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Newest in this topic

  1. Diagnostic accuracy of remote self-administered digital cognitive assessment by clinical diagnosis and Alzheimer's disease PET imaging biomarkers 2026-09-25
  2. Multi-scale 3D CNN with imbalance-aware training for structural MRI-based six-class Alzheimer disease staging 2026-09-22
  3. T1 mapping in Alzheimer’s disease: a quantitative MRI study with amyloid-PET correlation 2026-09-21

Studies

842 studies carry this tag.

Date range

1983 to 2026

Top journals

  • Neurology 83
  • Journal of nuclear medicine : official publication, Society of Nuclear Medicine 42
  • Brain : a journal of neurology 34
  • NeuroImage 31
  • Alzheimer s & Dementia 30

283 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Hypoperfusion in frontotemporal dementia and Alzheimer disease by arterial spin labeling MRI

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Neurology 2006-10-01 Brain scans and imaging

    Frontotemporal dementia and Alzheimer disease display different spatial distributions of hypoperfusion on arterial spin labeling MRI.

  2. Tracking atrophy progression in familial Alzheimer's disease: a serial MRI study

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. The Lancet. Neurology 2006-10-01 Mild cognitive impairment

    Mutation carriers had significantly increased hippocampal and whole-brain atrophy rates compared with controls and these differences increased with time.

  3. [11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Neurology 2006-08-01 Brain scans and imaging

    Longitudinal studies will be required to determine the association of elevated [(11)C]PIB binding and risk of developing dementia of the Alzheimer type.

  4. Magnetoencephalographic evaluation of resting-state functional connectivity in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. NeuroImage 2006-07-11 Brain scans and imaging

    Statistical interdependencies between magnetoencephalographic signals recorded over different brain regions may reflect the functional connectivity of the resting-state networks.

  5. Conversion of mild cognitive impairment to Alzheimer disease predicted by hippocampal atrophy maps

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Archives of neurology 2006-05-01 How common it is

    Smaller hippocampi and specifically CA1 and subicular involvement are associated with increased risk for conversion from MCI to AD.

  6. An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. NeuroImage 2006-03-14 Brain scans and imaging

    In this study, researchers assessed the validity and reliability of an automated labeling system developed to subdivide the human cerebral cortex on magnetic resonance images into gyral based regions of interest.

  7. Diffusion tensor imaging in early Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Psychiatry research 2006-03-07 Brain scans and imaging

    Our aim was to investigate the extent of white matter tissue damage in patients with early Alzheimer disease (AD) using diffusion tensor magnetic resonance imaging (DTI).

  8. Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Annals of neurology 2006-03-01 Getting a diagnosis

    These observations suggest that brain amyloid deposition results in low CSF Abeta(42), and that amyloid imaging and CSF Abeta(42) may potentially serve as antecedent biomarkers of (preclinical) AD.

  9. Magnetic resonance imaging of iron deposition in neurological disorders

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Topics in magnetic resonance imaging : TMRI 2006-02-01 Brain scans and imaging

    Deposition of iron in the brain is proposed to play a role in the pathophysiology of the normal aging process and neurodegenerative diseases.

  10. Differential regional atrophy of the cingulate gyrus in Alzheimer disease: a volumetric MRI study

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Cerebral cortex (New York, N.Y. : 1991) 2006-01-04 Brain scans and imaging

    Magnetic resonance imaging-based volumetric measurements provide a useful technique for quantifying in vivo regional cerebral atrophy in Alzheimer disease (AD).

  11. Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: a comparative analysis.

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005-12-01 Brain scans and imaging

    Of the simplified methods for PIB analysis examined, CAR90 provided DVR measures that were most comparable to ART90; CER90 was the most reproducible and SUVR90 produced the largest effect size.

  12. Diffusion magnetic resonance histograms as a surrogate marker and predictor of disease progression in CADASIL: a two-year follow-up study

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Stroke 2005-11-03 Brain scans and imaging

    DTI histograms may be used as an adjunct outcome measure in future therapeutic trials.

