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64/100

✓ Peer-reviewed alzhub usefulness score 64 out of 100. Vascular contributions

Topic: Brain proteins, microglia and lab models

An international working group from the Centres of Excellence in Neurodegeneration completed a structured process to develop definitions and imaging standards for markers and consequences of cerebral small vessel disease (SVD). The study aimed to provide a common advisory about terms and definitions for MRI features, suggest minimum standards for image acquisition and analysis, agree on scientific reporting standards, and review emerging imaging methods for detection and quantification of preclinical manifestations of SVD. The position paper summarizes the outcomes of this effort to provide the STandards for ReportIng Vascular changes on nEuroimaging (STRIVE), which can be used in research studies and clinical settings.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Wardlaw, J. M., Smith, E. E., Biessels, G. J., Cordonnier, C., Fazekas, F., Frayne, R., et al. (2013). Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. The Lancet Neurology. https://doi.org/10.1016/s1474-4422(13)70124-8

Vancouver

Wardlaw JM, Smith EE, Biessels GJ, Cordonnier C, Fazekas F, Frayne R, et al. Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. The Lancet Neurology. 2013. doi:10.1016/s1474-4422(13)70124-8. PMID: 23867200.

BibTeX

@article{wardlaw2013-23867200,
  author  = {Wardlaw, Joanna Marguerite and Smith, Eric Edward and Biessels, Geert Jan and Cordonnier, Charlotte and Fazekas, Franz and Frayne, Richard and Lindley, Richard I. and O'Brien, John Tiernan and others},
  title   = {{Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration}},
  journal = {The Lancet Neurology},
  year    = {2013},
  doi     = {10.1016/s1474-4422(13)70124-8},
  pmid    = {23867200},
  url     = {https://doi.org/10.1016/s1474-4422(13)70124-8}
}

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Key findings

We completed a structured process to develop definitions and imaging standards for markers and consequences of SVD.
Our findings and recommendations apply to research studies, and can be used in the clinical setting to standardise image interpretation, acquisition, and reporting.
This Position Paper summarises the main outcomes of this international effort to provide the STandards for ReportIng Vascular changes on nEuroimaging (STRIVE).

Why it matters

Sets out neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Shared standards make imaging studies comparable with one another; they do not themselves treat or prevent disease.

Study details

Evidence strengthLow

How this study scored 64/100

Published in a leading specialty journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it.

Component	Points	Why
Journal tier	9 / 10	Tier 2 — leading specialty journal (The Lancet Neurology)
Journal's citation record	3 / 4	The Lancet Neurology: journal h-index 457 (OpenAlex, 2026-10-29)
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	1 / 5	2013 — within 20 year(s) of the newest study here
Sample size	0 / 4	Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	0 / 3	Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomised / blinded	0 / 2	No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	7 / 7	Cited 5,426 times (OpenAlex, 2026-10-10)
Citations per year	5 / 5	361.7 citations a year over 15 year(s) since 2013
Impact for its field and year	6 / 6	Cited 106.8× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	5 / 6	Cited by 129 other studies in this library
Still being cited	4 / 4	Cited 1,496 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	4 / 4	Last-listed author Martin Dichgans: h-index 146 (OpenAlex, whole career)
Institution's track record	2 / 3	Massachusetts General Hospital: institution h-index 2,057 (OpenAlex)
Multi-centre collaboration	3 / 3	OpenAlex lists 40 institution(s) in 13 countries
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 23867200)
Free to read	2 / 2	Free to read
Total	64 / 100	—

What each of these 20 components measures, and what this score is not →

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