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Home › Research › Topics › pet

pet

1,161 studies tagged pet, dated 1983-08-01 to 2026-11-01. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Large-scale head-to-head comparison of on- and off-target profiles of [18F]Tauvid and [18F]MK6240 tau-PET in aging and Alzheimer’s disease 2026-11-01
  2. Detection of tau spatial extent using MK6240 and flortaucipir PET 2026-10-28
  3. Soluble amyloid composition links proximal APP processing, fibrillar burden and the p-tau181 response 2026-10-22

Studies

1,161 studies carry this tag.

Date range

1983 to 2026

Top journals

  • Neurology 88
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 57
  • Brain : a journal of neurology 52
  • Journal of nuclear medicine : official publication, Society of Nuclear Medicine 51
  • Alzheimer's research & therapy 34

337 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Change in rates of cerebral atrophy over time in early-onset Alzheimer's disease: longitudinal MRI study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Lancet (London, England) 2003-10-01 Cognitive tests and assessment

    The extent to which cerebral atrophy in Alzheimer's disease changes with time is unknown.

  2. Changes in premorbid brain volume predict Alzheimer's disease pathology

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Neurology 2003-08-01 Brain scans and imaging

    MRI volumes measured over time are valid biomarkers of pathologic progression of AD across a range of antemortem clinical states.

  3. Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. European journal of nuclear medicine and molecular imaging 2003-05-23 Mild cognitive impairment

    A high percentage of patients with mild cognitive impairment (MCI) develop clinical dementia of the Alzheimer type (AD) within 1 year.

  4. Neuroimaging in Alzheimer disease: an evidence-based review

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Neuroimaging clinics of North America 2003-05-01 Genetics

    Neuroimaging is valuable in predicting future development of AD in patients with MCI and in carriers of the ApoE epsilon 4 allele who are at a higher risk of developing AD than are cognitively normal elderly individuals.

  5. Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Neurology 2003-05-01 Cognitive tests and assessment

    Previous studies reported substantial contributions of neurofibrillary tangles (NFT), amyloid deposits, and neuronal loss to the development of dementia.

  6. Mild cognitive impairment: Can FDG-PET predict who is to rapidly convert to Alzheimer's disease?

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Neurology 2003-04-22 Mild cognitive impairment

    Patients with mild cognitive impairment (MCI) were assessed, and a metabolic profile associated with conversion to AD at 18-month follow-up was sought.

  7. White matter structural integrity in healthy aging adults and patients with Alzheimer disease: a magnetic resonance imaging study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Archives of neurology 2003-03-01 Brain tissue and pathology

    Imaging and postmortem studies suggest that frontal lobe white matter (FLWM) volume expands until about the age of 44.6 years and then declines.

  8. Early diagnosis of Alzheimer's disease: contribution of structural neuroimaging

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. NeuroImage 2003-02-01 Mild cognitive impairment

    To accurately predict the development of Alzheimer's disease (AD) at its predementia stage would be a major breakthrough from both therapeutic and research standpoints.

  9. Automatic differentiation of anatomical patterns in the human brain: validation with studies of degenerative dementias

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. NeuroImage 2002-09-01 Hippocampus size on brain scans

    We compared voxel-based morphometry (VBM) with independent accurate region-of-interest (ROI) measurements of temporal lobe structures in order to validate the usefulness of this fully automated and unbiased technique in Alzheimer's disease (AD) and semantic dementia (SD).

  10. Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. NeuroImage 2002-09-01 Getting a diagnosis

    A new diagnostic indicator of FDG PET scan abnormality, based on age-adjusted t statistics and an automated voxel-based procedure, is presented and validated in a large data set comprising 110 normal controls and 395 patients with probable Alzheimer's disease (AD) that were studied in eight participating centers.

  11. Visual association test to detect early dementia of the Alzheimer type

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Journal of neurology, neurosurgery, and psychiatry 2002-08-01 Cognitive tests and assessment

    The visual association test (VAT) is a brief learning task based on imagery mnemonics.

  12. Alzheimer's neurofibrillary pathology and the spectrum of cognitive function: findings from the Nun Study

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Annals of neurology 2002-05-01 Clinical safety

    The development of interventions designed to delay the onset of dementia highlights the need to determine the neuropathologic characteristics of individuals whose cognitive function ranges from intact to demented, including those with mild cognitive impairments.