  13. Using voxel-based morphometry to map the structural changes associated with rapid conversion in MCI: a longitudinal MRI study

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. NeuroImage 2005-10-01 Mild cognitive impairment

    Capturing the dynamics of gray matter (GM) atrophy in relation to the conversion from mild cognitive impairment (MCI) to clinically probable Alzheimer's disease (AD) would be of considerable interest.

  14. Visual assessment of atrophy on magnetic resonance imaging in the diagnosis of pathologically confirmed young-onset dementias

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Archives of neurology 2005-09-01 Brain scans and imaging

    Despite variation and overlap of atrophy patterns, visual inspection of regional atrophy on MRI may aid in discriminating AD and FTLD.

  15. Measuring atrophy in Alzheimer disease: a serial MRI study over 6 and 12 months

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Neurology 2005-07-01 Brain scans and imaging

    This potential benefit must be balanced against the possibility that ventricular volumes may be more likely to be affected by factors other than neurodegeneration.

  16. Kinetic Modeling of Amyloid Binding in Humans using PET Imaging and Pittsburgh Compound-B

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Journal of Cerebral Blood Flow & Metabolism 2005-06-09 Brain scans and imaging

    A valid quantitative imaging method for the measurement of amyloid deposition in humans could improve Alzheimer's disease (AD) diagnosis and antiamyloid therapy assessment.

  17. MRI predictors of risk of incident Alzheimer disease: a longitudinal study

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Neurology 2005-05-01 Brain scans and imaging

    In nondemented individuals, entorhinal cortex atrophy is associated with risk of Alzheimer disease.

  18. Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. FDG-PET studies in MCI and AD

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. European journal of nuclear medicine and molecular imaging 2005-04-01 Getting a diagnosis

    The demographics of aging suggest a great need for the early diagnosis of dementia and the development of preventive strategies.

  19. 19F and 1H MRI detection of amyloid beta plaques in vivo

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Nature neuroscience 2005-03-13 Brain scans and imaging

    Formation of senile plaques composed of amyloid beta peptide, a pathological hallmark of Alzheimer disease, in human brains precedes disease onset by many years.

  20. EEG coherence reflects regional corpus callosum area in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Journal of neurology, neurosurgery, and psychiatry 2005-01-01 Brain scans and imaging

    Region specific correlations between corpus callosum size and EEG coherence suggest that the decline in interhemispheric connectivity in Alzheimer's disease results from a specific loss of cortical association neurones projecting through the corpus callosum.

  21. Atrophy rate in medial temporal lobe during progression of Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Neurology 2004-12-01 Brain scans and imaging

    Increased annual atrophy rate in the medial temporal lobe is a potential diagnostic marker of the progression of Alzheimer disease.

  22. Disturbed fluctuations of resting state EEG synchronization in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2004-10-28 Brain scans and imaging

    Alzheimer's disease is characterized both by a lower mean level of functional connectivity as well as by diminished fluctuations in the level of synchronization.

  23. MRI and CSF studies in the early diagnosis of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Journal of internal medicine 2004-09-01 Mild cognitive impairment

    In cross-section and longitudinally, our results show that evaluations of the P-tau231 level are highly correlated with reductions in the MRI hippocampal volume and by using CSF and MRI measures together one improves the separation of NL and MCI.

  24. PET imaging of amyloid in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. The Lancet. Neurology 2004-09-01 Getting a diagnosis

    Alzheimer's disease (AD) is the most common form of dementia and is characterised by progressive impairment in cognitive function and behaviour.

  25. Mapping hippocampal and ventricular change in Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. NeuroImage 2004-08-01 Brain scans and imaging

    We developed an anatomical mapping technique to detect hippocampal and ventricular changes in Alzheimer disease (AD).

