higher odds of Alzheimer's disease dementia (odds ratio [OR] for atherosclerosis 1·33, 95% CI 1·11-1·58; OR for arteriolosclerosis 1·20, 1·04-1·40).

  33. Pathophysiological Role of Neuroinflammation in Neurodegenerative Diseases and Psychiatric Disorders

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. International neurourology journal 2016-05-26 Inflammation and the immune system

    Brain diseases and disorders such as Alzheimer disease, Parkinson disease, depression, schizophrenia, autism, and addiction lead to reduced quality of daily life through abnormal thoughts, perceptions, emotional states, and behavior.

  34. "New Old Pathologies": AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS)

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Journal of neuropathology and experimental neurology 2016-05-21 Disease mechanisms

    The pathology-based classification of Alzheimer's disease (AD) and other neurodegenerative diseases is a work in progress that is important for both clinicians and basic scientists.

  35. Molecular Mechanisms of Vascular Dementia: What Can Be Learned from Animal Models of Chronic Cerebral Hypoperfusion?

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Molecular neurobiology 2016-05-20 Inflammation and the immune system

    Vascular dementia (VD) is defined as a progressive neurodegenerative disease of cognitive decline, attributable to cerebrovascular factors.

  36. Developing Brain Vital Signs: Initial Framework for Monitoring Brain Function Changes Over Time

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Frontiers in neuroscience 2016-05-12 Digital health tools

    Clinical assessment of brain function relies heavily on indirect behavior-based tests.

  37. Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. The Lancet. Neurology 2016-05-11 Long-term cohort studies

    We postulated that cerebral amyloid angiopathy (CAA), characterised by cortical vascular amyloid deposits, is associated with cortical tissue loss independent of parenchymal Alzheimer's disease pathology.

  38. Brain in Congenital Heart Disease Across the Lifespan: The Cumulative Burden of Injury

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Circulation 2016-05-01 Caregiving

    The number of patients surviving with congenital heart disease (CHD) has soared over the last 3 decades.

  39. Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Stroke 2016-04-12 Long-term cohort studies

    The American Heart Association developed the ideal cardiovascular health (CVH) index as a simple tool to promote CVH; yet, its association with brain atrophy and dementia remains unexamined.

  40. Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Acta neuropathologica 2016-04-09 Getting a diagnosis

    Vascular dementia (VaD) is recognised as a neurocognitive disorder, which is explained by numerous vascular causes in the general absence of other pathologies.

  41. The prevalence of ICAS in older adults is high, and it could be a target for primary prevention of stroke and dementia in this population.

  42. The role of glial-specific Kir4.1 in normal and pathological states of the CNS

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Acta neuropathologica 2016-03-09 Inflammation and the immune system

    Kir4.1 is an inwardly rectifying K(+) channel expressed exclusively in glial cells in the central nervous system.

  43. The Science of Vascular Contributions to Cognitive Impairment and Dementia (VCID): A Framework for Advancing Research Priorities in the Cerebrovascular Biology of Cognitive Decline

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Cellular and molecular neurobiology 2016-03-01 Caregiving

    The World Health Organization reports that 47.5 million people are affected by dementia worldwide.

  44. Role of neuroinflammation in neurodegenerative diseases (Review)

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Molecular medicine reports 2016-02-29 Inflammation and the immune system

    Neurodegeneration is a phenomenon that occurs in the central nervous system through the hallmarks associating the loss of neuronal structure and function.

  45. Neural substrates of vulnerability to postsurgical delirium as revealed by presurgical diffusion MRI

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Brain : a journal of neurology 2016-02-26 Clinical safety

    Despite the significant impact of postoperative delirium on surgical outcomes and the long-term prognosis of older patients, its neural basis has not yet been clarified.

  46. White matter hyperintensities and imaging patterns of brain ageing in the general population

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Brain : a journal of neurology 2016-02-24 Caregiving

    White matter hyperintensities are associated with increased risk of dementia and cognitive decline.

  47. Heterogeneous histopathology of cortical microbleeds in cerebral amyloid angiopathy

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Neurology 2016-02-03 Brain scans and imaging

    This study provides evidence for heterogeneous pathologic substrates and possibly different pathophysiologic mechanisms underlying MRI-observed cortical microbleeds in the context of advanced CAA and Alzheimer disease.

  48. Impaired Cognition and Brain Atrophy Decades After Hypertensive Pregnancy Disorders

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Circulation. Cardiovascular quality and outcomes 2016-02-01 Digital health tools

    Hypertensive pregnancy disorders are associated with worse performance on tests of processing speed and smaller brain volumes decades later.

  49. Stroke injury, cognitive impairment and vascular dementia

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Biochimica et biophysica acta 2016-01-22 Prevention and risk

    The global burden of ischaemic strokes is almost 4-fold greater than haemorrhagic strokes.

  50. Epidemiology of stroke and transient ischemic attacks: Current knowledge and perspectives

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Revue neurologique 2015-12-21 Prevention and risk

    Because of the growing size and aging of the world's population, the global burden of stroke is increasing dramatically.

From across this tag

9 of the 903 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.

All topic tags with their study counts