  13. Medial temporal lobe atrophy predicts Alzheimer's disease in patients with minor cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of neurology, neurosurgery, and psychiatry 2002-04-01 Hippocampus size on brain scans

    The ability to detect patients at high risk for Alzheimer type dementia among those with minor cognitive impairment increases when data on age and memory function are combined with measures of medial temporal lobe atrophy.

  14. A comparison of (99m)Tc-HMPAO SPET changes in dementia with Lewy bodies and Alzheimer's disease using statistical parametric mapping

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. European journal of nuclear medicine and molecular imaging 2002-03-05 Cognitive tests and assessment

    Differences in regional cerebral blood flow (rCBF) between subjects with Alzheimer's disease (AD), dementia with Lewy bodies (DLB) and healthy volunteers were investigated using statistical parametric mapping (SPM99).

  15. Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Neurology 2002-03-01 Getting a diagnosis

    Individuals with an isolated pathologic diagnosis of AD, hippocampal sclerosis, frontotemporal degeneration, and neurofibrillary tangle--only degeneration usually had substantial hippocampal atrophy, while those with changes of typical aging did not.

  16. Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. NeuroImage 2002 Brain scans and imaging

    This study performed an anatomical parcellation of the MNI spatially normalized single-subject high-resolution T1 volume by delineating main sulci as landmarks to define 45 anatomical volumes of interest (AVOI) in each hemisphere.

  17. Postmortem MRI and histopathology of white matter changes in Alzheimer brains. A quantitative, comparative study

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Dementia and geriatric cognitive disorders 2002-01-01 Brain scans and imaging

    To evaluate whether magnetic resonance imaging (MRI) of white matter changes in Alzheimer's disease either under- or overestimates the findings on neuropathology.

  18. Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. JAMA 2001-11-01 Getting a diagnosis

    Progressive dementia was detected by PET with a sensitivity of 93% (191/206) and a specificity of 76% (59/78).

  19. MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer’s disease

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Neurobiology of Aging 2001-09-01 Brain scans and imaging

  20. Selective preservation and degeneration within the prefrontal cortex in aging and Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Archives of neurology 2001-09-01 Brain tissue and pathology

    The prefrontal cortex (PFC) is a heterogeneous cortical structure that supports higher cognitive functions, including working memory and verbal abilities.

  21. A Voxel-Based Morphometric Study of Ageing in 465 Normal Adult Human Brains

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. NeuroImage 2001-07-01 Brain scans and imaging

  22. Declining brain activity in cognitively normal apolipoprotein E ɛ4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Proceedings of the National Academy of Sciences 2001-03-13 Genetics

    Cross-sectional positron emission tomography (PET) studies find that cognitively normal carriers of the apolipoprotein E (APOE) epsilon4 allele, a common Alzheimer's susceptibility gene, have abnormally low measurements of the cerebral metabolic rate for glucose (CMRgl) in the same regions as patients with Alzheimer's dementia.

  23. Cortical change in Alzheimer's disease detected with a disease-specific population-based brain atlas

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Cerebral cortex (New York, N.Y. : 1991) 2001-01-01 Cognitive tests and assessment

    We report the first detailed population-based maps of cortical gray matter loss in Alzheimer's disease (AD), revealing prominent features of early structural change.

  24. Visual rating and volumetry of the medial temporal lobe on magnetic resonance imaging in dementia: a comparative study

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of neurology, neurosurgery, and psychiatry 2000-11-01 Cognitive tests and assessment

    It has been shown that atrophy of medial temporal lobe structures such as the hippocampus and entorhinal cortex shown on MRI may distinguish patients with Alzheimer's disease from healthy controls.

  25. Regional metabolic patterns in mild cognitive impairment and Alzheimer's disease: A 1H MRS study

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Neurology 2000-07-01 Mild cognitive impairment

    These findings suggest that the initial 1H MRS change in the pathologic progression of AD is an increase in MI/Cr.

  26. From healthy aging to early Alzheimer's disease: in vivo detection of entorhinal cortex atrophy

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Annals of the New York Academy of Sciences 2000-06-01 Hippocampus size on brain scans

    Using quantitative structural MRI protocols, we examined the effects of age on alterations in entorhinal cortex (EC) volume.

