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reserve
208 studies tagged reserve, dated 1979-11-01 to 2026-11-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment 2026-11-01
- Cognition in healthy aging, ages 36 to 108: Associations with dementia risk factors and neurodegenerative disease biomarkers 2026-10-28
- Geographic Heterogeneity in the Association Between Schooling and Cognitive Change Among Older Adults in India 2026-10-28
Studies
208 studies carry this tag.
Date range
1979 to 2026
Top journals
- Alzheimer's & dementia : the journal of the Alzheimer's Association 14
- Research Square 14
- Neurobiology of aging 10
- Journal of Alzheimer's disease : JAD 9
- Alzheimer's & dementia (Amsterdam, Netherlands) 7
107 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Among 10,489 participants with incident MCI, the mean age at the incident MCI wave was 70.6 years (SD = 11.53), and 56.6% were female.
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Most evidence on dementia risk factors comes from older or clinical samples, leaving their relation to normal cognitive aging unclear.
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Higher educational attainment is associated with steeper measured cognitive decline among older adults in India, but whether this association is uniform across the country is unknown.
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Dementia is a progressive syndrome characterized by neurodegeneration across distributed brain networks that results in cognitive, behavioral, and functional declines.
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Parental history of dementia is a risk factor for Alzheimer’s disease, although the mechanisms underlying this association remain poorly understood.
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Key Points Question Which candidate plasma proteins are associated with cognitive performance across multiple domains in older adults from the Democratic Republic of Congo?
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This nationwide study provides epidemiological data on dementia and MCI among adults aged ≥ 60 years across all 12 administrative regions of Morocco.
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The social, structural, and physical conditions in which individuals live, work, and age, collectively termed social determinants of health (SDOH), are associated with risk of Alzheimer's disease and related dementias (ADRD).
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Memory IIV may be more closely linked to hippocampal white matter, while mean memory performance may better reflect hippocampal volume.
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Among 1,231 patients (87.2% women; mean age 46.0 ± 13.7 years; 71.5% chronic migraine), 1,175/1,231 (95.5%) endorsed cognitive symptoms, with a mean Mig-SCog total score of 8.2 ± 4.8.
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Among individuals with mild cognitive impairment, no vision impairment (VI) and corrected VI were associated with a lower risk of dementia than uncorrected VI, particularly among those aged < 75 years.
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Greater diversity of social participation was associated with better long-term cognitive maintenance among older adults with hypertension and/or diabetes.
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Mean age was 59.6 years, and 57.8% were male.
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Prior work has demonstrated a link between cognitive impairment and financial vulnerability.
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This study aimed to address these limitations by examining whether multilingual experience is associated with longitudinal ageing trajectories across objective and subjective measures spanning cognitive, affective, linguistic, and non-linguistic domains.
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Aging is characterized by normative changes in memory and a continued capacity for goal-directed learning and adaptation.
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The conventional model (M2) concordance index (C-index) was 0.680, but fell to 0.649 when missingness indicators were removed.
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CAD was not associated with global or domain-level neurocognitive performance.
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In this cross-sectional sample, mobility showed a progressively stronger statistical indirect association with the cognition-ADL relationship as cognitive impairment deepened.
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M2 C-index 0.682, M3 0.692, M4 0.687. Adding the dyadic mean yielded an estimated ΔC of 0.010 (95% CI -0.003 to 0.024).
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Natural language processing has been examined as a possible biomarker for cognitive decline and dementia, but it has also been associated with components of well-being and psychological distress.
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We compared global and domain-level cognitive performance in older adults without a prior dementia diagnosis based on whether their cohabiting spouse had Alzheimer’s disease.
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ObjectivesIdentifying modifiable factors that shape cognitive aging trajectories is a central goal in aging research.
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In dialect-dominant, educationally diverse elderly, Mini-cog provides superior diagnostic accuracy for MCI versus HKBC and MoCA, and comparable accuracy for dementia.
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Population ageing is accelerating globally, with a rising burden of neurocognitive disorders such as dementia and Alzheimer’s disease, particularly in low- and middle-income countries.
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Middle-aged adults with faster 15-year epigenetic aging trajectories demonstrated worse cognitive performance, whereas those with slower biological aging trajectories exhibited cognitive resilience and more favorable AD biomarker profiles.