  26. Mapping distributed sources of cortical rhythms in mild Alzheimer's disease. A multicentric EEG study

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. NeuroImage 2004-05-01 Cognitive tests and assessment

    The study aimed at mapping (i) the distributed electroencephalographic (EEG) sources specific for mild Alzheimer's disease (AD) compared to vascular dementia (VaD) or normal elderly people (Nold) and (ii) the distributed EEG sources sensitive to the mild AD at different stages of severity.

  27. 'In the course of time': a PET study of the cerebral substrates of autobiographical amnesia in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Brain : a journal of neurology 2004-04-21 Disease mechanisms

    Neuroimaging studies in healthy subjects have yielded controversial results about the neural substrates of autobiographical memory.

  28. Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from functional MRI

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Proceedings of the National Academy of Sciences 2004-03-15 Brain scans and imaging

    Recent functional imaging studies have revealed coactivation in a distributed network of cortical regions that characterizes the resting state, or default mode, of the human brain.

  29. Comparison of different MRI brain atrophy rate measures with clinical disease progression in AD

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Neurology 2004-02-01 Brain scans and imaging

    These data support the use of rates of change from serial MRI studies in addition to standard clinical/psychometric measures as surrogate markers of disease progression in AD.

  30. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐B

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. Annals of Neurology 2004-01-21 Brain scans and imaging

    This report describes the first human study of a novel amyloid-imaging positron emission tomography (PET) tracer, termed Pittsburgh Compound-B (PIB), in 16 patients with diagnosed mild AD and 9 controls.

  31. Imaging cerebral atrophy: normal ageing to Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Lancet (London, England) 2004-01-01 How common it is

    Alzheimer's disease is associated with progressive cerebral atrophy, which can be seen on MRI with high resolution.

  32. The Abbey pain scale: a 1-minute numerical indicator for people with end-stage dementia

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. International journal of palliative nursing 2004-01-01 Brain tissue and pathology

    The need for a specialized clinical regimen for patients with dementia who require palliative care has only recently been recognized.

  33. Rey verbal learning test is a useful tool for differential diagnosis in the preclinical phase of Alzheimer's disease: comparison with mild cognitive impairment and normal aging

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. International journal of geriatric psychiatry 2003-11-01 Cognitive tests and assessment

    RAVLT was administered as part of a more extensive neuropsychological battery at baseline evaluation in 116 unselected patients referred by subjective memory complaints (SMC).

  34. Change in rates of cerebral atrophy over time in early-onset Alzheimer's disease: longitudinal MRI study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Lancet (London, England) 2003-10-01 Cognitive tests and assessment

    The extent to which cerebral atrophy in Alzheimer's disease changes with time is unknown.

  35. Changes in premorbid brain volume predict Alzheimer's disease pathology

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Neurology 2003-08-01 Brain scans and imaging

    MRI volumes measured over time are valid biomarkers of pathologic progression of AD across a range of antemortem clinical states.

  36. Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. European journal of nuclear medicine and molecular imaging 2003-05-23 Mild cognitive impairment

    A high percentage of patients with mild cognitive impairment (MCI) develop clinical dementia of the Alzheimer type (AD) within 1 year.

  37. Neuroimaging in Alzheimer disease: an evidence-based review

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Neuroimaging clinics of North America 2003-05-01 Genetics

    Neuroimaging is valuable in predicting future development of AD in patients with MCI and in carriers of the ApoE epsilon 4 allele who are at a higher risk of developing AD than are cognitively normal elderly individuals.

  38. Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Neurology 2003-05-01 Cognitive tests and assessment

    Previous studies reported substantial contributions of neurofibrillary tangles (NFT), amyloid deposits, and neuronal loss to the development of dementia.

  39. Mild cognitive impairment: Can FDG-PET predict who is to rapidly convert to Alzheimer's disease?

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Neurology 2003-04-22 Mild cognitive impairment

    Patients with mild cognitive impairment (MCI) were assessed, and a metabolic profile associated with conversion to AD at 18-month follow-up was sought.