  27. Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Annals of neurology 2000-04-01 Getting a diagnosis

    We used magnetic resonance imaging (MRI) measurements to determine whether persons in the prodromal phase of Alzheimer's disease (AD) could be accurately identified before they developed clinically diagnosed dementia.

  28. The relationship between fMRI activation and cerebral atrophy: comparison of normal aging and alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. NeuroImage 2000-03-01 Brain scans and imaging

    Functional MRI has recently been used to examine activation associated with aging and dementia, yet little is known regarding the effect of cerebral atrophy on fMRI signal.

  29. Using serial registered brain magnetic resonance imaging to measure disease progression in Alzheimer disease: power calculations and estimates of sample size to detect treatment effects

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Archives of neurology 2000-03-01 Brain scans and imaging

    Registration of serial MRI volume images provides a powerful method of quantification of brain atrophy that can be used to monitor progression of AD in clinical trials.

  30. A voxel-based morphometry study of semantic dementia: relationship between temporal lobe atrophy and semantic memory

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Annals of neurology 2000-01-01 Lewy body dementia

    The cortical anatomy of 6 patients with semantic dementia (the temporal lobe variant of frontotemporal dementia) was contrasted with that of a group of age-matched normal subjects by using voxel-based morphometry, a technique that identifies changes in gray matter volume on a voxel-by-voxel basis.

  31. Early diagnosis of Alzheimer disease with positron emission tomography

    ✓ Peer-reviewed alzhub usefulness score 35 out of 100. Alzheimer disease and associated disorders 2000-01-01 Down syndrome and Alzheimer's

    The emergence of drugs that may slow progression of Alzheimer disease, if administered early during its course, has necessitated early diagnosis of the disease itself.

  32. White matter lesions on magnetic resonance imaging in dementia with Lewy bodies, Alzheimer's disease, vascular dementia, and normal aging

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Journal of neurology, neurosurgery, and psychiatry 1999-07-01 Getting a diagnosis

    In common with Alzheimer's disease and vascular dementia, PVHs and WMHs were significantly more extensive in dementia with Lewy bodies than in controls.

  33. Rate of medial temporal lobe atrophy in typical aging and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Neurology 1998-10-01 Hippocampus size on brain scans

    A statistically significant yearly decline in hippocampal volume and an increase in temporal horn volume was identified in elderly control subjects who represent typical aging individuals.

  34. Serotonin in aging, late-life depression, and Alzheimer's disease: the emerging role of functional imaging

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1998-06-01 Brain tissue and pathology

    Serotonin (5-HT) neuron and neurotransmitter loss in normal aging and neuropsychiatric diseases of late life may contribute to behavioral changes commonly observed in the elderly population.

  35. A nonparametric method for automatic correction of intensity nonuniformity in MRI data

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. IEEE Transactions on Medical Imaging 1998 Brain scans and imaging

    A novel approach to correcting for intensity nonuniformity in magnetic resonance (MR) data is described that achieves high performance without requiring a model of the tissue classes present.

  36. Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Neurology 1997-09-01 Getting a diagnosis

    Magnetic resonance imaging (MRI)-based volumetric measurements of medial temporal lobe (MTL) structures can discriminate between normal elderly control subjects and patients with Alzheimer's disease (AD) of moderate to advanced severity.

  37. Medial temporal structures relate to memory impairment in Alzheimer's disease: an MRI volumetric study

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of neurology, neurosurgery, and psychiatry 1997-08-01 Brain scans and imaging

    The presence of perihippocampal damage involving the amygdala proper, its surrounding cortex, and the subiculum further increased the severity of memory impairment attributable to hippocampal damage in Alzheimer's disease.

  38. Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Annals of neurology 1997-07-01 Getting a diagnosis

    This study investigated cerebral glucose metabolism in very early Alzheimer's disease, before a clinical diagnosis of probable Alzheimer's disease is possible, using [18F]fluorodeoxyglucose positron emission tomography.