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Individuals with cognitive profiles consistent with probable executive MCI were identified using simple assessments of global cognition, memory and executive functions in a community-dwelling older population.
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16/100
Older age was associated with lower Att-Z (β = −0.315, p < 0.001).
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All Big Five domains had prospective associations with multiple dementia risk factors and with cognitive impairment, cognitive function, and self-reported memory.
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Adding MDLC to p-tau217 significantly explained longitudinal cognitive trajectory beyond p-tau217 alone.
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Survivors of childhood cancer are prone to neurocognitive impairment and premature aging, raising concerns about early onset dementia.
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aECAD was associated with significantly worse scores in processing speed (β = -0.19, p = 0.004) and executive function (β = -0.20, p = 0.009) domains after controlling for age, sex, education, race, and ethnicity.
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Trajectories of systolic BP were separated markedly around 25 to 45 years of age, with the group below the median of cognition score having higher levels of systolic BP than the group above the median.
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By incorporating sex, place of residence, age, and years of education as covariates, the TabCAT-BHA demonstrated greater accuracy in detecting cognitive impairment (AUC = 75.3%) compared to the MMSE (AUC = 66.4%) and RUDAS (AUC = 71.4%).
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Cognitive reserve and frailty are factors associated with Alzheimer's disease and related dementias (ADRD).
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46/100
Although modifiable risk factors may account for around 40 % of population variability in dementia risk, the effect of risk factor interrelationships on pathology-cognition relationships is poorly understood.
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With aging, the hippocampal formation shows variable structural atrophy, which is associated with a decline in cognitive performance.
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A+/High-EA individuals exhibited slower cognitive decline in global cognition and language domains than A+/Low-EA individuals.
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Participants with faster DunedinPACE had poorer cognitive functioning at baseline and experienced more rapid cognitive decline over follow-up.
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As the literature related to cognitive reserve (CR) in individuals with frontotemporal dementia (FTD) is only emerging, a clear consensus on the relationship among CR proxies, brain status, and clinical performance has not been reached.
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No significant association was found between social isolation and ToM abilities for both the unadjusted and adjusted models.
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Significant interactions were found between APOE ε4 status and mindfulness and social engagement on cognitive reserve, indicating stronger associations for APOE ε4 carriers.
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Greater educational attainment and mental activity were associated with higher composite SPPB scores and those of its three subtests (p < 0.05).
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Associations between epigenetic AA and cognitive performance over-time varied by sex.
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In the low-education group, low literacy, long sleep duration(>8 h/day), and diabetes were negatively associated with CR, whereas cognitive and physical activity were positively associated with CR.
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In weighted models, greater loneliness was associated with microinfarcts, lower episodic and working memory in the absence of AD pathology, lower working memory in the absence of infarcts, a stronger association of infarcts with lower episodic memory, and a stronger association of microinfarcts with lower working and semantic memory.
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Among the cohort of 7180 older adults (median age, 74 years [range, 65-102 years]; 4729 women [65.9%]), 1036 were African American or Black (14.4%), 21 were American Indian or Alaska Native (0.3%), 143 were Asian (2.0%), 332 were Hispanic (4.6%), and 5648 were non-Hispanic White (78.7%); the median educational level was 16.0 years (range, 1.0-29.0 years).
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Higher CRI scores were associated with better cognition.
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54/100
We tested if cognitive and brain reserve and maintenance explain individual differences in episodic memory and other cognitive domains from late middle to early older adulthood.
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55/100
We evaluate-also in a critical way-the methods commonly used to define and measure CR, including sociobehavioral proxies, neuroimaging, and electrophysiological and genetic measures.
From across this tag
8 of the 208 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 8. The same 8 appear here every time.
- Right hemisphere role in cognitive reserve
- Childhood socioeconomic position and cognitive function in adulthood
- Baseline neuropsychiatric symptoms and the risk of incident mild cognitive impairment: a population-based study
- Cognitive activity, education and socioeconomic status as preventive factors for mild cognitive impairment and Alzheimer's disease
- Are Brain and Cognitive Reserve Shaped by Early Life Circumstances?
- Cognitive and behavioural flexibility: neural mechanisms and clinical considerations
- Association of premorbid intellectual function with cerebral metabolism in Alzheimer's disease: implications for the cognitive reserve hypothesis
- Tipping the Balance Between Cognitive Reserve, Frailty, and Dementia in the Very Old?