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Newest in this topic

  1. From group-level neurophysiological biomarkers to individual-level phenotyping to identify mechanisms of neurodegenerative disease 2026-10-28
  2. Beyond reduced alpha power: a weaker temporal link between alpha and other brain rhythms in Alzheimer’s disease 2026-10-26
  3. Network Localization of Anxiety as an Early Manifestation of Alzheimer’s Disease-related Neurodegeneration 2026-10-26

Studies

187 studies carry this tag.

Date range

1998 to 2026

Top journals

  • Frontiers in aging neuroscience 10
  • bioRxiv 10
  • Brain : a journal of neurology 9
  • Human brain mapping 7
  • Journal of Alzheimer's disease : JAD 7

88 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Functional Connectivity of the Hippocampus in Early- and vs. Late-Onset Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Journal of clinical neurology (Seoul, Korea) 2017-10 Brain scans and imaging

    The functional connectivity from the hippocampus to other brain regions differed between patients with EOAD and LOAD.

  2. Frequency-Dependent Altered Functional Connections of Default Mode Network in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Frontiers in aging neuroscience 2017-08-03 Brain scans and imaging

    Alzheimer's disease (AD) is a neurodegenerative disorder associated with the progressive dysfunction of cognitive ability.

  3. The anatomy of apathy: A neurocognitive framework for amotivated behaviour

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Neuropsychologia 2017-07-08 Clinical safety

    Apathy is a debilitating syndrome associated with many neurological disorders, including several common neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, and focal lesion syndromes such as stroke.

  4. Aberrant Intrinsic Activity and Connectivity in Cognitively Normal Parkinson's Disease

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Frontiers in aging neuroscience 2017-06-19 Brain scans and imaging

    The results revealed abnormally increased and decreased ALFF and ReHo in PD-CN patients within the default mode network (posterior cingulate, inferior parietal cortex, parahippocampus, entorhinal cortex), sensorimotor cortex (primary motor, pre/post-central gyrus), basal ganglia (putamen, caudate), and posterior cerebellar lobule VII, which mediates cognition.

  5. Altered Functional Connectivity of Cognitive-Related Cerebellar Subregions in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Frontiers in aging neuroscience 2017-05-16 Brain scans and imaging

    Alzheimer's disease (AD) is the most common cause of dementia.

  6. Alzheimer's disease disrupts alpha and beta-band resting-state oscillatory network connectivity

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2017-05-08 Brain scans and imaging

    In bilateral parietotemporal areas, oscillatory envelope amplitude increased with healthy ageing, whereas both local amplitude and node-to-global connectivity decreased with AD.

  7. Resting-state network dysfunction in Alzheimer's disease: A systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 83 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2017-04-18 Brain scans and imaging

    Convergent evidence across the literature supports the use of resting-state connectivity as a biomarker of AD.

  8. Tau Pathology Distribution in Alzheimer's disease Corresponds Differentially to Cognition-Relevant Functional Brain Networks

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Frontiers in Neuroscience 2017-03-31 Brain scans and imaging

    Neuropathological studies have shown that the typical neurofibrillary pathology of hyperphosphorylated tau protein in Alzheimer’s disease (AD) preferentially affects specific brain regions whereas others remain relatively spared.

  9. Phases of Hyperconnectivity and Hypoconnectivity in the Default Mode and Salience Networks Track with Amyloid and Tau in Clinically Normal Individuals

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2017-03-17 Brain scans and imaging

    Alzheimer's disease (AD) is characterized by two hallmark molecular pathologies: amyloid aβ 1-42 and Tau neurofibrillary tangles.

  10. Systemic inflammation and resting state connectivity of the default mode network

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Brain, behavior, and immunity 2017-01-23 Brain scans and imaging

    The default mode network (DMN) encompasses brain systems that exhibit coherent neural activity at rest.

