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General cognitive ability in high school, attained education, occupational complexity, and dementia risk
Jimi Huh, Thalida Em Arpawong, Tara L Gruenewald, Gwenith G Fisher, Carol A Prescott, Jennifer J Manly, Dominika Seblova, Ellen E Walters et al.. Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024-02-20
Topic: Brain imaging, connectivity and assessment
Education partially mediated the effect of adolescent cognition on CI in the cognitive assessment aample and AD8 in the questionnaire sample (Ps < 0.001). Within twin pairs, differences in adolescent cognition were small, but intrapair differences in education predicted CI status. Adolescent cognition predicted dementia risk 60 years later, partially mediated through education. Educational attainment, but not occupational complexity, contributes to CI risk beyond its role as a mediator of adolescent cognition, further supported by the co-twin analyses. HIGHLIGHTS: Project Talent Aging Study follows enrollees from high school for nearly 60 years. General cognitive ability in high school predicts later-life cognitive impairment. Low education is a risk partially due to its association with cognitive ability.
Key findings
- Education partially mediated the effect of adolescent cognition on CI in the cognitive assessment aample and AD8 in the questionnaire sample (Ps < 0.001).
- Within twin pairs, differences in adolescent cognition were small, but intrapair differences in education predicted CI status.
- Adolescent cognition predicted dementia risk 60 years later, partially mediated through education.
- Educational attainment, but not occupational complexity, contributes to CI risk beyond its role as a mediator of adolescent cognition, further supported by the co-twin analyses.
- HIGHLIGHTS: Project Talent Aging Study follows enrollees from high school for nearly 60 years.
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Study details
- Evidence strengthLow
How this study scored 52/100
Published in a leading specialty journal. Scored zero for study design, sample size, effect reported and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multi-centre collaboration and free to read, so those were left out: it earned 29 of the 56 points we could judge it on, which is 52 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (Alzheimer's & dementia : the journal of the Alzheimer's Association) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2024 — within 3 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (pubmed indexes it as a clinical or observational study) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 38375960) |
| Free to read | — / 2 | Access not recorded — left out of this score |
| Points | 29 / 56 | Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 29 of the 56 points we could judge it on is 52 out of 100. |
| Total | 52 / 100 | — |
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APA 7th
Huh, J., Arpawong, T. E., Gruenewald, T. L., Fisher, G. G., Prescott, C. A., Manly, J. J., et al. (2024). General cognitive ability in high school, attained education, occupational complexity, and dementia risk. Alzheimer's & dementia : the journal of the Alzheimer's Association. https://doi.org/10.1002/alz.13739
Vancouver
Huh J, Arpawong TE, Gruenewald TL, Fisher GG, Prescott CA, Manly JJ, et al. General cognitive ability in high school, attained education, occupational complexity, and dementia risk. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024. doi:10.1002/alz.13739. PMID: 38375960.
BibTeX
@article{huh2024-38375960,
author = {Huh, Jimi and Arpawong, Thalida Em and Gruenewald, Tara L and Fisher, Gwenith G and Prescott, Carol A and Manly, Jennifer J and Seblova, Dominika and Walters, Ellen E and others},
title = {{General cognitive ability in high school, attained education, occupational complexity, and dementia risk}},
journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
year = {2024},
doi = {10.1002/alz.13739},
pmid = {38375960},
url = {https://doi.org/10.1002/alz.13739}
}