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Home › Research › Topics › intestinal

intestinal

273 studies tagged intestinal, dated 1995-01-01 to 2026-10-23. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Evidence that the perinatal maternal microbiome mediates metabolite signaling programs that drive sex-specific microglial metabolic alterations and Alzheimer’s disease susceptibility 2026-10-23
  2. Change in gut microbiome precedes symptomatic Alzheimer’s disease and is correlated with amyloid-beta accumulation in the brain 2026-10-19
  3. The Gut–Liver–Brain Axis in Neurodegeneration: Unraveling Metabolic–Immune Crosstalk from Peripheral Sensing to Central Vulnerability 2026-10-08

Studies

273 studies carry this tag.

Date range

1995 to 2026

Top journals

  • Journal of Alzheimer's disease : JAD 13
  • Scientific reports 8
  • Nutrients 7
  • Brain, behavior, and immunity 6
  • Frontiers in cellular and infection microbiology 6

168 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Microbiota-Gut-Brain Axis Dysregulation in Alzheimer's Disease: Multi-Pathway Effects and Therapeutic Potential

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Aging and disease 2024-05-07 Disease mechanisms

    An essential regulator of neurodegenerative conditions like Alzheimer's disease (AD) is the gut microbiota.

  2. Gut microbiota and its metabolites in Alzheimer's disease: from pathogenesis to treatment

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. PeerJ 2024-03-13 Disease mechanisms

    Regulating the gut flora ecological balance upregulates neurotrophic factor expression, regulates the microbiota-gut-brain (MGB) axis, and suppresses the inflammatory responses.

  3. The contribution of age-related changes in the gut-brain axis to neurological disorders

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Gut microbes 2024-01-18 Disease mechanisms

    Trillions of microbes live symbiotically in the host, specifically in mucosal tissues such as the gut.

  4. Current understanding of the Alzheimer's disease-associated microbiome and therapeutic strategies

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Experimental & molecular medicine 2024-01-04 Disease mechanisms

    Alzheimer's disease (AD) is a fatal progressive neurodegenerative disease.

  5. Gut microbiota, circulating cytokines and dementia: a Mendelian randomization study

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of neuroinflammation 2024-01-04 Genetics

    There were 20 positive and 16 negative causal effects between genetic liability in the gut microbiota and dementia.

  6. Gut Microbiome in Alzheimer's Disease: from Mice to Humans

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Current neuropharmacology 2024 Disease mechanisms

    Alzheimer's disease (AD) is the most prevalent type of dementia, but its etiopathogenesis is not yet fully understood.

  7. Intestinal Barrier Function and Neurodegenerative Disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. CNS & neurological disorders drug targets 2024 Disease mechanisms

    Neurodegenerative diseases are caused by the loss of neurons and/or their myelin sheaths, which deteriorate over time and become dysfunctional.

  8. Magnesium-L-threonate treats Alzheimer's disease by modulating the microbiota-gut-brain axis

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Neural regeneration research 2023-12-21 Disease mechanisms

    JOURNAL/nrgr/04.03/01300535-202410000-00029/figure1/v/2024-02-06T055622Z/r/image-tiff Disturbances in the microbiota-gut-brain axis may contribute to the development of Alzheimer's disease.

  9. Pathways linking microbiota-gut-brain axis with neuroinflammatory mechanisms in Alzheimer's pathophysiology

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Microbiome research reports 2023-12-06 Disease mechanisms

    Disturbances in the local and peripheral immune systems are closely linked to a wide range of diseases.

  10. Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Brain : a journal of neurology 2023-12-01 Disease mechanisms

    Alzheimer's disease is a complex neurodegenerative disorder leading to a decline in cognitive function and mental health.

  11. Chiral nanoparticle-remodeled gut microbiota alleviates neurodegeneration via the gut-brain axis

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Nature aging 2023-11-09 Disease mechanisms

    Alzheimer's disease (AD) is characterized by amyloid-β accumulation in the brain and hyperphosphorylated tau aggregation, as well as neuroinflammation.