  11. Functional Disintegration of the Default Mode Network in Prodromal Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Journal of Alzheimer's disease : JAD 2017 Brain scans and imaging

    Neurodegenerative brain changes can affect the functional connectivity strength between nodes of the default-mode network (DMN), which may underlie changes in cognitive performance.

  12. Apathy and intrinsic functional connectivity networks in amnestic mild cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Neuropsychiatric disease and treatment 2016-12-23 Brain scans and imaging

    We observed that the FCs of the DMN were less and those of CEN were more in the aMCI group than the CON group.

  13. Network abnormalities and interneuron dysfunction in Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nature reviews. Neuroscience 2016-11-10 Brain scans and imaging

    The function of neural circuits and networks can be controlled, in part, by modulating the synchrony of their components' activities.

  14. Classification of patients with MCI and AD from healthy controls using directed graph measures of resting-state fMRI

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Behavioural brain research 2016-06-23 Digital health tools

    Brain network alterations in patients with Alzheimer's disease (AD) has been the subject of much investigation, but the biological mechanisms underlying these alterations remain poorly understood.

  15. Self, cortical midline structures and the resting state: Implications for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Neuroscience and biobehavioral reviews 2016-05-24 Brain scans and imaging

    Different aspects of the self have been reported to be affected in many neurological or psychiatric diseases such as Alzheimer's disease (AD), including mainly higher-level cognitive self-unawareness.

  16. A Multimodal Structural and Functional Neuroimaging Study of Amnestic Mild Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2016-05-04 Brain scans and imaging

    Examination of brain structural and functional abnormalities in amnestic mild cognitive impairment (aMCI) has the potential to enhance our understanding of the initial pathophysiological changes in dementia.

  17. Preclinical Cerebral Network Connectivity Evidence of Deficits in Mild White Matter Lesions

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Frontiers in aging neuroscience 2016-02-18 Brain scans and imaging

    White matter lesions (WMLs) are notable for their high prevalence and have been demonstrated to be a potential neuroimaging biomarker of early diagnosis of Alzheimer's disease.

  18. Metabolic connectomics targeting brain pathology in dementia with Lewy bodies

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2016-01-01 Brain tissue and pathology

    Dementia with Lewy bodies is characterized by α-synuclein accumulation and degeneration of dopaminergic and cholinergic pathways.

  19. Selectively Disrupted Functional Connectivity Networks in Type 2 Diabetes Mellitus

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Frontiers in aging neuroscience 2015-12-11 Brain scans and imaging

    We found that patients with T2DM exhibited cognitive function declines and functional connectivity disruptions within the default mode network, left frontal parietal network, and sensorimotor network.

  20. Cascading network failure across the Alzheimer's disease spectrum

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Brain : a journal of neurology 2015-11-19 Brain scans and imaging

    The two main findings of this paper are (i) the posterior default mode network fails before measurable amyloid plaques and appears to initiate a connectivity cascade that continues throughout the disease spectrum; and (ii) high connectivity between the posterior default mode network and hubs of high connectivity (many located in the frontal lobe) is associated with amyloid accumulation.

  21. Default mode network connectivity in patients with idiopathic normal pressure hydrocephalus

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of neurosurgery 2015-08-21 Brain scans and imaging

    Both ROI-based and voxel-based analyses revealed reduced DMN connectivity in patients with iNPH.

  22. Music, memory and mechanisms in Alzheimer’s disease: Figure 1

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Brain 2015-07-23 Treatments

    These same brain areas were then assessed in a cohort of patients with Alzheimer’s disease versus a healthy older reference group, using a region of interest approach combined with standard structural (MRI), metabolic (fluorodeoxyglucose-PET) and amyloid ligand (florbetapir-PET) neuroimaging.

  23. Altered cortical and subcortical local coherence in PTSD: evidence from resting-state fMRI

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Acta Radiologica 2015-06 Brain scans and imaging

    Compared with the normal controls, PTSD patients showed increased local coherence in subcortical regions, including amygdala, hippocampus, thalamus, and putamen, and decreased local coherence in cortical regions, including medial prefrontal cortex and dorsolateral prefrontal cortex.

