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Newest in this topic

  1. Alcohol use disorder accelerates age-related cognitive decline 2026-09-23
  2. A longitudinal study of age-related traits and cognitive function: The Collaborative Amish Aging and Memory Project (CAAMP) 2026-09-20
  3. Associations of menopause hormone therapy with late-life cognition and brain health vary by formulation and APOEε4 presence 2026-09-20

Studies

1,138 studies carry this tag.

Date range

1986 to 2026

Top journals

  • Alzheimer s & Dementia 42
  • Neurology 41
  • Journal of the American Geriatrics Society 36
  • Journal of Alzheimer's disease : JAD 33
  • Nutrients 23

437 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Motor imagery-based neurofeedback in older adults: neural signatures and feasibility in a randomized controlled trial targeting age-related cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. Journal of NeuroEngineering and Rehabilitation 2026-02-25 Prevention trials

    Although a substantial proportion of TG participants achieved high MI accuracy values, statistical analyses revealed no cognitive improvements specific to TG, suggesting limited efficacy of the MI-based protocol compared to classical cognitive stimulation.

  2. Berry Consumption and Its Role in the Modulation of Obesity and Mild Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Nutrients 2026-02-19 Mild cognitive impairment

    Most dementias are preceded by mild cognitive impairment (MCI), a transitional clinical stage characterized by cognitive decline that does not yet significantly interfere with activities of daily living.

  3. Chronic caffeine consumption prevents obesity-induced cognitive and memory impairments by reducing neuroinflammation and enhancing neuronal activity in the hippocampus

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Pharmacological Research 2026-02-13 Inflammation and the immune system

    Obesity and its associated metabolic disturbances increase the risk of cognitive decline, dementia, and anxiety-related disorders.

  4. Prevention of cognitive decline and dementia: Current evidence on lifestyle factors and dietary patterns

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. EXCLI journal 2026-01-25 Prevention trials

    Cognitive decline and dementia represent major and growing global health challenges, driven largely by population aging and increased longevity.

  5. Cognitive changes and emotional heart rate variability dynamics in subjective cognitive decline: An exploratory longitudinal neuropsychophysiological study

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Acta Psychologica 2026-01-23 Mild cognitive impairment

    Subjective cognitive decline (SCD) is increasingly recognised as a potential preclinical stage of Alzheimer's disease, yet the physiological mechanisms underlying its progression remain poorly understood.

  6. Cognitive–exercise dual-task training delays natural aging/d-galactose-induced cognitive decline in mice

    ✓ Peer-reviewed alzhub usefulness score 33 out of 100. Cellular & Molecular Biology Letters 2026-01-23 Prevention trials

    Age-related upregulation in microRNA (miR)-204 and downregulation in long noncoding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) were observed to disrupt Ephrin-B1 (EFNB1)/EphB2 interactions, leading to reduced cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway activation.

  7. The Application of Artificial Intelligence to Older Adults With Disabilities: A Scoping Review

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of Applied Gerontology 2026-01-20 Digital health tools

    ObjectiveTo review the application of artificial intelligence (AI) in the care of older adults with disabilities, identifying intervention type, target populations, and effects.

  8. Treating Hearing Loss With Hearing Aids for the Prevention of Cognitive Decline and Dementia

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Neurology 2026-01-14 Prevention and risk

    Across imputed data sets, a median of 2,777 eligible individuals were included, with a median of 664 receiving a new HA prescription.

  9. Neuropathologic Profiles and Associated Cognitive Trajectories in Community-Living Older Adults

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. JAMA Network Open 2026-01-02 Laboratory science

    Latent neuropathologic profiles were identified using hierarchical clustering, and longitudinal cognitive trajectories associated with each profile were estimated using functional mixed-effects models.

  10. The average MIND-NL scores for the short FFQ (8·4 ( sd 1·8) points) and food records (6·7 ( sd 1·7) points) showed to be significantly different ( P 0·20) were observed for 10 out of 15 MIND-NL diet components.

  11. Effect of a 24-week resistance exercise intervention on cognitive function in cognitively normal older adults: The AGUEDA randomized controlled trial

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Alzheimer's & Dementia 2026 Prevention and risk

    Although no overall EF benefit was observed, RE improved attentional/inhibitory control in cognitively normal older adults.

  12. Impact of cognitive training on claims‐based diagnosed dementia over 20 years: evidence from the ACTIVE study

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Alzheimer s & Dementia Translational Research & Clinical Interventions 2026-01-01 Prevention trials

    Cognitive training involving speed of cognitive processing has the potential to delay the diagnosis of ADRD.

  13. Resistance training and subcortical vascular cognitive impairment: A 12-month randomized trial

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Alzheimer's & Dementia 2026 Treatments

    PRT may have a small beneficial effect on cognitive function in SVCI.