  12. Gut microbiome-targeted therapies for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Gut microbes 2023-11-07 Disease mechanisms

    The advent of high-throughput 'omics' technologies has improved our knowledge of gut microbiome in human health and disease, including Alzheimer's disease (AD), a neurodegenerative disorder.

  13. Impact of Microbiome-Brain Communication on Neuroinflammation and Neurodegeneration

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. International journal of molecular sciences 2023-10-05 Disease mechanisms

    The gut microbiome plays a pivotal role in maintaining human health, with numerous studies demonstrating that alterations in microbial compositions can significantly affect the development and progression of various immune-mediated diseases affecting both the digestive tract and the central nervous system (CNS).

  14. The role of Lactobacillus in inflammatory bowel disease: from actualities to prospects

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Cell death discovery 2023-09-29 Disease mechanisms

    Inflammatory Bowel Disease (IBD), a chronic nonspecific intestinal inflammatory disease, is comprised of Ulcerative Colitis (UC) and Crohn's Disease (CD).

  15. Microbiota-gut-brain axis and ketogenic diet: how close are we to tackling epilepsy?

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Microbiome research reports 2023-08-29 Disease mechanisms

    The microbiota-gut-brain axis refers to the intricate bidirectional communication between commensal microorganisms residing in the digestive tract and the central nervous system, along neuroendocrine, metabolic, immune, and inflammatory pathways.

  16. Gastrointestinal Dysfunction in Neurological and Neurodegenerative Disorders

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Seminars in neurology 2023-08-22 Disease mechanisms

    Increasing research links the gut microbiome to neurodegenerative disorders.

  17. The gut microbiota-brain axis in neurological disorder

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Frontiers in neuroscience 2023-08-04 Disease mechanisms

    The gut microbiota (GM) plays an important role in the physiology and pathology of the host.

  18. The gut-brain vascular axis in neuroinflammation

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Seminars in immunology 2023-07-07 Disease mechanisms

    The multifaceted microbiota characterizing our gut plays a crucial role in maintaining immune, metabolic and tissue homeostasis of the intestine as well as of distal organs, including the central nervous system.

  19. Microbiome Alterations and Alzheimer's Disease: Modeling Strategies with Transgenic Mice

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Biomedicines 2023-06-27 Disease mechanisms

    In the last decade, the role of the microbiota-gut-brain axis has been gaining momentum in the context of many neurodegenerative and metabolic disorders, including Alzheimer's disease (AD) and diabetes, respectively.

  20. The intestinal microbiota as an ally in the treatment of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Gut microbiome (Cambridge, England) 2023-06-19 Disease mechanisms

    The evolution of the understanding of the intestinal microbiota and its influence on our organism leverages it as a potential protagonist in therapies aimed at diseases that affect not only the intestine but also neural pathways and the central nervous system itself.

  21. Gut microbiome composition may be an indicator of preclinical Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Science translational medicine 2023-06-14 Disease mechanisms

    Alzheimer's disease (AD) pathology is thought to progress from normal cognition through preclinical disease and ultimately to symptomatic AD with cognitive impairment.

  22. Dysbiosis and Alzheimer's disease: role of probiotics, prebiotics and synbiotics

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Naunyn-Schmiedeberg's archives of pharmacology 2023-06-07 Disease mechanisms

    Alzheimer's disease (AD) is a neurodegenerative disease characterized by dementia and the accumulation of amyloid beta in the brain.

  23. Emerging role of gut microbiota dysbiosis in neuroinflammation and neurodegeneration

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Frontiers in neurology 2023-05-15 Disease mechanisms

    Alzheimer's disease (AD), is a chronic age-related progressive neurodegenerative disorder, characterized by neuroinflammation and extracellular aggregation of Aβ peptide.

  24. Microbiota-gut-brain axis and related therapeutics in Alzheimer's disease: prospects for multitherapy and inflammation control

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Reviews in the neurosciences 2023-04-20 Disease mechanisms

    Alzheimer's disease (AD) is the most common type of dementia in the elderly and causes neurodegeneration, leading to memory loss, behavioral disorder, and psychiatric impairment.

