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Multilevel and Multidimensional Features of Socioeconomic Status and Cognitive Function in Older Adulthood: Findings from the IGNITE Study
Jermon A. Drake, Lu Wan, Peter J. Gianaros, Patricio Solis‐Urra, Haiqing Huang, Rebecca G. Reed, Charles H. Hillman, Eric D. Vidoni et al.. Alzheimer s & Dementia, 2025-12-01
Topic: Risk, prevention and care in population studies
Lower objective SES was associated with poorer performance on all cognitive domains: episodic memory (β = 0.115, p = 0.003), executive function (β = 0.210, p 0.05). When examining all SES indicators simultaneously, only the objective SES composite remained significantly associated with cognitive function. In secondary models, the objective SES composite score explained additional variance beyond education, income, and their standardized average. Objective SES showed the broadest and most robust associations with cognitive function relative to subjective and area-level indicators among cognitively normal older adults. Future studies may benefit from examining multiple financial indicators to better detect the extent and magnitude of cognitive deficits related to socioeconomic disadvantage in older adulthood.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Drake, J. A., Wan, L., Gianaros, P. J., Solis‐Urra, P., Huang, H., Reed, R. G., et al. (2025). Multilevel and Multidimensional Features of Socioeconomic Status and Cognitive Function in Older Adulthood: Findings from the IGNITE Study. Alzheimer s & Dementia. https://doi.org/10.1002/alz70861_108795
Vancouver
Drake JA, Wan L, Gianaros PJ, Solis‐Urra P, Huang H, Reed RG, et al. Multilevel and Multidimensional Features of Socioeconomic Status and Cognitive Function in Older Adulthood: Findings from the IGNITE Study. Alzheimer s & Dementia. 2025. doi:10.1002/alz70861_108795. PMID: 41433634.
BibTeX
@article{drake2025-41433634,
author = {Drake, Jermon A. and Wan, Lu and Gianaros, Peter J. and Solis‐Urra, Patricio and Huang, Haiqing and Reed, Rebecca G. and Hillman, Charles H. and Vidoni, Eric D. and others},
title = {{Multilevel and Multidimensional Features of Socioeconomic Status and Cognitive Function in Older Adulthood: Findings from the IGNITE Study}},
journal = {Alzheimer s \& Dementia},
year = {2025},
doi = {10.1002/alz70861_108795},
pmid = {41433634},
url = {https://doi.org/10.1002/alz70861_108795}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
Key findings
- Lower objective SES was associated with poorer performance on all cognitive domains: episodic memory (β = 0.115, p = 0.003), executive function (β = 0.210, p 0.05).
- When examining all SES indicators simultaneously, only the objective SES composite remained significantly associated with cognitive function.
- In secondary models, the objective SES composite score explained additional variance beyond education, income, and their standardized average.
- Objective SES showed the broadest and most robust associations with cognitive function relative to subjective and area-level indicators among cognitively normal older adults.
- Future studies may benefit from examining multiple financial indicators to better detect the extent and magnitude of cognitive deficits related to socioeconomic disadvantage in older adulthood.
Why it matters
This study found that lower objective socioeconomic status was linked to worse performance across all cognitive domains in cognitively normal older adults. It does not test any treatment, cure, or prevention for Alzheimer's disease.
New to this subject? Start with our plain-English guide: Risk factors, ranked →
Study details
- Study designcross-sectional
- Evidence strengthHigh
How this study scored 41/100
Published in a peer-reviewed journal, and it is a snapshot of people at one point in time. Scored zero for sample size, effect reported, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Alzheimer s & Dementia) |
| Journal's citation record | 2 / 4 | Alzheimer s & Dementia: journal h-index 228 (OpenAlex, 2026-10-29) |
| Study design | 4 / 12 | A snapshot of people at one point in time |
| Strength of evidence | 5 / 5 | Rated “high” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 0 / 7 | Cited 0 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.0 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 0 / 6 | Cited 0.0× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 0 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Lauren E. Oberlin: h-index 20 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | University of Pittsburgh: institution h-index 1,470 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 8 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 41433634) |
| Free to read | 2 / 2 | Free to read |
| Total | 41 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1002/alz70861_108795
- PubMed: 41433634
- Original source →
- Free full text: Alzheimer s & Dementia →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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