  14. Remote assessments of sleep and cognition in cognitively normal older adults at risk for Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Sleep Medicine 2025-12-19 Genetics

    At the between-person level, no associations were observed between sleep and cognition.

  15. Impact of multidomain lifestyle intervention on dynamics of cognitive frailty: post hoc analysis of the FINGER trial

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. The Journals of Gerontology Series A 2025-12-12 Prevention trials

    At baseline, 219 participants (18%) had CF. The risk for developing CF at 2 years was higher in the control group (risk ratio [RR], 1.88, p = .003).

  16. REMINDER program: a randomized controlled trial protocol of a neuropsychological intervention for lifestyle modification in older adults at risk of dementia

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. BMC Geriatrics 2025-12-10 Cognitive tests and assessment

    The REMINDER program contributes to dementia prevention research by combining cognitive, lifestyle, and psychosocial strategies within a group-based format, aiming to foster long-term adherence to brain-protective behaviors.

  17. =3.40; P=.04). Greater cognitive improvements were associated with younger age, higher functional status, and lower baseline cognitive function.

  18. Association of neighbourhood walkability with pathophysiological markers and depressive symptoms by area deprivation index and cognitive status in older adults

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Alzheimer s & Dementia 2025-12-01 Risk factors

    Participants' age ranged from 45 to 87, 53% were women, and 26% were diagnosed with dementia (39% AD, 18% Lewy Body and 17% Frontotemporal Dementia; Table 1).

  19. Behavioral and neuronal substrates of serious game‐based computerized cognitive training in cognitive decline related to Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Alzheimer s & Dementia 2025-12-01 Prevention trials

    Significant improvement over time was observed in aggregated domain specific composite scores of episodic and semantic memory and spatial abilities.

  20. Community Matters: How Neighborhood Cohesion Buffers Against Cognitive Impairment via Mental Health Pathways in Black Older Adults

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Alzheimer s & Dementia 2025-12-01 Risk factors

    The overall sample (N =329) was predominantly female (76.4%) with a mean age of 64.5 (range 45-92) and an average of 14.9 years of education (Table 1).

  21. Hearing Impairment, Hearing Aid Use, and Cognitive Outcomes in Older Adults: A Cross‐Sectional Study

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Alzheimer s & Dementia 2025-12-01 Risk factors

    Participants with impaired hearing (n = 179) were older (73.9 vs. 71.4 years, p <0.001), often male (61.5% vs. 36.5%, p <0.001), and had lower cognitive scores than normal-hearing individuals (n = 241).

  22. Mediterranean diet, gut microbiota, and cognitive decline in older adults with obesity/overweight and metabolic syndrome: a prospective cohort study

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. BMC Medicine 2025-12-01 Prevention trials

    Higher adherence to the MedDiet was associated with greater gut microbial diversity (p < 0.05) and distinct microbial composition (PERMANOVA, p = 0.001).

  23. Multidomain intervention for preventiing cognitive decline among older adults with mild cognitive impairment ‐ Interim results from TINAGE trial

    ✓ Peer-reviewed alzhub usefulness score 30 out of 100. Alzheimer s & Dementia 2025-12-01 Prevention trials

    During the one-year follow-up, the intervention group showed a significant increase in mean cognitive scores (Addenbrooke's cognitive examination), rising from 73.94 to 82.32 (p < 0.001).

  24. Multilevel and Multidimensional Features of Socioeconomic Status and Cognitive Function in Older Adulthood: Findings from the IGNITE Study

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Alzheimer s & Dementia 2025-12-01 Risk factors

    Lower objective SES was associated with poorer performance on all cognitive domains: episodic memory (β = 0.115, p = 0.003), executive function (β = 0.210, p 0.05).

  25. Neighborhood Disadvantage and Cognitive Function: The Moderating Role of Self-reported Loneliness

    ✓ Peer-reviewed alzhub usefulness score 32 out of 100. Innovation in Aging 2025-12-01 Risk factors

    Overall, our findings suggest that greater neighborhood disadvantage may influence select domains of memory, and that one’s self-reported loneliness may influence how this relationship manifests.

  26. Neighborhood walkability, healthy food environments, and cognitive decline over 14 years among midlife women: Study of Women's Health Across the Nation

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Alzheimer s & Dementia 2025-12-01 Risk factors

    Women living in areas with higher walkability showed slower rates of decline in immediate (estimate=0.019, SE=0.009) and delayed recall (estimate=0.018, SE=0.008) (Figure 1).

  27. Relationship of cognition and structured grocery shopping in older adults with and without mild cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 35 out of 100. Alzheimer s & Dementia 2025-12-01 Risk factors

    Age was similar between groups (p = 0.07).

