Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. A typology of sub-clinical senescent cognitive disorder

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The British journal of psychiatry : the journal of mental science 1996-04-01 Cognitive tests and assessment

    Subclinical cognitive impairment was found to not constitute a unitary phenomenon and heterogeneous subgroups could be differentiated.

  2. A surface-based technique for warping three-dimensional images of the brain

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. IEEE Transactions on Medical Imaging 1996-01-01 Brain scans and imaging

    The authors have devised, implemented, and tested a fast, spatially accurate technique for calculating the high-dimensional deformation field relating the brain anatomies of an arbitrary pair of subjects.

  3. Morning bright light therapy for sleep and behavior disorders in elderly patients with dementia

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Acta Psychiatrica Scandinavica 1994-01-01 Risk factors

    Fourteen inpatients with dementia showing sleep and behavior disorders (average age = 75 years), and 10 control elderly people (average age = 75 years) were carefully observed for 2 months.

  4. Clock completion: an objective screening test for dementia

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of the American Geriatrics Society 1993-11-01 Health systems and care delivery

    A simple, completely objective scoring system for a clock completion test has been developed which involves only the number of digits placed in the fourth quadrant of a pre-drawn circle.

  5. IRAOS: an instrument for the assessment of onset and early course of schizophrenia

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Schizophrenia research 1992-03-01 Clinical safety

    Since Kraepelin's first description of dementia praecox in 1889 many data and theories have been published on the onset and course of schizophrenia.

  6. Detection of abnormal memory decline in mild cases of Alzheimer's disease using CERAD neuropsychological measures

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Archives of neurology 1991-03-01 Risk factors

    The present study was designed to determine which of the memory tasks included in the CERAD (Consortium to Establish a Registry for Alzheimer's Disease) neuropsychological battery best differentiate patients with early Alzheimer's disease from cognitively normal elderly control subjects and also best distinguish between the various levels of severity of the dementia process.

  7. Alterations in the circadian rest-activity rhythm in aging and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Biological psychiatry 1990-03-01 Risk factors

    The suprachiasmatic nucleus, considered to be the endogenous circadian clock in the mammalian brain, shows morphological changes with aging, which become even more pronounced in Alzheimer's disease (AD).

  8. Hearing impairment as a predictor of cognitive decline in dementia

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of the American Geriatrics Society 1988-11-01 Risk factors

    Thirty-eight patients with dementia of various etiologies were studied longitudinally to determine the change in cognition over time in subjects with and without hearing impairment.

  9. Presence of both odor identification and detection deficits in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Brain research bulletin 1987-05-01 Prevention and risk

    Recent studies of Alzheimer's disease patients have demonstrated (a) marked structural and biochemical alterations in brain regions associated with olfactory function (including the olfactory bulb and entorhinal cortex) and (b) decrements in the ability to identify odorants.

  10. A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of the neurological sciences 1987-04-01 Disease mechanisms

    A quantitative morphometric analysis was used to estimate neurone and synapse densities in cerebral cortical biopsy tissues from patients with dementia under 65 years of age and pathologically verified as suffering from Alzheimer's disease.

  11. Subcortical dementia. Review of an emerging concept

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Archives of neurology 1984-08-01 Clinical safety

    Subcortical dementia is a clinical syndrome characterized by slowness of mental processing, forgetfulness, impaired cognition, apathy, and depression.

  12. The dementia of dementia praecox

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Acta Psychiatrica Scandinavica 1978-04-01 Digital health tools

    A group of 18 long‐stay patients with a diagnosis of schizophrenia were compared with a group of 10 age‐matched subjects who had been institutionalized by reason of physical disease, on performance on tests of intellectual function; and with a group of agematched healthy subjects, both on tests of intellectual function, and radiographically, using the technique of computerized axial tomography (EMI scan) of the brain.

  13. The 'subcortical dementia' of progressive supranuclear palsy

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of neurology, neurosurgery, and psychiatry 1974-02-01 Risk factors

    Progressive supranuclear palsy (Steele et al.) has a characteristic pattern of dementia: (1) forgetfulness, (2) slowing of thought processes, (3) emotional or personality changes (apathy or depression with occasional outbursts of irritability), and (4) impaired ability to manipulate acquired knowledge.

