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  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
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In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. Network dysfunction in Alzheimer's disease and frontotemporal dementia: implications for psychiatry

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Biological psychiatry 2014-02-04 Brain scans and imaging

    Structural and functional connectivity methods are changing how researchers conceptualize and explore neuropsychiatric disease.

  2. Latent feature representation with stacked auto-encoder for AD/MCI diagnosis

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Brain structure & function 2013-12-22 Digital health tools

    Recently, there have been great interests for computer-aided diagnosis of Alzheimer's disease (AD) and its prodromal stage, mild cognitive impairment (MCI).

  3. Right hemisphere role in cognitive reserve

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of aging 2013-12-04 Digital health tools

    High levels of education, occupational complexity, and/or premorbid intelligence are associated with lower levels of cognitive impairment than would be expected from a given brain pathology.

  4. Cognitive deficits in geriatric depression: clinical correlates and implications for current and future treatment

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Psychiatric clinics of North America 2013-10-06 Cognitive tests and assessment

    The purpose of this article is to identify the cognitive deficits commonly associated with geriatric depression and describe their clinical significance.

  5. Efficiency, capacity, compensation, maintenance, plasticity: emerging concepts in cognitive reserve

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Trends in cognitive sciences 2013-09-07 Risk factors

    Cognitive reserve (CR) is a concept meant to account for the frequent discrepancy between an individual's measured level of brain pathology and her expected cognitive performance.

  6. A prospective 14-year longitudinal follow-up of dementia in persons with Down syndrome

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of intellectual disability research : JIDR 2013-07-31 Down syndrome and Alzheimer's

    The previously reported high risk levels for dementia among people with Down syndrome was confirmed in these data as was the value of the instruments utilised in tracking decline and helping to confirm diagnosis even in persons with severe intellectual disability.

  7. Energetic cost of brain functional connectivity

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2013-07-29 Brain scans and imaging

    The brain's functional connectivity is complex, has high energetic cost, and requires efficient use of glucose, the brain's main energy source.

  8. Using resting state functional connectivity to unravel networks of tinnitus

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Hearing research 2013-07-26 Risk factors

    Resting state functional connectivity (rs-fc) using fMRI has become an important tool in examining differences in brain activity between patient and healthy populations.

  9. Functional neuroanatomy of the central noradrenergic system

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of psychopharmacology (Oxford, England) 2013-06-12 Risk factors

    The central noradrenergic neurone, like the peripheral sympathetic neurone, is characterized by a diffusely arborizing terminal axonal network.

  10. Eye movements in patients with neurodegenerative disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nature reviews. Neurology 2013-01-22 Brain scans and imaging

    The neural pathways and brain regions involved in eye movements during ocular fixation and gaze control include the cerebrum, brainstem and cerebellum, and abnormal eye movements can indicate the presence of neurodegeneration.

  11. Resting state functional connectivity in preclinical Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Biological psychiatry 2013-01-04 Brain scans and imaging

    There has been a dramatic increase in the number of studies using resting state functional magnetic resonance imaging (rs-fMRI), a recent addition to imaging analysis techniques.

  12. Random forest-based similarity measures for multi-modal classification of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. NeuroImage 2012-10-04 Digital health tools

    Neurodegenerative disorders, such as Alzheimer's disease, are associated with changes in multiple neuroimaging and biological measures.

  13. Abnormal network connectivity in frontotemporal dementia: evidence for prefrontal isolation

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2012-09-24 Digital health tools

    The present findings support a theory of FTD as a disorder of frontolimbic disconnection leading to unconstrained prefrontal connectivity.

  14. Subjective cognitive complaints and amyloid burden in cognitively normal older individuals

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuropsychologia 2012-08-23 Brain scans and imaging

    Accumulating evidence suggests that subjective cognitive complaints (SCC) may indicate subtle cognitive decline characteristic of individuals with preclinical Alzheimer's disease (AD).

  15. Spatial navigation in normal aging and the prodromal stage of Alzheimer's disease: insights from imaging and behavioral studies

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Ageing research reviews 2012-07-05 Digital health tools

    Normal aging and mild Alzheimer's disease (AD) are associated with declines in navigational skills, including allocentric and egocentric representations, cognitive mapping, landmark processing, and spatial memory.

  16. The clinical problem of symptomatic Alzheimer disease and mild cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Cold Spring Harbor perspectives in medicine 2012-05-01 Getting a diagnosis

    Alzheimer disease (AD) is the most common cause of dementia in the elderly.

  17. Bilingualism: consequences for mind and brain

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Trends in cognitive sciences 2012-04-01 Risk factors

    Building on earlier evidence showing a beneficial effect of bilingualism on children's cognitive development, we review recent studies using both behavioral and neuroimaging methods to examine the effects of bilingualism on cognition in adulthood and explore possible mechanisms for these effects.

  18. Concurrent impairments in sleep and memory in amnestic mild cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of the International Neuropsychological Society : JINS 2012-02-03 Risk factors

    Whereas patients with Alzheimer's disease (AD) experience difficulties forming and retrieving memories, their memory impairments may also partially reflect an unrecognized dysfunction in sleep-dependent consolidation that normally stabilizes declarative memory storage across cortical areas.

  19. Using Support Vector Machine to identify imaging biomarkers of neurological and psychiatric disease: a critical review

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuroscience and biobehavioral reviews 2012-01-28 Risk factors

    Standard univariate analysis of neuroimaging data has revealed a host of neuroanatomical and functional differences between healthy individuals and patients suffering a wide range of neurological and psychiatric disorders.

  20. Essential tremor: beyond the motor features

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Parkinsonism & related disorders 2012-01-02 Risk factors

    There is a growing evidence to suggest that apart from motor features, patients with Essential Tremor (ET) may have significant non-motor features.

  21. Guidelines for management of idiopathic normal pressure hydrocephalus: second edition

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurologia medico-chirurgica 2012-01-01 Digital health tools

    Among the various disorders manifesting dementia, gait disturbance, and urinary incontinence in the elderly population, idiopathic normal pressure hydrocephalus (iNPH) is becoming of great importance.

  22. Does feature selection improve classification accuracy? Impact of sample size and feature selection on classification using anatomical magnetic resonance images

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. NeuroImage 2011-12-01 Digital health tools

    There are growing numbers of studies using machine learning approaches to characterize patterns of anatomical difference discernible from neuroimaging data.

  23. Multi-modal multi-task learning for joint prediction of multiple regression and classification variables in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. NeuroImage 2011-10-04 Brain scans and imaging

    Many machine learning and pattern classification methods have been applied to the diagnosis of Alzheimer's disease (AD) and its prodromal stage, i.e., mild cognitive impairment (MCI).

  24. Gait and cognition: the relationship between gait stability and variability with executive function in persons with and without dementia

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Gait & posture 2011-10-02 Digital health tools

    Besides cognitive decline, dementia is characterized by gait changes and increased fall risk, also in early stages of the disease.

  25. Visual symptoms in Parkinson's disease and Parkinson's disease dementia

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Movement disorders : official journal of the Movement Disorder Society 2011-09-27 Risk factors

    Visual symptoms are common in PD and PD dementia and include difficulty reading, double vision, illusions, feelings of presence and passage, and complex visual hallucinations.

From across this topic

10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

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