  25. Probiotic intervention benefits multiple neural behaviors in older adults with mild cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Geriatric nursing (New York, N.Y.) 2023-03-28 Disease mechanisms

    Probiotic supplements were shown to improve cognitive function in Alzheimer's disease (AD) patients.

  26. The gut microbiome modulates the transformation of microglial subtypes

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Molecular psychiatry 2023-03-13 Disease mechanisms

    Clinical and animal studies have shown that gut microbiome disturbances can affect neural function and behaviors via the microbiota-gut-brain axis, and may be implicated in the pathogenesis of several brain diseases.

  27. Gut Microbiota, an Additional Hallmark of Human Aging and Neurodegeneration

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Neuroscience 2023-03-08 Disease mechanisms

    Gut microbiota represents a diverse and dynamic population of microorganisms harbouring the gastrointestinal tract, which influences host health and disease.

  28. The Crosstalk between Microbiome and Mitochondrial Homeostasis in Neurodegeneration

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Cells 2023-01-28 Disease mechanisms

    Mitochondria are highly dynamic organelles that serve as the primary cellular energy-generating system.

  29. ApoE isoform- and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Science (New York, N.Y.) 2023-01-13 Disease mechanisms

    Tau-mediated neurodegeneration is a hallmark of Alzheimer's disease.

  30. ALZHEIMER'S DISEASE AND ITS RELATIONSHIP WITH THE MICROBIOTA-GUT-BRAIN AXIS

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Arquivos de gastroenterologia 2023 Disease mechanisms

    The composition of the gut microbiota influences the CNS, resulting in changes in host behavior and may be related to the development of neurodegenerative diseases.

  31. Gut-derived β-amyloid: Likely a centerpiece of the gut-brain axis contributing to Alzheimer's pathogenesis

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Gut microbes 2023 Disease mechanisms

    Peripheral β-amyloid (Aβ), including those contained in the gut, may contribute to the formation of Aβ plaques in the brain, and gut microbiota appears to exert an impact on Alzheimer's disease (AD) via the gut-brain axis, although detailed mechanisms are not clearly defined.

  32. Gut microbiota-derived metabolites and their importance in neurological disorders

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Molecular biology reports 2022-11-18 Disease mechanisms

    Microbial-derived metabolites are the intermediate or end products of bacterial digestion.

  33. Microbiome-gut-brain dysfunction in prodromal and symptomatic Lewy body diseases

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of neurology 2022-11-10 Disease mechanisms

    Lewy body diseases, such as Parkinson's disease and dementia with Lewy bodies, vary in their clinical phenotype but exhibit the same defining pathological feature, α-synuclein aggregation.

  34. The intestinal barrier in disorders of the central nervous system

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. The lancet. Gastroenterology & hepatology 2022-11-02 Disease mechanisms

    The intestinal barrier, which primarily consists of a mucus layer, an epithelial barrier, and a gut vascular barrier, has a crucial role in health and disease by facilitating nutrient absorption and preventing the entry of pathogens.

  35. Microbiome in Anxiety and Other Psychiatric Disorders

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. The Medical clinics of North America 2022-10-28 Disease mechanisms

    Initial studies suggested that the fluctuations in the quantity, variety, and composition of the gut microbiota can significantly affect disease processes.

  36. Gut microbiome and human health: Exploring how the probiotic genus Lactobacillus modulate immune responses

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Frontiers in pharmacology 2022-10-24 Disease mechanisms

    The highest density of microbes resides in human gastrointestinal tract, known as "Gut microbiome".

  37. The emerging role of the microbiome in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. International review of neurobiology 2022-10-13 Disease mechanisms

    Alzheimer's disease (AD) is the most prevalent form of dementia and can be influenced by genetic and environmental factors.

  38. Enteric nervous system and intestinal epithelial regulation of the gut-brain axis

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. The Journal of allergy and clinical immunology 2022-09 Disease mechanisms

    The gut-brain axis describes a bidirectional interplay within the enteric environment between the intestinal epithelium, the mucosal immune system, and the microbiota with the enteric nervous system.