  14. Ophthalmoplegia Plus

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Archives of Neurology 1968-06-01 Brain scans and imaging

    CONSIDERABLE interest has been focused on the entity of progressive external ophthalmoplegia (PEO) since the report of Kiloh and Nevin in 1951.1These authors were primarily concerned with the pathogenesis of the ocular muscle weakness, concluding that it was virtually always the result of a myopathic process.

  15. Bilingualism and cognition

    ✓ Peer-reviewed alzhub usefulness score 34 out of 100. Bilingualism Language and Cognition 2014-11-27 Risk factors

    The relation between bilingualism and cognition is informative about the connection between language and mind.

  16. Analysis of spontaneous, conversational speech in dementia of Alzheimer type: Evaluation of an objective technique for analysing lexical performance

    ✓ Peer-reviewed alzhub usefulness score 34 out of 100. Aphasiology 2000-01-01 Digital health tools

    Spontaneous, conversational speech in probable dementia of Alzheimer type (DAT) participants and healthy older controls was analysed using eight linguistic measures.

  17. Studying bilinguals: Methodological and conceptual issues

    ✓ Peer-reviewed alzhub usefulness score 34 out of 100. Bilingualism Language and Cognition 1998-08-01 Risk factors

    Because the field of bilingualism is still relatively new, studies in the linguistics, psycholinguistics, language development and neurolinguistics of bilingualism have often produced conflicting results.

  18. A hindi version of the MMSE: The development of a cognitive screening instrument for a largely illiterate rural elderly population in india

    ✓ Peer-reviewed alzhub usefulness score 34 out of 100. International Journal of Geriatric Psychiatry 1995-05-01 Risk factors

    The Indo‐US Cross‐National Dementia Epidemiology Study seeks to compare two rural populations, in the US and India: the Monongahela Valley, a rural community of relatively low socioeconomic status in southwestern Pennsylvania (USA), and Ballabgarh, a rural community near New Delhi in North India.

  19. Developments in the concept of working memory

    ✓ Peer-reviewed alzhub usefulness score 34 out of 100. Neuropsychology 1994-01-01 Digital health tools

    The authors summarize developments in the concept of working memory as a multicomponent system, beginning by contrasting this approach with alternative uses of the term working memory.

  20. Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Research Square 2026-11-01 Mild cognitive impairment

    Among 10,489 participants with incident MCI, the mean age at the incident MCI wave was 70.6 years (SD = 11.53), and 56.6% were female.

  21. Repetitive negative thinking is associated with amyloid accumulation over 3 years in cognitively healthy adults

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-10-31 Brain scans and imaging

    RNT was associated with increasing global amyloid accumulation even after controlling for psychological symptoms (B = 0.0120, 95% Confidence Interval 0.003 to 0.021, P = 0.012), and in sensitivity analyses limited to participants aged ≥50 or ≥60.

  22. A Wasserstein Weisfeiler-Lehman Kernel Framework for Multimodal Brain Connectome Analysis

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Research Square 2026-10-29 Brain scans and imaging

    Under nested cross-validation, the WWL kernel achieves a balanced accuracy of $0.651\pm0.028$, significantly outperforming both a raw-feature SVM and a histogram-based WL-kernel baseline.

  23. Cognition in healthy aging, ages 36 to 108: Associations with dementia risk factors and neurodegenerative disease biomarkers

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-10-28 Biomarkers

    Most evidence on dementia risk factors comes from older or clinical samples, leaving their relation to normal cognitive aging unclear.

  24. From group-level neurophysiological biomarkers to individual-level phenotyping to identify mechanisms of neurodegenerative disease

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. bioRxiv 2026-10-28 Brain scans and imaging

    Precision medicine approaches require physiological effects to be informative when translated to the individual.

  25. Geographic Heterogeneity in the Association Between Schooling and Cognitive Change Among Older Adults in India

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-10-28 Risk factors

    Higher educational attainment is associated with steeper measured cognitive decline among older adults in India, but whether this association is uniform across the country is unknown.

From across this topic

10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

Other topics