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REMINDER program: a randomized controlled trial protocol of a neuropsychological intervention for lifestyle modification in older adults at risk of dementia
Ana Rita Silva, Catarina Baptista, Inês Baldeiras, Maria Salomé Pinho, Margarida Lima, Rosa Marina Afonso. BMC Geriatrics, 2025-12-10
Topic: Risk, prevention and care in population studies
The REMINDER program contributes to dementia prevention research by combining cognitive, lifestyle, and psychosocial strategies within a group-based format, aiming to foster long-term adherence to brain-protective behaviors. Nevertheless, challenges are anticipated, including participant heterogeneity, adherence to lifestyle change, potential drop-out during follow-up, and the complexity of monitoring multiple outcomes. Addressing these limitations will be crucial to inform the future scalability and sustainability of dementia prevention interventions. TRIAL REGISTRATION: ClinicalTrial.gov Identifier NCT05296980, 22/02/2022).
Key findings
- The REMINDER program contributes to dementia prevention research by combining cognitive, lifestyle, and psychosocial strategies within a group-based format, aiming to foster long-term adherence to brain-protective behaviors.
- Nevertheless, challenges are anticipated, including participant heterogeneity, adherence to lifestyle change, potential drop-out during follow-up, and the complexity of monitoring multiple outcomes.
- Addressing these limitations will be crucial to inform the future scalability and sustainability of dementia prevention interventions.
- TRIAL REGISTRATION: ClinicalTrial.gov Identifier NCT05296980, 22/02/2022).
Why it matters
This is a protocol describing a planned randomized trial of a group program combining cognitive, lifestyle and psychosocial strategies for older adults at risk of dementia. Because it reports no results yet, it cannot show whether the program prevents dementia.
Study details
- Participants270
- Evidence strengthHigh
How this study scored 43/100
Published in a peer-reviewed journal. Scored zero for study design and effect reported because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (BMC Geriatrics) |
| Journal's citation record | 2 / 4 | BMC Geriatrics: journal h-index 153 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 5 / 5 | Rated “high” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 2 / 4 | 270 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 1 / 2 | Randomised (as stated in the record) |
| Times cited | 1 / 7 | Cited 1 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.3 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 1 / 6 | Cited 0.6× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 1 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 1 / 4 | Last-listed author Rosa Marina Afonso: h-index 17 (OpenAlex, whole career) |
| Institution's track record | 0 / 3 | University of Coimbra: institution h-index 515 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 4 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 41366742) |
| Free to read | 2 / 2 | Free to read |
| Total | 43 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
APA 7th
Silva, A. R., Baptista, C., Baldeiras, I., Pinho, M. S., Lima, M., & Afonso, R. M. (2025). REMINDER program: a randomized controlled trial protocol of a neuropsychological intervention for lifestyle modification in older adults at risk of dementia. BMC Geriatrics. https://doi.org/10.1186/s12877-025-06714-x
Vancouver
Silva AR, Baptista C, Baldeiras I, Pinho MS, Lima M, Afonso RM. REMINDER program: a randomized controlled trial protocol of a neuropsychological intervention for lifestyle modification in older adults at risk of dementia. BMC Geriatrics. 2025. doi:10.1186/s12877-025-06714-x. PMID: 41366742.
BibTeX
@article{silva2025-41366742,
author = {Silva, Ana Rita and Baptista, Catarina and Baldeiras, Inês and Pinho, Maria Salomé and Lima, Margarida and Afonso, Rosa Marina},
title = {{REMINDER program: a randomized controlled trial protocol of a neuropsychological intervention for lifestyle modification in older adults at risk of dementia}},
journal = {BMC Geriatrics},
year = {2025},
doi = {10.1186/s12877-025-06714-x},
pmid = {41366742},
url = {https://doi.org/10.1186/s12877-025-06714-x}
}
Studies this one cites
Referenced by this study and also in the alzhub library, so you can read them here. Showing 12 of 15.