  24. Aberrant functional connectivity of default-mode network in type 2 diabetes patients

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. European radiology 2015-04-23 Brain scans and imaging

    Patients showed increased connectivity around the medial prefrontal cortex in the anterior sub-network, but decreased connectivity around the posterior cingulate cortex in the posterior sub-network.

  25. Identifying patients with Alzheimer's disease using resting-state fMRI and graph theory

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2015-04-01 Digital health tools

    Classification based on the resting-state fMRI can be used as a non-invasive and automatic tool to diagnosis of Alzheimer's disease.

  26. Levels of Processing in Working Memory: Differential Involvement of Frontotemporal Networks

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Cognitive Neuroscience 2015-03-01 Lewy body dementia

    How does the brain maintain to-be-remembered information in working memory (WM), particularly when the focus of attention is drawn to processing other information?

  27. Chronology and Chronicity of Altered Resting-State Functional Connectivity after Traumatic Brain Injury

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Journal of Neurotrauma 2015-02 Brain scans and imaging

    Whereas traumatic brain injury (TBI) results in widespread disruption of neural networks, changes in regional resting-state functional connectivity patterns after insult remain unclear.

  28. Neuropsychiatric Symptoms and Functional Connectivity in Mild Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of Alzheimer's disease : JAD 2015 Brain scans and imaging

    There was a significant association between greater Affective factor symptoms and reduced FPCN connectivity (p = 0.03).

  29. Functional connectivity dynamics: modeling the switching behavior of the resting state

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. NeuroImage 2014-11-10 Brain scans and imaging

    Functional connectivity (FC) sheds light on the interactions between different brain regions.

  30. Resting-state networks link invasive and noninvasive brain stimulation across diverse psychiatric and neurological diseases

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2014-09-29 Brain scans and imaging

    Brain stimulation, a therapy increasingly used for neurological and psychiatric disease, traditionally is divided into invasive approaches, such as deep brain stimulation (DBS), and noninvasive approaches, such as transcranial magnetic stimulation.

  31. Structural and functional brain connectivity in presymptomatic familial frontotemporal dementia

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. Neurology 2014-07-08 Brain scans and imaging

    Carriers (n = 39) and noncarriers (n = 36) had similar neuropsychological performance, except for lower Letter Digit Substitution Test scores in carriers.

  32. The default mode network is disrupted in Parkinson's disease with visual hallucinations

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Human brain mapping 2014-07-01 Brain scans and imaging

    There were no group differences in cortical thickness but functional coactivation within components of the DMN was significantly lower in both PDVH and PDnonVH groups compared to HC.

  33. The hubs of the human connectome are generally implicated in the anatomy of brain disorders

    ✓ Peer-reviewed alzhub usefulness score 78 out of 100. Brain : a journal of neurology 2014-06-19 Brain scans and imaging

    Brain networks or 'connectomes' include a minority of highly connected hub nodes that are functionally valuable, because their topological centrality supports integrative processing and adaptive behaviours.

  34. Functional brain connectivity using fMRI in aging and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuropsychology review 2014-02-23 Brain scans and imaging

    Normal aging and Alzheimer's disease (AD) cause profound changes in the brain's structure and function.

  35. Working memory improvement with non-invasive brain stimulation of the dorsolateral prefrontal cortex: a systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Brain and cognition 2014-02-08 Risk factors

    Recent studies have used non-invasive brain stimulation (NIBS) techniques, such as repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), to increase dorsolateral prefrontal cortex (DLPFC) activity and, consequently, working memory (WM) performance.

  36. Network dysfunction in Alzheimer's disease and frontotemporal dementia: implications for psychiatry

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Biological psychiatry 2014-02-04 Brain scans and imaging

    Structural and functional connectivity methods are changing how researchers conceptualize and explore neuropsychiatric disease.