  28. The America I Know Could Use a Good Cry: Impact of State and Civilian‐Perpetrated Racial Violence on Cognitive Health

    ✓ Peer-reviewed alzhub usefulness score 35 out of 100. Alzheimer s & Dementia 2025-12-01 Risk factors

    Participants racialized as Black living in a county with a history of lynching, disproportionate police killings, and disproportionate jail and prison incarceration were 2.8 (95%CI [-0.003, 5.834]) times more likely to have at least one incident of cognitive impairment between 2008-2020 compared to participants racialized as Black living in a county with a history of lynching and disproportionate police killings but not disproportionate incarceration.

  29. The association of neighborhood deprivation with sleepiness among cognitively normal older adults with and without subjective cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Alzheimer s & Dementia 2025-12-01 Risk factors

    Among the study population at large, there was a statistically significant association between ADI and ESS scores (β = 0.490, 95% CI [0.138, 0.842], p = 0.007).

  30. Association of Daily Driving Behaviors With Mild Cognitive Impairment in Older Adults Followed Over 10 Years

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Neurology 2025-11-26 Getting a diagnosis

    Among 298 participants (MCI, n = 56; NC, n = 242; mean age 75.1 years; 45.6% female), the groups were similar in age, sex, race, and APOE ε4 status at baseline, as well as in most driving behaviors.

  31. MIND diet adherence and cognitive function in Alzheimer's disease: Mediating roles of neural oscillatory markers from resting‐state EEG

    ✓ Peer-reviewed alzhub usefulness score 37 out of 100. Psychiatry and Clinical Neurosciences 2025-11-19 Prevention trials

    MIND scores were significantly lower in the AD group (P < 0.001).

  32. Cognitive Age Delta as a Marker of Healthy and Pathological Cognitive Aging: The Role of Lifestyle, Cognitive Reserve, and Vascular Risk

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of Clinical Medicine 2025-11-18 Genetics

    CAD did not differ across biomarker groups (Kruskal–Wallis H(2) = 0.17, p = 0.91).

  33. Challenging the Wine Component in Mediterranean Diet Scores: Cognitive Outcomes in Portuguese Adults at High Risk of Dementia

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Nutrients 2025-11-15 Cognitive tests and assessment

    MEDAS-R was positively associated with better MMSE performance (p = 0.043) and showed a borderline association with the MoCA (p = 0.051), but not with the ACE-R score (p = 0.356).

  34. Mild Cognitive Impairment and Sarcopenia: Effects of Resistance Exercise Training on Neuroinflammation, Cognitive Performance, and Structural Brain Changes

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. International Journal of Molecular Sciences 2025-11-14 Mild cognitive impairment

    Mild cognitive impairment (MCI) and sarcopenia are prevalent age-related conditions that often coexist and share common mechanisms such as chronic inflammation, reduced neuroplasticity, and impaired muscle function.

  35. Can a Mediterranean diet prevent cognitive decline?

    ✓ Peer-reviewed alzhub usefulness score 33 out of 100. Zenodo (CERN European Organization for Nuclear Research) 2025-11-11 Prevention trials

    Current evidence suggests a potential for the Mediterranean diet to prevent cognitive decline, largely supported by observational studies, although randomized controlled trials show mixed results.

  36. Can a Mediterranean diet prevent cognitive decline?

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Zenodo (CERN European Organization for Nuclear Research) 2025-11-11 Prevention trials

    Current evidence suggests a potential for the Mediterranean diet to prevent cognitive decline, largely supported by observational studies, although randomized controlled trials show mixed results.

  37. A Causal Association Between Drug Use and Cognitive Impairment: A Two‐Sample Mendelian Randomization Study

    ✓ Peer-reviewed alzhub usefulness score 34 out of 100. Brain and Behavior 2025-11-01 Genetics

    The IVW analysis indicated that antithrombotic agents (odds ratio [OR] = 2.12, 95% confidence interval [CI] = 1.03-4.34, p = 0.04), HMG CoA reductase inhibitors (OR = 1.36, 95% CI = 1.07-1.72, p = 0.01), and salicylic acid and derivatives (OR = 2.77, 95% CI = 1.44-5.32, p = 0.002) are a strong risk factor for dementia with Lewy bodies (DLB); diuretics (OR = 1.13, 95% CI = 1-1.27, p = 0.047) and calcium channel blockers (OR = 1.16, 95% CI = 1.04-1.29, p = 0.007) might be a risk factor for vascular dementia; thyroid preparations (OR = 1.03, 95% CI = 1.01-1.06, p = 0.01), diuretics (OR = 1.06, 95% CI = 1.02-1.11, p = 0.004), and immunosuppressants (OR = 1.07, 95% CI = 1.01-1.12, p = 0.001), are a risk factor for frontotemporal dementia; HMG CoA reductase inhibitors is a risk factor for dementia in Alzheimer disease (OR = 1.32, 95% CI = 1.05-1.65, p = 0.01).

