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Increased risk of dementia in patients with mild traumatic brain injury: a nationwide cohort study
Lee YK, Hou SW, Lee CC, Hsu CY, Huang YS, Su YC.. PloS one, 2013-05-01
Topic: Risk, prevention and care in population studies
Background It is known that the risk of dementia in patients with moderate to severe traumatic brain injury (TBI) is higher. However, the relationship between mild traumatic brain injury (mTBI) and dementia has never been established. Objectives We investigated the incidences of dementia among patients with mTBI in Taiwan to evaluate if there is higher risk compared with general population. Methods We utilized a sampled National Health Insurance (NHI) claims data containing one million beneficiaries. We followed all adult beneficiaries from January 1, 2005 till December 31, 2009 to see if they had been diagnosed with dementia. We further identify patients with mTBI and compared their risk of dementia with the general population. Results We identified 28551 patients with mTBI and 692382 without. After controlled for age, gender, urbanization level, socioeconomic status, diabetes, hypertension, coronary artery disease, hyperlipidemia, history of alcohol intoxication, history of ischemic stroke, history of intracranial hemorrhage and Charlson Comorbidity Index Score, the adjusted hazard ratio is 3.26 (95% Confidence interval, 2.69-3.94). Conclusions TBI is an independent significant risk factor of developing dementia even in the mild type.
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APA 7th
Lee, Y. K., Hou, S. W., Lee, C. C., Hsu, C. Y., Huang, Y. S., & Su, Y. C. (2013). Increased risk of dementia in patients with mild traumatic brain injury: a nationwide cohort study. PloS one. https://doi.org/10.1371/journal.pone.0062422
Vancouver
Lee YK, Hou SW, Lee CC, Hsu CY, Huang YS, Su YC. Increased risk of dementia in patients with mild traumatic brain injury: a nationwide cohort study. PloS one. 2013. doi:10.1371/journal.pone.0062422. PMID: 23658727.
BibTeX
@article{lee2013-23658727,
author = {Lee, Y. K. and Hou, S. W. and Lee, C. C. and Hsu, C. Y. and Huang, Y. S. and Su, Y. C.},
title = {{Increased risk of dementia in patients with mild traumatic brain injury: a nationwide cohort study}},
journal = {PloS one},
year = {2013},
doi = {10.1371/journal.pone.0062422},
pmid = {23658727},
url = {https://doi.org/10.1371/journal.pone.0062422}
}
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Key findings
- Objectives We investigated the incidences of dementia among patients with mTBI in Taiwan to evaluate if there is higher risk compared with general population.
- Results We identified 28551 patients with mTBI and 692382 without.
- Conclusions TBI is an independent significant risk factor of developing dementia even in the mild type.
Study details
- Participants28,551
- Evidence strengthLow
How this study scored 52/100
Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomized / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record and multicenter collaboration, so those were left out: it earned 30 of the 58 points we could judge it on, which is 52 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (PloS one) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2013 — within 20 year(s) of the newest study here |
| Sample size | 4 / 4 | 28,551 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomized / blinded | 0 / 2 | No randomization or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multicenter collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 23658727) |
| Free to read | 2 / 2 | Free to read |
| Points | 30 / 58 | Scored on 11 of 20 parts. We have no data for the rest, so they are left out: 30 of the 58 points we could judge it on is 52 out of 100. |
| Total | 52 / 100 | — |
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