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small
904 studies tagged small, dated 1975-09-01 to 2026-09-14. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Pathway-specific polygenic risk scores reveal underlying mechanisms of cerebral small vessel disease 2026-09-14
- Cerebral Small Vessel Disease and Risk of Cardiovascular Events and All-Cause Mortality: The Framingham Heart Study 2026-09-07
- Regional Distribution of Mineralized Blood Vessels in Alzheimer Disease and Clinicopathological Associations: A Multicenter Autopsy Study 2026-09-01
Studies
904 studies carry this tag.
Date range
1975 to 2026
Top journals
- Neurology 93
- Stroke 61
- Alzheimer s & Dementia 31
- Brain : a journal of neurology 20
- Annals of neurology 19
342 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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We assessed the regional brain atrophy in mouse lemur primates from 4.7T T2-weighted magnetic resonance images.
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The white matter (WM) of the adult human neocortex contains the so-called "interstitial neurons".
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Cerebrovascular disease and Alzheimer disease are common diseases of aging and frequently coexist in the same brain.
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55/100
MRI evidence of small subacute infarcts is present in a substantial proportion of living patients with advanced cerebral amyloid angiopathy (CAA).
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Carotid atherosclerosis markers were associated with MRI indices of brain ischemia and aging and with cognitive impairment in a community-based sample of middle-aged adults.
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Our data suggest that vascular abnormalities, independently of blood pressure levels, may play a role in the setting of subjective memory complaints as well as of WMH in elderly hypertensive patients.
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The introduction of immunotherapy and its ultimate success will require re-evaluation of the pathogenesis of Alzheimer's disease particularly with regard to the role of the ageing microvasculature and the effects of APOE genotype.
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Cerebral microbleeds (CMBs) are increasingly recognised neuroimaging findings in individuals with cerebrovascular disease and dementia, and in normal ageing.
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46/100
FA reduction in forceps minor was the most significant area of difference between AD and VaD.
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The targeted brain dysfunction that accompanies aging can have a devastating effect on cognitive and intellectual abilities.
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48/100
Simple MRI biomarkers, in addition to their diagnostic use, have a prognostic value with respect to mortality in a memory clinic population.
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Initial recruitment of leukocytes in inflammation associated with diseases such as multiple sclerosis (MS), ischemic stroke, and HIV-related dementia, takes place across intact, but activated brain endothelium.
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Most strokes are covert and observed incidentally on brain scans, but their presence increases risk of overt stroke and dementia.
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The dietary essential PUFA docosahexaenoic acid [DHA; 22:6(n-3)] is a critical contributor to cell structure and function in the nervous system, and deficits in DHA abundance are associated with cognitive decline during aging and in neurodegenerative disease.
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The presence of burst suppression, which was unexpectedly high in this medical intensive care unit population, was an independent predictor of increased risk of death at 6 months.
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Lesions of the cerebral white matter (WM) result in focal neurobehavioral syndromes, neuropsychiatric phenomena, and dementia.
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55 of the 152 (36.2 %) aMCI subjects progressed to AD.
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Immobility-related complications are very common in the first year after a severely disabling stroke.
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53/100
Patterns of gray matter loss are associated with neurofibrillary tangle (NFT) pathology, specifically with NFT burden at Braak stages III and IV and with Braak stage itself at higher stages.
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All antipsychotics are associated with an increased risk of stroke, and the risk might be higher in patients receiving atypical antipsychotics than those receiving typical antipsychotics.
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64/100
Cerebral small vessel disease (SVD) is a major cause of stroke and dementia.
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57/100
Older age and vascular disease, particularly among African Americans, are associated with increased brain atrophy and WMH burden.
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AF contributes to stroke and secondary cognitive decline.
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We investigated the changes of sulcal shape (average mean curvature in folded regions and sulcal depth) in mild cognitive impairment (MCI) and Alzheimer's disease (AD) using quantitative surface-based methods in a large sample of magnetic resonance imaging data.
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Higher age, female sex, cigarette smoking, elevated blood pressure, and baseline lesion load were associated with small vessel disease progression.
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49/100
Increased total and periventricular (PV) white matter hyperintensity (WMH) burden and progression of PV WMH burden are associated with decreased gait performance over time, while progression of subcortical WMH volume is associated with memory decline in cognitively intact elderly.