  38. Efficacy of a multidomain intervention in older adults with vascular risks: The Japan‐Multimodal Intervention Trial for the Prevention of Dementia (J‐MINT)

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Alzheimer s & Dementia 2025-11-01 Prevention trials

    Among the participants, 298 had at least one untreated or uncontrolled VRF.

  39. A total of 346 of 374 (92.5%) intervention arm participants received some intervention (reach), and 305 of 374 (81.6%) attended ≥5 main sessions (predefined as adhering: dose).

  40. Brain age gap as a predictive biomarker that links aging, lifestyle, and neuropsychiatric health

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Communications Medicine 2025-10-24 Prevention and risk

    The highest-risk group (Q4) shows a 2.8-fold increased risk of Alzheimer’s disease, a 6.4-fold risk of multiple sclerosis, and a 2.4-fold higher mortality risk.

  41. Faith-Based Lifestyle Intervention for Diabetes Prevention Among Adults in Bangladesh

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. JAMA Network Open 2025-10-20 Prevention and risk

    Of the 799 participants (mean [SD] age, 46.2 [11.6] years; 424 women [53.1%]) randomized, 641 completed the 12-month follow-up and were included in the intention-to-treat analysis: 341 (n = 4 mosques) in the intervention group and 300 (n = 4 mosques) in the control group.

  42. Harmonized Cognitive Assessment Protocol: What makes an HCAP an HCAP? An adaptive architecture for measuring cognitive aging around the world

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. The Journals of Gerontology Series B 2025-10-18 Getting a diagnosis

    To balance high-quality measurement of cognitive domains and maintain the ability to perform meaningful cross-national comparisons, each HCAP should include a common set of at least three to four continuously distributed test items per domain that can link domains across studies.

  43. Change in QoL (decreased, maintained or improved) was determined using a cross-tabulation test.

  44. The measurement of cognition in large-scale cross-national surveys: lessons from the Health and Retirement Study International Network of Studies and the Harmonized Cognitive Assessment Protocol

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. The Journals of Gerontology Series B 2025-10-16 Getting a diagnosis

    These lessons emphasize the importance of ensuring tests are feasible across both high-income countries and LMICs, maintaining consistency within studies and over time, and designing comprehensive cognitive batteries for improved measurement precision of general and domain-specific phenotypes.

  45. Linking nutrition and aging: A cross-domain analysis of Mediterranean Diet Adhesion Screener components

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Mechanisms of Ageing and Development 2025-10-15 Prevention trials

    This study explores the scientific landscape linking the Mediterranean Diet Adherence Screener (MEDAS) to aging-related health outcomes through a comprehensive bibliometric and scoping review approach.

  46. Social isolation and cognitive decline in older adults: a longitudinal study across 24 countries

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. BMC Geriatrics 2025-10-14 Risk factors

    Social isolation was significantly associated with reduced cognitive ability (pooled effect = -0.07, 95% CI = -0.08, -0.05), with consistently negative effects across memory, orientation, and executive ability.

  47. Among the 92 participants in the ITT population (mean age 71.9 years; mean education 16.5 years; 61/92, 66%, women; 88/92, 96%, White), 82 (89%) completed all study activities.

  48. Cognitive Outcomes After Hip Fracture Surgery: The Association of Postoperative Delirium on Previously Cognitively Normal Older Adults

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. American Journal of Geriatric Psychiatry 2025-10-11 Cognitive tests and assessment

    36.5% of the overall cohort experienced delirium.

  49. Impact of Conservative Management vs. Dialysis Transition on Cognition in a National Cohort of Patients with Advanced CKD

    ✓ Peer-reviewed alzhub usefulness score 35 out of 100. Journal of the American Society of Nephrology 2025-10-01 Health systems and care delivery

    In 18,383 CM patients PS-matched to 18,383 dialysis patients, unadjusted Cox models showed dialysis transition was associated with higher risk of dementia, MCI, or combined dementia/MCI vs. CM: HRs (95%CIs) 1.40 (1.32-1.48), 1.64 (1.46, 1.85), and 1.42 (1.34, 1.49).

  50. High Physical Fitness Is Associated With Better Cognitive Function in Older Adults With Dementia: A Cross-Sectional Study

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Aging and Physical Activity 2025-09-30 Cognitive tests and assessment

    A higher GPF was associated with better cognitive function in institutionalized older adults with dementia.

From across this tag

8 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 8. The same 8 appear here every time.

All topic tags with their study counts