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Assessment of Cognitive Functions in Multimorbid Patients in Lithuanian Primary Care Settings: A Cross-Sectional Study Using MMSE and LT-GPCOG
Silvija Valdonė Alšauskė, Ingrida Grabauskytė, Ida Liseckienė, Jūratė Macijauskienė. Medicina, 2025-01-14
Topic: Risk, prevention and care in population studies
Out of 796 participants, 793 completed the study. Cognitive impairment was suspected in 5.1% of participants based on MMSE and 4.2% based on the LT-GPCOG. Statistically significant associations were found between cognitive impairment and chronic obstructive pulmonary disease (COPD) (p = 0.008 and p = 0.003) in both tests and chronic kidney disease (CKD) (p = 0.005) while testing with the MMSE. Lower education and unemployment were also correlated with cognitive impairment (p = 0.008 and p < 0.001). The findings suggest that regular cognitive assessments should be integrated into the management of multimorbid patients, particularly those with COPD and CKD. The LT-GPCOG proved to be an efficient alternative to the MMSE in primary care settings, demonstrating comparable diagnostic accuracy. Further studies are also needed to assess the sensitivity and specificity of the LT-GPCOG test.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Alšauskė, S. V., Grabauskytė, I., Liseckienė, I., & Macijauskienė, J. (2025). Assessment of Cognitive Functions in Multimorbid Patients in Lithuanian Primary Care Settings: A Cross-Sectional Study Using MMSE and LT-GPCOG. Medicina. https://doi.org/10.3390/medicina61010122
Vancouver
Alšauskė SV, Grabauskytė I, Liseckienė I, Macijauskienė J. Assessment of Cognitive Functions in Multimorbid Patients in Lithuanian Primary Care Settings: A Cross-Sectional Study Using MMSE and LT-GPCOG. Medicina. 2025. doi:10.3390/medicina61010122. PMID: 39859104.
BibTeX
@article{alsauske2025-39859104,
author = {Alšauskė, Silvija Valdonė and Grabauskytė, Ingrida and Liseckienė, Ida and Macijauskienė, Jūratė},
title = {{Assessment of Cognitive Functions in Multimorbid Patients in Lithuanian Primary Care Settings: A Cross-Sectional Study Using MMSE and LT-GPCOG}},
journal = {Medicina},
year = {2025},
doi = {10.3390/medicina61010122},
pmid = {39859104},
url = {https://doi.org/10.3390/medicina61010122}
}
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Key findings
- Out of 796 participants, 793 completed the study.
- Cognitive impairment was suspected in 5.1% of participants based on MMSE and 4.2% based on the LT-GPCOG.
- Statistically significant associations were found between cognitive impairment and chronic obstructive pulmonary disease (COPD) (p = 0.008 and p = 0.003) in both tests and chronic kidney disease (CKD) (p = 0.005) while testing with the MMSE.
- Lower education and unemployment were also correlated with cognitive impairment (p = 0.008 and p < 0.001).
- The findings suggest that regular cognitive assessments should be integrated into the management of multimorbid patients, particularly those with COPD and CKD.
Why it matters
Among 793 multimorbid primary care patients in Lithuania, cognitive impairment was suspected in 5.1% by MMSE and 4.2% by LT-GPCOG, and was significantly associated with COPD and CKD as well as lower education and unemployment. The authors suggest regular cognitive assessments for multimorbid patients and say the LT-GPCOG was comparable to the MMSE, but this is about screening, not treatment, cure, or prevention.
Study details
- Study designcross-sectional
- Participants796
- Effect size5.1%; 4.2%
- Evidence strengthLow
How this study scored 44/100
Published in a peer-reviewed journal, and it is a snapshot of people at one point in time. Scored zero for randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Medicina) |
| Journal's citation record | 1 / 4 | Medicina: journal h-index 107 (OpenAlex, 2026-10-29) |
| Study design | 4 / 12 | A snapshot of people at one point in time |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 2 / 4 | 796 participants |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 2 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.7 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 2 / 6 | Cited 1.3× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 1 / 6 | Cited by 1 other studies in this library |
| Still being cited | 0 / 4 | Cited 2 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 1 / 4 | Last-listed author Jūratė Macijauskienė: h-index 19 (OpenAlex, whole career) |
| Institution's track record | 0 / 3 | Lithuanian University of Health Sciences: institution h-index 293 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 39859104) |
| Free to read | 2 / 2 | Free to read |
| Total | 44 / 100 | — |
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