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Summary of the best evidence for non-pharmaceutical interventions for mild cognitive impairment in Parkinson’s disease
Yud Dan Liu, Huizhong Li, Yu Zhai, Yu Ling Shen, Jinmei Yang, Li He, Ting Shen. Frontiers in Neurology, 2025-07-03
Topic: Risk, prevention and care in population studies
Thirteen studies were included (five guidelines, two clinical decisions, two systematic reviews, one meta-analysis, and three RCTs). Twenty evidence points were categorized into six themes: safety/efficacy, assessment, cognitive training, exercise, health education, and multi-strategy approaches. This study consolidates evidence supporting non-pharmacological interventions for PD-MCI, offering actionable recommendations for clinical practice to delay progression to Parkinson's disease dementia (PDD).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Liu, Y. D., Li, H., Zhai, Y., Shen, Y. L., Yang, J., He, L., et al. (2025). Summary of the best evidence for non-pharmaceutical interventions for mild cognitive impairment in Parkinson’s disease. Frontiers in Neurology. https://doi.org/10.3389/fneur.2025.1598974
Vancouver
Liu YD, Li H, Zhai Y, Shen YL, Yang J, He L, et al. Summary of the best evidence for non-pharmaceutical interventions for mild cognitive impairment in Parkinson’s disease. Frontiers in Neurology. 2025. doi:10.3389/fneur.2025.1598974. PMID: 40677685.
BibTeX
@article{liu2025-40677685,
author = {Liu, Yud Dan and Li, Huizhong and Zhai, Yu and Shen, Yu Ling and Yang, Jinmei and He, Li and Shen, Ting},
title = {{Summary of the best evidence for non-pharmaceutical interventions for mild cognitive impairment in Parkinson’s disease}},
journal = {Frontiers in Neurology},
year = {2025},
doi = {10.3389/fneur.2025.1598974},
pmid = {40677685},
url = {https://doi.org/10.3389/fneur.2025.1598974}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
Key findings
- Thirteen studies were included (five guidelines, two clinical decisions, two systematic reviews, one meta-analysis, and three RCTs).
- Twenty evidence points were categorized into six themes: safety/efficacy, assessment, cognitive training, exercise, health education, and multi-strategy approaches.
- This study consolidates evidence supporting non-pharmacological interventions for PD-MCI, offering actionable recommendations for clinical practice to delay progression to Parkinson's disease dementia (PDD).
Why it matters
This review of thirteen studies found evidence supporting non-pharmacological interventions for mild cognitive impairment in Parkinson's disease, with recommendations intended to delay progression to Parkinson's disease dementia. It does not report a cure or a new drug, but consolidates existing evidence across themes such as cognitive training, exercise, and health education.
Study details
- Study designmeta-analysis
- Evidence strengthHigh
How this study scored 49/100
Published in a peer-reviewed journal, and it is a meta-analysis pooling many studies. Scored zero for sample size, effect reported and studied in people because the record does not state it. We have no data on senior author's track record, so that was left out: it earned 47 of the 96 points we could judge it on, which is 49 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Frontiers in Neurology) |
| Journal's citation record | 2 / 4 | Frontiers in Neurology: journal h-index 162 (OpenAlex, 2026-10-29) |
| Study design | 12 / 12 | A meta-analysis pooling many studies |
| Strength of evidence | 5 / 5 | Rated “high” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | A review of other studies — randomisation is not credited here |
| Times cited | 1 / 7 | Cited 1 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.3 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 1 / 6 | Cited 0.6× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 1 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | — / 4 | OpenAlex's profile for last-listed author Ting Shen holds only 3 work(s), too few to judge a track record — left out of this score |
| Institution's track record | 0 / 3 | Yunnan University of Traditional Chinese Medicine: institution h-index 102 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 40677685) |
| Free to read | 2 / 2 | Free to read |
| Points | 47 / 96 | Scored on 19 of 20 parts. We have no data for the rest, so they are left out: 47 of the 96 points we could judge it on is 49 out of 100. |
| Total | 49 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.3389/fneur.2025.1598974
- PubMed: 40677685
- Original source →
- Free full text: Frontiers in Neurology →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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