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exposure
237 studies tagged exposure, dated 1994-07-01 to 2026-10-11. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Carbonaceous Components Underlying Wildfire Smoke PM 2.5 -Associated Alzheimer’s Disease and Related Dementias in Older US Adults 2026-10-11
- Micro- and nanoplastics alter electrophysiological brain patterns and reshape human neurodevelopmental trajectories 2026-09-24
- Neuroexposomics to Prevent Neurodegenerative Disease: Challenges, Next Steps, and Recommendations 2026-08-31
Studies
237 studies carry this tag.
Date range
1994 to 2026
Top journals
- Journal of Alzheimer's disease : JAD 24
- Environmental research 21
- Environment international 8
- Environmental health perspectives 8
- medRxiv 7
130 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Wildfire smoke exposure is increasing across the U.S., but the long-term neurological effects of smoke-specific fine particulate matter (PM 2.5 ) and its carbonaceous components remain uncertain.
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Environmental microplastics and nanoplastics (MNPs) are emerging contaminants that accumulate in human tissues, including the brain, yet their mechanistic impact on the nervous system remains poorly understood.
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16/100
Neuroexposome research investigates associations between physical, chemical, biological, and psychosocial factors and neurological health.
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Of 2,496 records screened, 26 studies met eligibility, comprising >84,000 older adults across 10 countries: United States, South Korea, United Kingdom, France, Spain, Sweden, Netherlands, Taiwan, Germany, and Japan.
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Alzheimer’s disease (AD) is one of the most common neurodegenerative disorders, yet the environmental drivers that accelerate its progression remain poorly defined.
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In this prospective birth cohort study, prenatal exposure to a persistent environmental toxicant was associated with lower plasma Aβ42/40 ratio and worse cognitive performance in midlife, consistent with DDE accelerating the preclinical trajectory of AD-related biological changes decades before symptom onset.
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Among 2 184 847 Danish citizens aged between 65 and 95 years, there were 3024 individuals with DLB (mean [SD] age, 78 [6], 1894 [62.6%] male) and 3808 with PDD (mean [SD] age, 78 [6], 2400 [63.0%] male) who were matched with 30 240 and 38 080 controls, respectively.
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Direct medical and productivity-related costs associated with incident cases were estimated using a cost-of-illness (COI) framework.
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Ambient air pollution has been associated with increased incidence of chronic disease and is estimated to contribute towards 4.2 million early deaths annually.
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Exposure to the highest quintile of PM 2·5 (Rte:1·14, 95% CI:1·06-1·23), NO x (Rte:1·11, 95% CI:1·03-1·20) or NO 2 (Rte:1·08, 95% CI:0·99-1·16), compared to the lowest quintile, was associated with higher dementia risk.
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Higher exposure to PM 2.5 was associated with cerebral arteriolosclerosis and atherosclerosis at death, consistent with the known vascular toxicity of this pollutant.
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No association between cadmium exposure and dementia incidence was observed.
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Air pollution (AirP) exposure is associated with increased Alzheimer’s disease (AD) risk, yet AirP is chemically heterogeneous, complicating identification of shared pathogenic drivers.
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57/100
Green spaces generally showed an inverse association with EOD risk that was almost linear for AD and inverted U-shaped for non-AD.
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Among the air toxics, higher 1,3-butadiene levels we estimated a hazard ratio of 1.12 (95 % CI: 1.00, 1.25) for incident dementia/CIND per IQR increase in 1,3-butadiene exposures.
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Among 5,699 participants (mean age: 70±8 years), we observed total PM2.5 concentrations ranging from 16 to 206 μg/m3.
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Ambient fine particulate matter (PM2.5) is a key environmental risk factor closely associated with Alzheimer's disease (AD), although its specific molecular mechanisms remain incompletely elucidated.
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Fine particulate matter (PM2.5), a major component of air pollution, poses significant global health risks.
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68/100
At study entry, the mean (SD) age of the participants was 70 (SD, 8.9) years and 41% were males.
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Over 13 years, 65 336 patients with FCMD were identified, with 2584 developing dementia and 10 664 dying.
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Both environmental exposures and genetics are known to play important roles in shaping human aging.
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71/100
In total, 42 eligible studies were included.
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Alzheimer's disease and related dementias are a leading cause of morbidity in our aging populations.
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The odds ratio (OR) for Alzheimer's disease was 0.996 with a p-value of 0.443 using the inverse variance weighted algorithm, and the OR associated with the outcome variable of delirium was 0.393 with a p-value of 0.343.
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We found a significant correlation of CSF α-syn level with PM2.5 in urban participants.
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In this study, 1 282 032 participants ranging from 19 to 452 735 were included in 30 articles published from 2010 to 2022.
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Air pollution is a critical global issue with extensive implications beyond respiratory health, significantly affecting neurological and psychiatric disorders.
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The aggregation and prion-like propagation of tau are the hallmarks of Alzheimer's disease (AD) and other tauopathies.