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Cerebral ischaemia is a major cause of disability and death globally and has a profoundly negative impact on the individuals it affects, those that care for them and society as a whole.
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Essential hypertension has devastating effects on the brain, being the major cause of stroke and a leading cause of dementia.
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Occipital predominance of microbleeds with corresponding parietooccipital leukoaraiosis has not been well described in prior imaging studies of AD.
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The prevalence of idiopathic normal-pressure hydrocephalus (NPH) in a community was investigated by retrospective analysis of data from a previous community-based study of 170 randomly selected elderly residents aged 65 years or older.
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The risk of vascular or mixed dementia, but not of other types of dementia, was significantly increased in MCI patients with a large amount of subcortical hyperintensities at baseline.
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57/100
Men, but not women, with unrecognized myocardial infarction (MI) have an increased risk of cardiac events and stroke compared with those without MI or with recognized MI.
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Vascular cognitive impairment (VCI) comprises a range of cognitive disorders related to cerebral vessel disease and has generally replaced the term multi-infarct dementia.
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47/100
Cognitively normal subjects with HTN (n=19) had decreased rCBF in the putamen, globus pallidus, bilaterally, and in the left hippocampus compared with normotensives (n=22).
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Cross-sectional and longitudinal observation.
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Diffusion tensor imaging (DTI) has become one of the most popular MRI techniques in brain research, as well as in clinical practice.
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High WMH was a predictor of progression from normal to MCI (adjusted hazard ratio [HR], 3.30; 95% confidence interval [CI], 1.33-8.17; P= .01) but not conversion from MCI to all-cause dementia.
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36/100
The review focuses on the clinical diagnostic utility of transcranial magnetic stimulation (TMS).
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Transient neurological attacks (TNAs) are attacks with temporary ( Objective To study the incidence and prognosis of focal TNAs (or TIAs), nonfocal TNAs, and mixed TNAs.
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In this group of older adults free from neurodegenerative diseases, a greater variability of step length was associated with greater burden of subclinical brain vascular abnormalities as defined by MRI.
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The PLI performed at least as well as the PC in detecting true changes in synchronization in model and real data but, at the same token and like-wise the IC, it was much less affected by the influence of common sources and active reference electrodes.
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The association between moderate-severe chronic kidney disease and white matter hyperintensity volume highlights the growing importance of kidney disease as a possible determinant of cerebrovascular disease and/or as a marker of microangiopathy.
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Brain vasculature is a complex and interconnected network under tight regulatory control that exists in intimate communication with neurons and glia.
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Our results suggest that genes associated with clinical neurological disease also have detectable effects on subclinical phenotypes.
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Cerebral "microvascular" disease occurs in lacunar stroke, leukoaraiosis, vascular dementia and Alzheimer's disease.
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As the availability and quality of imaging techniques improve, doctors are identifying more patients with no history of transient ischaemic attack or stroke in whom imaging shows brain infarcts.
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Cerebral white matter hyperintensities on brain MRI (leukoaraiosis) are associated with increased risk of stroke and dementia.
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Cognitive impairment is common in the first weeks after stroke, with executive and perceptual disorders being the most frequent.
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Baseline MRI scans were characterized by asymmetric T2-hyperintense lesions extending to the subcortical white matter and occasionally the overlying gray matter, with signal properties suggesting vasogenic edema.
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Systemic inflammation is associated with ischemia and Alzheimer disease (AD).
From across this tag
8 of the 903 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 8. The same 8 appear here every time.
- Arterial Spin Labeling Perfusion of the Brain: Emerging Clinical Applications
- Vascular Cognitive Impairment (VCI)
- Cerebral Small Vessel Disease, Hypertension, and Vascular Contributions to Cognitive Impairment and Dementia
- Cerebral Small Vessel Disease
- Blood-Brain Barrier Disruption Is an Early Event That May Persist for Many Years After Traumatic Brain Injury in Humans
- High-Dimensional Single-Cell Multimodal Landscape of Human Carotid Atherosclerosis
- Human brain connectivity: Clinical applications for clinical neurophysiology
- Unifying Vascular Injury and Neurodegeneration: A Mechanistic Continuum in Cerebral Small Vessel Disease and Dementia