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273 studies tagged intestinal, dated 1995-01-01 to 2026-10-23. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Evidence that the perinatal maternal microbiome mediates metabolite signaling programs that drive sex-specific microglial metabolic alterations and Alzheimer’s disease susceptibility 2026-10-23
- Change in gut microbiome precedes symptomatic Alzheimer’s disease and is correlated with amyloid-beta accumulation in the brain 2026-10-19
- The Gut–Liver–Brain Axis in Neurodegeneration: Unraveling Metabolic–Immune Crosstalk from Peripheral Sensing to Central Vulnerability 2026-10-08
Studies
273 studies carry this tag.
Date range
1995 to 2026
Top journals
- Journal of Alzheimer's disease : JAD 13
- Scientific reports 8
- Nutrients 7
- Brain, behavior, and immunity 6
- Frontiers in cellular and infection microbiology 6
168 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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The gut microbiota has been linked to various neurological disorders via the gut-brain axis.
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Gut dysbiosis, a primary factor behind various gastrointestinal disorders may also augment lipopolysaccharides, pro-inflammatory cytokines, T helper cells and monocytes causing increased intestinal and BBB permeability via microbiota-gut-brain axis.
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Some observational studies have instead demonstrated that, in older individuals, frailty and Alzheimer-type dementia are associated with fecal microbiota dysbiosis, that is, reduced biodiversity and overexpression of pathobionts.
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50/100
These findings provide additional insight into gut microbial involvement in AD and add to the growing understanding of the gut-brain axis.
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Overall, we found that probiotic and selenium co-supplementation for 12 weeks to patients with AD improved cognitive function and some metabolic profiles.
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The gut-brain axis is increasingly recognized as an important pathway of communication and of physiological regulation, and gut microbiota seems to play a significant role in this mutual relationship.
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It has been suggested that exercise training and probiotic supplementation could decelerate the progress of functional and biochemical deterioration in APP/PS1 transgenic mice (APP/PS1 TG ).
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The bidirectional communication between the central nervous system (CNS) and the gut microbiota plays a pivotal role in human health.
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We report for the first time an association between altered BA profile, genetic variants implicated in AD, and cognitive changes in disease using a large multicenter study.
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This is the first study to show serum-based BA metabolites are associated with "A/T/N" AD biomarkers, providing further support for a role of BA pathways in AD pathophysiology.
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Alzheimer's disease (AD) is an increasingly common neurodegenerative disease.
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Cognitive frailty, defined as the coexistence of mild cognitive impairment symptoms and physical frailty phenotype in older persons, is increasingly considered the main geriatric condition predisposing to dementia.
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Alzheimer's disease (AD) is associated with cognitive dysfunction.
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38/100
The number of bacterial cells living within the human body is approximately equal to, or greater than, the total number of human cells.
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One of the most important scientific discoveries of recent years was the disclosure that the intestinal microflora takes part in bidirectional communication between the gut and the brain.
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Alzheimer's disease is characterized by cognitive dysfunction and aging is an important predisposing factor; however, the pathological and therapeutic mechanisms are not fully understood.
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55/100
In recent years evidence has emerged that neurodegenerative diseases (NDs) are strongly associated with the microbiome composition in the gut.
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Neurological diseases, such as Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis (ALS) and multiple sclerosis, are often associated with functional gastrointestinal disorders.
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41/100
Neurovascular integrity, including cerebral blood flow (CBF) and blood-brain barrier (BBB) function, plays a major role in determining cognitive capability.
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39/100
Frailty, which is a syndrome that encompasses losses in physical, psychological and social domains, is responsible for enhanced vulnerability to endogenous and/or exogenous stressors.
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Alzheimer's disease (AD) is a progressive neurodegenerative disease that develops insidiously and causes dementia finally.
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The gut-brain axis is a bidirectional communication network functionally linking the gut and the central nervous system (CNS).
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The gastrointestinal microbiota affects brain function, including memory and learning.
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Parkinson's disease (PD) is a debilitating neurodegenerative condition associated with tremor, rigidity, dementia, and gastrointestinal symptoms such as constipation, nausea and vomiting.
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The human gut is a composite anaerobic environment with a large, diverse and dynamic enteric microbiota, represented by more than 100 trillion microorganisms, including at least 1000 distinct species.
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Previous studies suggest that gut microbiota is associated with neuropsychiatric disorders, such as Parkinson's disease, amyotrophic lateral sclerosis, and depression.