  39. Localization of manganese superoxide dismutase in the cerebral cortex and hippocampus of Alzheimer-type senile dementia

    ✓ Peer-reviewed alzhub usefulness score 27 out of 100. Osaka city medical journal 1997-06-01 Biomarkers

    Manganese-superoxide dismutase (Mn-SOD) was localized in the cerebral cortex and hippocampus of patients with Alzheimer-type senile dementia (ATD) by immunocytochemistry and the relationship of Mn-SOD with two major pathological features of ATD, i.e., senile plaques and neurofibrillar tangles (NFTs), was examined.

  40. Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Annals of neurology 1997-01-01 Caregiving

    To assess the relationship between dementia, neuronal loss, and neuropathological findings in Alzheimer's disease (AD), we counted the number of neurons, senile plaques, and neurofibrillary tangles in a high-order association cortex.

  41. Quantitative magnetic resonance imaging in geriatric depression and primary degenerative dementia

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. Journal of affective disorders 1997-01-01 Brain scans and imaging

    Quantitative magnetic resonance imaging (MRI) was used to investigate volumes of different brain structures in 19 patients with late-onset major depression (DSM-III-R), 27 patients with Alzheimer's disease (NINCDS-ADRDA criteria) and 13 age matched controls. 3-D MRI sequences were acquired using a Siemens 1.5 T scanner.

  42. Atrophy of the corpus callosum in Alzheimer's disease versus healthy aging

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of the American Geriatrics Society 1996-07-01 Brain scans and imaging

    Atrophy of the CC differentiates HE and ID from AD subjects and tracks the cognitive decline of this disease.

  43. Quantitative assessment of synaptic density in the outer molecular layer of the hippocampal dentate gyrus in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 34 out of 100. Dementia (Basel, Switzerland) 1996-07-01 Brain scans and imaging

    We quantified the synaptic density in the outer molecular layer of the hippocampal dentate gyrus.

  44. Identification of famous faces and famous names in early Alzheimer's disease. Relationship to anterograde episodic and general semantic memory

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Brain : a journal of neurology 1996-02-01 Cognitive tests and assessment

    We assessed remote memory in 33 patients with dementia of Alzheimer's type (DAT) with Mini-Mental State Examination (MMSE) scores between 17 and 30, and 30 matched controls using a Famous Faces Test and Famous Names Test designed to assess face recognition, identification and naming, and name recognition and identification, respectively, together with a range of anterograde episodic and semantic memory tests.

  45. Image analysis of beta-amyloid load in Alzheimer's disease and relation to dementia severity

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Lancet (London, England) 1995-12-01 Cognitive tests and assessment

    The protein beta-amyloid is said to be central to the disease process of Alzheimer's disease (AD).

  46. A diagnostic approach in Alzheimer's disease using three-dimensional stereotactic surface projections of fluorine-18-FDG PET

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995-07-01 Vascular contributions

    3D-SSP enables quantitative data extraction and reliable localization of metabolic abnormalities by means of stereotactic coordinates.

  47. Memory disorders in probable Alzheimer's disease: the role of hippocampal atrophy as shown with MRI

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Journal of neurology, neurosurgery, and psychiatry 1995-05-01 Cognitive tests and assessment

    Magnetic resonance based volumetric measures of hippocampal formation, amygdala (A), caudate nucleus (CN), normalised for total intracranial volume (TIV), were analysed in relation to measures of cognitive deterioration and specific features of memory functions in 18 patients with probable Alzheimer's disease.

  48. Extrapyramidal signs and psychiatric symptoms predict faster cognitive decline in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Archives of neurology 1994-07-01 Cognitive tests and assessment

    A cohort of patients was followed up longitudinally and the likelihood of arriving at two cognitive end points was assessed using the Cox proportional hazards model and eight explanatory variables.

  49. In vivo evaluation of brain iron in Alzheimer's disease and normal subjects using MRI

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Biological psychiatry 1994-04-01 Brain scans and imaging

    Magnetic resonance imaging (MRI) can measure transverse relaxation rate (R2) of tissues.

  50. Volumetric magnetic resonance imaging in men with dementia of the Alzheimer type: correlations with disease severity

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Biological psychiatry 1993-11-01 Brain scans and imaging

    Using magnetic resonance imaging (MRI), we measured the volumes of various brain structures and cerebrospinal fluid (CSF) in 19 men with dementia of the Alzheimer type (DAT) and 18 healthy age-matched control men.

From across this tag

10 of the 1,157 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

All topic tags with their study counts