  39. Diet, Gut Microbiome, and Cognitive Decline

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Current nutrition reports 2022-08-26 Disease mechanisms

    An epidemic of age-associated cognitive decline, most commonly ascribed to neurodegenerative conditions such as Alzheimer's and Parkinson's disease, is causing healthcare costs to soar and devastating caregivers.

  40. Faecal microbiota transplant ameliorates gut dysbiosis and cognitive deficits in Huntington's disease mice

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Brain communications 2022-08-12 Disease mechanisms

    Huntington's disease is a neurodegenerative disorder involving psychiatric, cognitive and motor symptoms.

  41. Microbiota-derived metabolite Indoles induced aryl hydrocarbon receptor activation and inhibited neuroinflammation in APP/PS1 mice

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Brain, behavior, and immunity 2022-08-10 Disease mechanisms

    Gut microbiota alterations might affect the development of Alzheimer's disease (AD) through microbiota-derived metabolites.

  42. Mechanisms of Short-Chain Fatty Acids Derived from Gut Microbiota in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Aging and disease 2022-07-11 Disease mechanisms

    Short-chain fatty acids (SCFAs) are important metabolites derived from the gut microbiota through fermentation of dietary fiber.

  43. The Role of Microbiome in Brain Development and Neurodegenerative Diseases

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Molecules (Basel, Switzerland) 2022-05-25 Disease mechanisms

    Hundreds of billions of commensal microorganisms live in and on our bodies, most of which colonize the gut shortly after birth and stay there for the rest of our lives.

  44. Microbiota-gut-brain axis in the Alzheimer's disease pathology - an overview

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Neuroscience research 2022-05-14 Disease mechanisms

    Alzheimer's disease (AD) and related dementias (ADRD) are still a serious global public health concern more than a century after the German neuropathologist and psychiatrist Dr. Aloysius Alzheimer described the first case.

  45. Gut Microbiota Modification via Glucagon-like Peptide-1 with Beneficial Neuroprotective Effects

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Middle East journal of digestive diseases 2022-04-30 Drug development

    The results showed that intestinal expression of GLP-1 1 could reduce the intestinal pathogenic genus such as Enterobacteriaceae and was obviously associated with a greater number of beneficial genera such as Lactobacillus and Akkermansia.

  46. Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Microbiome 2022-04-29 Brain scans and imaging

    These findings demonstrate that the aging gut microbiota drives detrimental changes in the gut-brain and gut-retina axes suggesting that microbial modulation may be of therapeutic benefit in preventing inflammation-related tissue decline in later life.

  47. Linking circadian rhythms to microbiome-gut-brain axis in aging-associated neurodegenerative diseases

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Ageing research reviews 2022-04-08 Disease mechanisms

    Emerging evidence suggests that both disruption of circadian rhythms and gut dysbiosis are closely related to aging-associated neurodegenerative diseases.

  48. Gut Microbiota Interact With the Brain Through Systemic Chronic Inflammation: Implications on Neuroinflammation, Neurodegeneration, and Aging

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Frontiers in immunology 2022-04-07 Disease mechanisms

    It has been noticed in recent years that the unfavorable effects of the gut microbiota could exhaust host vigor and life, yet knowledge and theory are just beginning to be established.

  49. Guts Imbalance Imbalances the Brain: A Review of Gut Microbiota Association With Neurological and Psychiatric Disorders

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Frontiers in medicine 2022-03-31 Disease mechanisms

    Over the last 10 years, there has been a growing interest in the relationship between gut microbiota, the brain, and neurologic-associated affections.

  50. Metabolites of soil microorganisms modulate amyloid β production in Alzheimer's neurons

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Scientific reports 2022-03-02 Biomarkers

    Microbial flora is investigated to be related with neuropathological conditions in Alzheimer's disease (AD), and is attracting attention as a drug discovery resource.

From across this tag

8 of the 273 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 8. The same 8 appear here every time.

All topic tags with their study counts