  40. White matter structural integrity in healthy aging adults and patients with Alzheimer disease: a magnetic resonance imaging study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Archives of neurology 2003-03-01 Brain tissue and pathology

    Imaging and postmortem studies suggest that frontal lobe white matter (FLWM) volume expands until about the age of 44.6 years and then declines.

  41. Early diagnosis of Alzheimer's disease: contribution of structural neuroimaging

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. NeuroImage 2003-02-01 Mild cognitive impairment

    To accurately predict the development of Alzheimer's disease (AD) at its predementia stage would be a major breakthrough from both therapeutic and research standpoints.

  42. Automatic differentiation of anatomical patterns in the human brain: validation with studies of degenerative dementias

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. NeuroImage 2002-09-01 Hippocampus size on brain scans

    We compared voxel-based morphometry (VBM) with independent accurate region-of-interest (ROI) measurements of temporal lobe structures in order to validate the usefulness of this fully automated and unbiased technique in Alzheimer's disease (AD) and semantic dementia (SD).

  43. Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. NeuroImage 2002-09-01 Getting a diagnosis

    A new diagnostic indicator of FDG PET scan abnormality, based on age-adjusted t statistics and an automated voxel-based procedure, is presented and validated in a large data set comprising 110 normal controls and 395 patients with probable Alzheimer's disease (AD) that were studied in eight participating centers.

  44. Visual association test to detect early dementia of the Alzheimer type

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Journal of neurology, neurosurgery, and psychiatry 2002-08-01 Cognitive tests and assessment

    The visual association test (VAT) is a brief learning task based on imagery mnemonics.

  45. Alzheimer's neurofibrillary pathology and the spectrum of cognitive function: findings from the Nun Study

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Annals of neurology 2002-05-01 Clinical safety

    The development of interventions designed to delay the onset of dementia highlights the need to determine the neuropathologic characteristics of individuals whose cognitive function ranges from intact to demented, including those with mild cognitive impairments.

  46. Medial temporal lobe atrophy predicts Alzheimer's disease in patients with minor cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of neurology, neurosurgery, and psychiatry 2002-04-01 Hippocampus size on brain scans

    The ability to detect patients at high risk for Alzheimer type dementia among those with minor cognitive impairment increases when data on age and memory function are combined with measures of medial temporal lobe atrophy.

  47. A comparison of (99m)Tc-HMPAO SPET changes in dementia with Lewy bodies and Alzheimer's disease using statistical parametric mapping

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. European journal of nuclear medicine and molecular imaging 2002-03-05 Cognitive tests and assessment

    Differences in regional cerebral blood flow (rCBF) between subjects with Alzheimer's disease (AD), dementia with Lewy bodies (DLB) and healthy volunteers were investigated using statistical parametric mapping (SPM99).

  48. Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Neurology 2002-03-01 Getting a diagnosis

    Individuals with an isolated pathologic diagnosis of AD, hippocampal sclerosis, frontotemporal degeneration, and neurofibrillary tangle--only degeneration usually had substantial hippocampal atrophy, while those with changes of typical aging did not.

  49. Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. NeuroImage 2002 Brain scans and imaging

    This study performed an anatomical parcellation of the MNI spatially normalized single-subject high-resolution T1 volume by delineating main sulci as landmarks to define 45 anatomical volumes of interest (AVOI) in each hemisphere.

  50. Postmortem MRI and histopathology of white matter changes in Alzheimer brains. A quantitative, comparative study

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Dementia and geriatric cognitive disorders 2002-01-01 Brain scans and imaging

    To evaluate whether magnetic resonance imaging (MRI) of white matter changes in Alzheimer's disease either under- or overestimates the findings on neuropathology.

From across this tag

10 of the 838 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

All topic tags with their study counts