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55/100
At baseline, 99 participants (10.1%) had covert brain infarcts and 91 (9.3%) had extensive periventricular white matter hyperintensities (WMHs).
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Polycyclic aromatic hydrocarbons (PAHs), which are widely present in incompletely combusted air particulate matter <2.5 μm (PM2.5), tobacco and other organic materials, can enter the human body through various routes and are a class of environmental pollutants with neurotoxic effects.
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During a 12-year period of follow-up, 4,389 incidents of all-cause dementia were identified.
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We had a follow-up of 71 million person-years.
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Regarding exposures to air pollution, there was convincing (class I) evidence for the association between long-term exposure to solvents and a higher incidence of dementia or cognitive impairment (odds ratio, OR=1.139), and highly suggestive (class II) evidence for the association between long-term exposure to some pollutants and higher risk for cognitive disorders (higher incidence of dementia with high vs. low levels of carbon monoxide, CO: OR=1.587; higher incidence of vascular dementia per 1 μg/m 3 increase of nitrogen oxides, NO x : hazard ratio, HR=1.004).
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Our MR analysis identified a notable association between genetically predicted PM2.5 (PM with a diameter of 2.5 μm or less) exposure and an elevated risk of AD (odds ratio, 2.160; 95% confidence interval, 1.481 to 3.149; p < 0.001).
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43/100
Environmental pollution exposures, including air, soil, water, light, and noise pollution, are critical issues that may implicate adverse mental health outcomes.
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SDI score (aHR = 1.08; 95% CI 0.96, 1.22), joint air pollution (aHR = 1.03, 95% CI 0.92, 1.16) and joint SDI with air pollution (aHR = 1.04, 95% CI 0.89, 1.22) were not associated with dementia risk.
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This paper delves into the increasingly recognized yet complex relationship between air pollution and Neurological Diseases.
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Alzheimer's disease (AD) prevalence has increased in the last century which can be attributed to increased lifespan, but environment is also important.
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Here we show that two different PMs derived from exhausts of cars running on EN590 diesel or compressed natural gas (CNG) alter the function of human microglia-like cells in vitro.
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Respiratory viruses have a significant impact on health, as highlighted by the COVID-19 pandemic.
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The neuropathological hallmarks of Alzheimer's disease (AD), Parkinson's disease (PD), frontotemporal lobar degeneration (FTLD), and amyotrophic lateral sclerosis (ALS) are present in urban children exposed to fine particulate matter (PM2.5), combustion and friction ultrafine PM (UFPM), and industrial nanoparticles (NPs).
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We identified 1,041 incident all-cause dementia cases in 4,283 participants over 37,102 person-years of follow-up.
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During a median 11.7 years follow-up, 5 905 incident cases of all-cause dementia were identified.
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16/100
Living in locations with higher PM2.5 (per interquartile range [IQR]=3.17μg/m3) or NO2 (per IQR=6.63ppb) was associated with greater MTL atrophy (βPM2.5 = -0.29, 95% confidence interval [CI]=[-0.41,-0.18]; βNO2 =-0.12, 95%CI=[-0.23,-0.02]).
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The univariable regression models revealed a higher likelihood of dementia diagnosis in patients with dysphagia (odds ratio = 1.493, 95% confidence interval = 1.000-2.228).
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In this cohort study, higher residential PM2.5 levels, especially from agriculture and wildfires, were associated with higher rates of incident dementia, providing further evidence supporting PM2.5 reduction as a population-based approach to promote healthy cognitive aging.
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Epidemiological evidence demonstrates a link between air pollution exposure and the onset and progression of cognitive impairment and Alzheimer's disease (AD).
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43/100
The aging population worldwide is facing a significant increase in age-related non-communicable diseases, including cardiovascular and brain pathologies.
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Among 27 857 participants (mean [SD] age at baseline, 61 [10] years; 15 747 female participants [56.5%]; 19 249 non-Hispanic White participants [69.1%]), 4105 (14.7%) developed dementia during the follow-up period (mean [SD], 10.2 [5.6] years).
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In the first year of follow-up, increased exposure to all air pollutants was associated with an increase in the use of CMHTs in a dose-response manner.
From across this tag
8 of the 237 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 8. The same 8 appear here every time.
- Megacities air pollution problems: Mexico City Metropolitan Area critical issues on the central nervous system pediatric impact
- Long-Term Air Pollution and Traffic Noise Exposures and Mild Cognitive Impairment in Older Adults: A Cross-Sectional Analysis of the Heinz Nixdorf Recall Study
- The link of organophosphorus pesticides with neurodegenerative and neurodevelopmental diseases based on evidence and mechanisms
- Air Pollution and Dementia: A Systematic Review
- Particulate matter and Alzheimer's disease: an intimate connection
- Ambient air pollution and neurotoxicity on brain structure: Evidence from women's health initiative memory study
- Air pollution and dementia in older adults in the Ginkgo Evaluation of Memory Study
- Alzheimer's disease and environmental exposure to lead: the epidemiologic evidence and potential role of epigenetics