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Though seemingly distinct and autonomous, emerging evidence suggests there is a bidirectional interaction between the intestinal microbiota and the brain.
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Recent studies have suggested the role of an infectious component in the pathogenesis of Alzheimer's disease (AD).
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Gut microbiota influences the central nervous system disorders such as Alzheimer's disease (AD).
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Our studies support the hypothesis that intestinal microbiota may help protect against AD, in part, by supporting the generation of select SCFAs, which interfere with the formation of toxic soluble Aβ aggregates.
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It has previously been shown that the consumption of probiotics may have beneficial effects not only on peripheral tissues but also on the central nervous system and behavior via the microbiota-gut-brain axis, raising the possibility that treatment with probiotics could be an effective therapeutic strategy for managing neurodegenerative disorders.
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The purposes of this review were as follows: first, to provide an overview of the gut microbiota and its interactions with the gut and the central nervous system (the microbiota-gut-brain axis) in health, second, to review the relevance of this axis to the pathogenesis of neurodegenerative diseases, such as Parkinson's disease, and, finally, to assess the potential for microbiota-targeted therapies.
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The gut microbiota (GM) is a complex, evolutionarily molded ecological system, which contributes to a variety of physiological functions.
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-oxide (TMAO) is a small organic molecule, derived from the intestinal and hepatic metabolism of dietary choline and carnitine.
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Recent evidence suggests the commensal microbiome regulates host immunity and influences brain function; findings that have ramifications for neurodegenerative diseases.
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Abundant clinical, epidemiological, imaging, genetic, molecular and pathophysiological data together indicate that there occur an unusual inflammatory reaction and a disruption of the innate-immune signaling system in Alzheimer’s disease (AD) brain.
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38/100
There is a growing appreciation of the role of the gut microbiota in all aspects of health and disease, including brain health.
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The study revealed that, L. plantarum MTCC1325 might have anti-Alzheimer properties against D-Galactose induced Alzheimer's disease.
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Although the potential contribution of the human gastrointestinal (GI) tract microbiome to human health, aging, and disease is becoming increasingly acknowledged, the molecular mechanics and signaling pathways of just how this is accomplished is not well-understood.
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The gut microbiota is essential to health and has recently become a target for live bacterial cell biotherapies for various chronic diseases including metabolic syndrome, diabetes, obesity and neurodegenerative disease.
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45/100
Neuroinflammation caused by local deposits of Aβ 42 in the brain is key for the pathogenesis and progression of Alzheimer's disease.
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Gut microbiota has a proven role in regulating multiple neuro-chemical pathways through the highly interconnected gut-brain axis.
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The gut and brain form the gut-brain axis through bidirectional nervous, endocrine, and immune communications.
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Almost half the cells and 1% of the unique genes found in our bodies are human, the rest are from microbes, predominantly bacteria, archaea, fungi, and viruses.
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41/100
Alzheimer's disease is the most common form of dementia in the western world, however there is no cure available for this devastating neurodegenerative disorder.
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Gut microbiota (GM) can influence various neurological outcomes, like cognition, learning, and memory.
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The diverse collection of microorganisms that inhabit the gastrointestinal tract, collectively called the gut microbiota, profoundly influences many aspects of host physiology, including nutrient metabolism, resistance to infection and immune system development.
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The regulation of physiological gut functions such as peristalsis or secretion of digestive enzymes by the central nervous system via the Nervus vagus is well known.
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The topic of gut microbiota is currently attracting considerable interest as a potential factor in Alzheimer's disease (AD).
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Alzheimer's disease (AD) is a neurodegenerative brain disease and is the most common form of dementia.
From across this tag
9 of the 273 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.
- Suppression of gut dysbiosis by Bifidobacterium longum alleviates cognitive decline in 5XFAD transgenic and aged mice
- Alzheimer's disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis
- Gut Microbial Metabolism as a Dynamic Interface in Neurodegenerative Diseases
- Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer's disease mouse model
- Neurodegenerative Disorders and the Gut-Microbiome-Brain Axis: A Literature Review
- Chronic neuroinflammation in rats reproduces components of the neurobiology of Alzheimer's disease
- Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer's Disease: A Randomized, Double-Blind and Controlled Trial
- Rapid improvement in Alzheimer's disease symptoms following fecal microbiota transplantation: a case report
- Microbiota-gut-brain axis in neurodegenerative diseases: molecular mechanisms and therapeutic targets