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Physical activity, falls, and dementia risk in adults aged ≥ 60: evidence from three cohorts
Juxiang Yang, Minheng Zhang, Miaomiao Hou, Hongwei Liu, Haixia Fan. International Journal of Behavioral Nutrition and Physical Activity, 2026-05-09
Topic: Risk, prevention and care in population studies
Over a median follow-up of 5.9-7.9 years, 3,492 dementia cases were identified. Falls were associated with a 70% higher risk of dementia (pooled HR = 1.70, 95% CI: 1.57-1.84). In the no-fall group, compared with inactivity, low, moderate, and high physical activity were progressively associated with lower risks of dementia (HRs = 0.63, 0.53, 0.43) and falls (HRs = 0.77, 0.68, 0.58). These protective effects were consistent among fallers, with similar dose-response gradients. Falls substantially increased dementia risk. Higher levels of physical activity were linked to lower risks of both dementia and falls, regardless of fall history.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Yang, J., Zhang, M., Hou, M., Liu, H., & Fan, H. (2026). Physical activity, falls, and dementia risk in adults aged ≥ 60: evidence from three cohorts. International Journal of Behavioral Nutrition and Physical Activity. https://doi.org/10.1186/s12966-026-01926-9
Vancouver
Yang J, Zhang M, Hou M, Liu H, Fan H. Physical activity, falls, and dementia risk in adults aged ≥ 60: evidence from three cohorts. International Journal of Behavioral Nutrition and Physical Activity. 2026. doi:10.1186/s12966-026-01926-9. PMID: 42106826.
BibTeX
@article{yang2026-42106826,
author = {Yang, Juxiang and Zhang, Minheng and Hou, Miaomiao and Liu, Hongwei and Fan, Haixia},
title = {{Physical activity, falls, and dementia risk in adults aged ≥ 60: evidence from three cohorts}},
journal = {International Journal of Behavioral Nutrition and Physical Activity},
year = {2026},
doi = {10.1186/s12966-026-01926-9},
pmid = {42106826},
url = {https://doi.org/10.1186/s12966-026-01926-9}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
Key findings
- Over a median follow-up of 5.9-7.9 years, 3,492 dementia cases were identified.
- Falls were associated with a 70% higher risk of dementia (pooled HR = 1.70, 95% CI: 1.57-1.84).
- In the no-fall group, compared with inactivity, low, moderate, and high physical activity were progressively associated with lower risks of dementia (HRs = 0.63, 0.53, 0.43) and falls (HRs = 0.77, 0.68, 0.58).
- These protective effects were consistent among fallers, with similar dose-response gradients.
- Falls substantially increased dementia risk.
Why it matters
Across three cohorts, falls were linked to a 70% higher risk of dementia, and higher physical activity was linked to lower risks of both dementia and falls. These are observational associations, so they cannot prove that activity prevents dementia.
Study details
- Participants44,488
- Effect sizeHR = 1.70
- Evidence strengthLow
How this study scored 46/100
Published in a peer-reviewed journal. Scored zero for study design and randomized / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (International Journal of Behavioral Nutrition and Physical Activity) |
| Journal's citation record | 2 / 4 | International Journal of Behavioral Nutrition and Physical Activity: journal h-index 208 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 5 / 5 | 2026 — within 1 year(s) of the newest study here |
| Sample size | 4 / 4 | 44,488 participants |
| Effect reported | 3 / 3 | Effect reported with a statistic (interval, p-value, ratio or similar) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomized / blinded | 0 / 2 | No randomization or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 1 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.5 citations a year over 2 year(s) since 2026 |
| Impact for its field and year | 3 / 6 | Cited 4.7× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 1 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 1 / 4 | Last-listed author Haixia Fan: h-index 5 (OpenAlex, whole career) |
| Institution's track record | 0 / 3 | Capital Medical University: institution h-index 643 (OpenAlex) |
| Multicenter collaboration | 2 / 3 | OpenAlex lists 6 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 42106826) |
| Free to read | 2 / 2 | Free to read |
| Total | 46 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1186/s12966-026-01926-9
- PubMed: 42106826
- Original source →
- Free full text: International Journal of Behavioral Nutrition and Physical Activity →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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