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Newest in this topic

  1. Evidence that the perinatal maternal microbiome mediates metabolite signaling programs that drive sex-specific microglial metabolic alterations and Alzheimer’s disease susceptibility 2026-10-23
  2. Change in gut microbiome precedes symptomatic Alzheimer’s disease and is correlated with amyloid-beta accumulation in the brain 2026-10-19
  3. The Gut–Liver–Brain Axis in Neurodegeneration: Unraveling Metabolic–Immune Crosstalk from Peripheral Sensing to Central Vulnerability 2026-10-08

Studies

273 studies carry this tag.

Date range

1995 to 2026

Top journals

  • Journal of Alzheimer's disease : JAD 13
  • Scientific reports 8
  • Nutrients 7
  • Brain, behavior, and immunity 6
  • Frontiers in cellular and infection microbiology 6

168 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Human gut microbiota: the links with dementia development

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Protein & cell 2016-11-19 Disease mechanisms

    Dementia is a comprehensive category of brain diseases that is great enough to affect a person's daily functioning.

  2. Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer's Disease: A Randomized, Double-Blind and Controlled Trial

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Frontiers in aging neuroscience 2016-11-10 Clinical trials

    Alzheimer's disease (AD) is associated with severe cognitive impairments as well as some metabolic defects.

  3. Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nutrition reviews 2016-10-01 Prevention and risk

    It has been hypothesized that alterations in the composition of the gut microbiota might be associated with the onset of certain human pathologies, such as Alzheimer disease, a neurodegenerative syndrome associated with cerebral accumulation of amyloid-β fibrils.

  4. Bacteroides fragilis Lipopolysaccharide and Inflammatory Signaling in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Frontiers in microbiology 2016-09-26 Disease mechanisms

    The human microbiome consists of ~3.8 × 10 13 symbiotic microorganisms that form a highly complex and dynamic ecosystem: the gastrointestinal (GI) tract constitutes the largest repository of the human microbiome by far, and its impact on human neurological health and disease is becoming increasingly appreciated.

  5. Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Neurobiology of aging 2016-08-31 Inflammation and the immune system

    Amy+ patients showed higher levels of pro-inflammatory cytokines (IL-6, CXCL2, NLRP3, and IL-1β) compared with both controls and with Amy- patients.

  6. From focal sepsis to periodontal medicine: a century of exploring the role of the oral microbiome in systemic disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. The Journal of physiology 2016-08-28 Disease mechanisms

    The oral microbiome is established within a few minutes after birth and consists of stable multi-species communities that engage in a dynamic equilibrium with the host immune system.

  7. Alzheimer's disease and gut microbiota

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Science China. Life sciences 2016-08-26 Disease mechanisms

    Alzheimer's disease (AD) is a most common neurodegenerative disorder, which associates with impaired cognition.

  8. Towards understanding brain-gut-microbiome connections in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. BMC systems biology 2016-08-26 Risk factors

    Employing an integrated computational approach, we provide intriguing and supporting evidence for a role of microbial metabolites, an important modifiable environmental factor, in AD etiology.

  9. The Gut-Brain Axis, BDNF, NMDA and CNS Disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurochemical research 2016-08-23 Disease mechanisms

    Gastro-intestinal (GI) microbiota and the 'gut-brain axis' are proving to be increasingly relevant to early brain development and the emergence of psychiatric disorders.

  10. Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Scientific reports 2016-07-21 Disease mechanisms

    Severe amyloidosis and plaque-localized neuro-inflammation are key pathological features of Alzheimer's disease (AD).

  11. The bowel and beyond: the enteric nervous system in neurological disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nature reviews. Gastroenterology & hepatology 2016-07-20 Disease mechanisms

    The enteric nervous system (ENS) is large, complex and uniquely able to orchestrate gastrointestinal behaviour independently of the central nervous system (CNS).

  12. Irritable Bowel Syndrome Is Associated with an Increased Risk of Dementia: A Nationwide Population-Based Study

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. PloS one 2016-01-05 Digital health tools

    IBS is associated with an increased risk of dementia, and this effect is obvious only in patients who are ≥50 years old.

  13. Gut microbiota in autism and mood disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. World journal of gastroenterology 2016-01-01 Disease mechanisms

    The hypothesis of an important role of gut microbiota in the maintenance of physiological state into the gastrointestinal (GI) system is supported by several studies that have shown a qualitative and quantitative alteration of the intestinal flora in a number of gastrointestinal and extra-gastrointestinal diseases.

  14. Gut microbiome in health and disease: Linking the microbiome-gut-brain axis and environmental factors in the pathogenesis of systemic and neurodegenerative diseases

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Pharmacology & therapeutics 2015-11-26 Disease mechanisms

    The gut microbiome comprises the collective genome of the trillions of microorganisms residing in our gastrointestinal ecosystem.

  15. Neuroprotective Effects of Clostridium butyricum against Vascular Dementia in Mice via Metabolic Butyrate

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. BioMed research international 2015-10-07 Disease mechanisms

    Probiotics actively participate in neuropsychiatric disorders.

  16. Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Molecular nutrition & food research 2015-04-27 Disease mechanisms

    Scope Grape seed polyphenol extract (GSPE) is receiving increasing attention for its potential preventative and therapeutic roles in Alzheimer's disease (AD) and other age-related neurodegenerative disorders.

  17. Mechanisms of molecular mimicry involving the microbiota in neurodegeneration

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Alzheimer's disease : JAD 2015-01-01 Genetics

    The concept of molecular mimicry was established to explain commonalities of structure which developed in response to evolutionary pressures.

  18. The microbiome and disease: reviewing the links between the oral microbiome, aging, and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Alzheimer's disease : JAD 2015-01-01 Disease mechanisms

    This review, gathered from diverse sources, shows how our microbiome influences health and ultimately how well we age.

  19. Serum IgG antibody levels to periodontal microbiota are associated with incident Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. PloS one 2014-12-18 Disease mechanisms

    Serum IgG levels to common periodontal microbiota are associated with risk for developing incident AD.

  20. Maternal immune activation and abnormal brain development across CNS disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nature reviews. Neurology 2014-10-14 Inflammation and the immune system

    Epidemiological studies have shown a clear association between maternal infection and schizophrenia or autism in the progeny.

  21. Twenty years of research on cytokine-induced sickness behavior

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Brain, behavior, and immunity 2006-11-07 Risk factors

    Cytokine-induced sickness behavior was recognized within a few years of the cloning and expression of interferon-alpha, IL-1 and IL-2, which occurred around the time that the first issue of Brain, Behavior, and Immunity was published in 1987.

  22. Chronic neuroinflammation in rats reproduces components of the neurobiology of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Brain research 1998-01-01 Biomarkers

    Inflammatory processes may play a critical role in the pathogenesis of the degenerative changes and cognitive impairments associated with Alzheimer's disease (AD).

  23. Corticotropin-releasing factor receptors: physiology, pharmacology, biochemistry and role in central nervous system and immune disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Psychoneuroendocrinology 1995-01-01 Disease mechanisms

    In addition to a physiological role for CRF in integrating the responses of the brain, endocrine and immune systems to physiological, psychological and immunological stimuli, recent clinical data implicate CRF in the etiology and pathophysiology of various endocrine, psychiatric, neurologic and inflammatory illnesses.

From across this tag

10 of the 273 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

All topic tags with their study counts