Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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This study used measured data from 108 participants and the synthesized data generated from the measured data.
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A total of 124 participants with Alzheimer disease, cerebrovascular disease, or a mix Alzheimer's and cerebrovascular diseases and 55 controlparticipants underwent magnetic resonance imaging and neuropsychological testing.
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Analysis showed strong correlation between (1) XpressO memory tasks scores and the MoCA Memory Index Score (p-values < 0.001), and between (2) XpressO sub-test scores and MoCA total score (p-values < 0.005).
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Hypertension is associated with impaired cognition, and when combined with MCI, it may lead to a poor prognosis.
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Education partially mediated the effect of adolescent cognition on CI in the cognitive assessment aample and AD8 in the questionnaire sample (Ps < 0.001).
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A total of 406 FHS (Framingham Heart Study) and 59 BHS (Bogalusa Heart Study) participants with traditional neuropsychological tests and digital assessments using the Defense Automated Neurocognitive Assessment (DANA) smartphone protocol were included.
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166 patients were consecutively enrolled (mean age was 85.7 years old, females composed 68%); 25% had a diagnosis of amnestic mild cognitive impairment, and 75% had a diagnosis of dementia.
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Of 101 participants, 85 older adults without dementia (84.1%) who completed the study protocol were included in the statistical analysis.
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52/100
Pupillometry is a measurement of pupil dilation commonly performed as part of neurological assessments.
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These preliminary findings suggest that derived digital biomarkers may identify cognitive impairment in preclinical and prodromal AD, and may predict disease progression.
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Polynomial regressions indicated an 0.23 kg/m2 decrease in BMI per year beginning at age 36.5 years, which occurs alongside the period during which Aβ and tau increase and memory and mental status decline.
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When considering race/ethnicity, the presence of more vascular comorbidities drove greater vulnerability.
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The paper aimed to compare how factors previously identified as predictive factors for cognitive decline and dementia related to cognitive performance on the one hand and brain health on the other.
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The pattern of deficits across tasks was qualitatively compared with normal age-related decline, and early-stage dementia.
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Frontotemporal dementia associated with granulin (GRN) mutations presents asymmetric brain atrophy.
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Differences in expressing facial emotions are broadly observed in people with cognitive impairment.
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Late-life depression (LLD) increases risk for dementia and brain pathology, but possibly this is only true for one or more symptom profiles of LLD.
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This narrative review aimed to explore the existing knowledge in order to examine the multiple forms of late-life depression (LLD) within a non-neurodegenerative or a neurodegenerative context, in particular Alzheimer's disease (AD).
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RECENT FINDINGS: MetS was associated with lower domain-specific and global cognitive function in most cross-sectional studies, but findings from longitudinal studies are not consistent.
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Baseline depression and low cognitive reserve significantly increased the risk of subsequent dementia at follow-up.
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52/100
Cognitive resilience is an important modulating factor of cognitive decline in Alzheimer's disease, but the functional brain mechanisms that support cognitive resilience remain elusive.
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The ICA demonstrated convergent validity with MoCA (Pearson r=0.58, p<0.0001) and ACE (r=0.62, p<0.0001).
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Our study is well placed to evaluate the clinical utility of RMT assessments.
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Variability in step velocity and cadence had the highest predictive utility in identifying individuals with mild AD.
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Previous studies have shown that the diagnostic performance of digital cognitive tests is comparable with that of conventional paper-and-pencil tests.
From across this topic
10 of the 1,533 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Gender bias in the diagnosis of Alzheimer's Disease
- Effectiveness of Modern Diagnostic and Therapeutic Interventions for Major Neurological Disorders: A Systematic Literature Review
- Retinal thickness in Alzheimer's disease: A systematic review and meta-analysis
- Atrophy of presubiculum and subiculum is the earliest hippocampal anatomical marker of Alzheimer's disease
- Hearing impairment and cognitive decline in senile dementia of the Alzheimer's type
- Brain Network Connectivity Mediates Education-related Cognitive Performance in Healthy Elderly Adults
- Intrinsic functional connectivity, CSF biomarker profiles and their relation to cognitive function in mild cognitive impairment
- Doctor, Should I Use Computer Games to Prevent Dementia?
- A Novel Imaging Marker for Small Vessel Disease Based on Skeletonization of White Matter Tracts and Diffusion Histograms
- Forecasting Alzheimer’s disease progression using non-imaging clinical features and XGBoost