Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.

Highest usefulness score first. Studies without a score come last.

  1. Brain Network Connectivity Mediates Education-related Cognitive Performance in Healthy Elderly Adults

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Current Alzheimer research 2019 Brain scans and imaging

    We found that education level was positively associated with a wide range of complex cognitive domains including general mental status, episodic memory, language, attention, executive function and visuospatial processing, and it showed significantly negative correlations with FC of multiple areas in the Default Mode Network (DMN) and Left Frontal-parietal Network (LFP) which are related to complex cognition.

  2. Sleep physiology and disorders in aging and dementia

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Handbook of clinical neurology 2019 Risk factors

    Sleep problems occur commonly in normal and pathologic aging.

  3. [Sleep and cognitive impairment in neurodegenerative diseases]

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 2019 Risk factors

    Sleep and wakefulness disorders are commonly seen in patients with Parkinson's disease, Lewy body dementia and Alzheimer's disease.

  4. Role of Obstructive Sleep Apnea in Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. International journal of head and neck surgery 2019 Risk factors

    Obstructive sleep apnea (OSA) is a prevalent sleep related breathing disorder characterized by repetitive collapse of the upper airways leading to intermittent hypoxia and sleep disruption.

  5. [Presbyacusis]

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Vestnik otorinolaringologii 2019 Risk factors

    In the world, the spread of hearing loss due to age is an important socio-medical problem.

  6. Cognitive reserve and dementia A scientometric review

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Dementia & neuropsychologia 2019 Risk factors

    Research into cognitive reserve (CR) and dementia is advancing rapidly.

  7. Bilingualism and Dementia: Cognitive Reserve to Linguistic Competency

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Journal of Alzheimer's disease : JAD 2019 Risk factors

    Despite the large number of elderly bilinguals at risk for Alzheimer's disease (AD) and dementia worldwide, significant questions remain about the relationship between speaking more than one language and later cognitive decline.

  8. Cognitive Reserve in Midlife is not Associated with Amyloid-β Deposition in Late-Life

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Journal of Alzheimer's disease : JAD 2019 Risk factors

    We examined associations between cognitive reserve and late-life amyloid-β deposition using florbetapir positron emission tomography (PET).

  9. Exercise and the Aging Brain: Considerations for Sex Differences

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Brain plasticity (Amsterdam, Netherlands) 2018-12-12 Prevention trials

    Engaging in targeted exercise interventions is a promising, non-pharmacological strategy to mitigate the deleterious effects of aging and disease on brain health.

  10. Exercise Improves Vascular Function, but does this Translate to the Brain?

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Brain plasticity (Amsterdam, Netherlands) 2018-12-12 Prevention trials

    The number of adults with Alzheimer's disease (AD) or related dementia is expected to increase exponentially.

  11. Montreal cognitive assessment reflects cognitive reserve

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. BMC geriatrics 2018-10-30 Risk factors

    The MoCA reflected total CRIq score (CRI; B = 0.076, P < 0.001), CRI-Education (B = 0.066, P < 0.001), and CRI-Working activity (B = 0.025, P = 0.042), while MMSE reflected total CRI (B = 0.044, P < 0.001) and CRI-Education (B = 0.049, P < 0.001) only.

  12. Polygenic Score for Alzheimer Disease and cognition: The mediating role of personality

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Journal of psychiatric research 2018-10-23 Genetics

    Alzheimer's disease (AD) polygenic risk score (PGS) is associated with lower cognitive functioning even among older individuals without dementia.

  13. Default Mode Network Complexity and Cognitive Decline in Mild Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Frontiers in neuroscience 2018-10-23 Brain scans and imaging

    The default mode network (DMN), one of so-called resting-state networks, has been associated with cognitive processes that are directed toward the self, such as introspection and autobiographic memory.

  14. Cognitive Reserve Relates to Functional Network Efficiency in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Frontiers in aging neuroscience 2018-08-21 Risk factors

    Alzheimer's disease (AD) is the most common form of dementia, with no means of cure or prevention.

  15. Traumatic Brain Injury, Chronic Traumatic Encephalopathy, and Alzheimer Disease

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Clinics in geriatric medicine 2018-08-21 Costs and economics

    Traumatic brain injury (TBI) is a major health and economic burden.

  16. Functional and structural connectivity of the amygdala underpins locus of control in mild cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. NeuroImage. Clinical 2018-07-23 Brain scans and imaging

    Locus of control (LOC) is an important personality trait.

  17. Insomnia and Mild Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Gerontology & geriatric medicine 2018-06-01 Risk factors

    Insomnia is a common problem in older people, especially in patients with mild cognitive impairment (MCI) whose circadian rhythm is often compromised.

  18. Age-Related Hearing Loss: Innovations in Hearing Augmentation

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Otolaryngologic clinics of North America 2018-05-04 Risk factors

    Age-related hearing loss is a multifactorial condition that affects more than one-third of the aging population.

  19. Functional Disconnectivity during Inter-Task Resting State in Dementia with Lewy Bodies

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Dementia and geriatric cognitive disorders 2018-05-03 Brain scans and imaging

    While the DLB patients scored well and did not differ from the control and AD groups in terms of functional activity and connectivity during the task conditions, they showed decreased functional connectivity in visuoperceptual regions during the resting state condition, along with a temporal impairment of the default-mode network activity.

  20. Education amplifies brain atrophy effect on cognitive decline: implications for cognitive reserve

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Neurobiology of aging 2018-04-12 Risk factors

    Level of education is often regarded as a proxy for cognitive reserve in older adults.

  21. Neuropsychological differentiation of progressive aphasic disorders

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Journal of neuropsychology 2018-02-08 Prevention trials

    The differentiation of subtypes of primary progressive aphasia (PPA) remains challenging.

  22. Vision in Alzheimer's disease: a focus on the anterior afferent pathway

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Neurodegenerative disease management 2018-01-23 Brain scans and imaging

    Visual dysfunction has long been recognized as a manifestation of Alzheimer's disease (AD), particularly in the form of visuospatial impairment during all stages of disease.

  23. Default Mode Network Lateralization and Memory in Healthy Aging and Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Journal of Alzheimer's disease : JAD 2018 Brain scans and imaging

    Lateralization of default mode network (DMN) functioning has been shown to change with age.

  24. [Sleep and wakefulness disorders in neurodegenerative diseases]

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 2018 Risk factors

    The article reviews the phenomenology of sleep and wakefulness disorders in Parkinson's disease and Alzheimer's disease.

  25. Late-life Depression and Alzheimer Disease: A Potential Synergy of the Underlying Mechanisms

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Current medicinal chemistry 2018 Risk factors

    A number of biological and clinical characteristics typical of late life depression (LLD) have been suggested by recent research findings.

From across this topic

10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

Other topics