  37. Energetic cost of brain functional connectivity

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2013-07-29 Brain scans and imaging

    The brain's functional connectivity is complex, has high energetic cost, and requires efficient use of glucose, the brain's main energy source.

  38. Using resting state functional connectivity to unravel networks of tinnitus

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Hearing research 2013-07-26 Risk factors

    Resting state functional connectivity (rs-fc) using fMRI has become an important tool in examining differences in brain activity between patient and healthy populations.

  39. The role of the posterior cingulate cortex in cognition and disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Brain : a journal of neurology 2013-07-18 Brain scans and imaging

    However, other evidence suggests that the region is highly heterogeneous and may play a direct role in regulating the focus of attention.

  40. Aberrant functional organization within and between resting-state networks in AD

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. PloS one 2013-05-07 Brain scans and imaging

    Altered functional characteristics have been reported in amnestic mild cognitive impairment (aMCI) and Alzheimer's disease (AD); nonetheless, comprehensive analyses of the resting-state networks (RSNs) are rare.

  41. Resting state functional connectivity in preclinical Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Biological psychiatry 2013-01-04 Brain scans and imaging

    There has been a dramatic increase in the number of studies using resting state functional magnetic resonance imaging (rs-fMRI), a recent addition to imaging analysis techniques.

  42. Functional network connectivity in the behavioral variant of frontotemporal dementia

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2012-10-24 Brain scans and imaging

    A decreased dorsal salience network (DSN) connectivity, mainly involving the anterior cingulum, was observed in bvFTD versus controls and pAD.

  43. Abnormal network connectivity in frontotemporal dementia: evidence for prefrontal isolation

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2012-09-24 Digital health tools

    The present findings support a theory of FTD as a disorder of frontolimbic disconnection leading to unconstrained prefrontal connectivity.

  44. Non-stationarity in the "resting brain's" modular architecture

    ✓ Peer-reviewed alzhub usefulness score 76 out of 100. PloS one 2012-06-28 Brain scans and imaging

    Task-free functional magnetic resonance imaging (TF-fMRI) has great potential for advancing the understanding and treatment of neurologic illness.

  45. Disrupted functional brain connectome in individuals at risk for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Biological psychiatry 2012-04-25 Brain scans and imaging

    This study demonstrates a disruption of whole-brain topological organization of the functional connectome in aMCI.

  46. Resting-state fMRI as a biomarker for Alzheimer's disease?

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Alzheimer's research & therapy 2012-03-15 Brain scans and imaging

    Previous work indicates that resting-state functional magnetic resonance imaging (fMRI) is sensitive to functional brain changes related to Alzheimer's disease (AD) pathology across the clinical spectrum.

  47. Large-scale brain networks and psychopathology: a unifying triple network model

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Trends in cognitive sciences 2011-09-09 Risk factors

    The science of large-scale brain networks offers a powerful paradigm for investigating cognitive and affective dysfunction in psychiatric and neurological disorders.

  48. Resting-state fMRI changes in Alzheimer's disease and mild cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Neurobiology of aging 2011-08-20 Brain scans and imaging

    Regional functional connectivity (FC) of 39 patients with Alzheimer's disease (AD), 23 patients with mild cognitive impairment (MCI), and 43 healthy elderly controls was studied using resting-state functional magnetic resonance imaging (rs-fMRI).

  49. Functional connectivity tracks clinical deterioration in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of aging 2011-08-16 Brain scans and imaging

    While resting state functional connectivity has been shown to decrease in patients with mild and/or moderate Alzheimer's disease, it is not yet known how functional connectivity changes in patients as the disease progresses.

  50. Resting state fMRI in Alzheimer's disease: beyond the default mode network

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of aging 2011-08-03 Brain scans and imaging

    Using resting state (RS) functional magnetic resonance imaging (fMRI), the connectivity patterns of the default mode (DMN), frontoparietal, executive, and salience networks were explored in 13 Alzheimer's disease (AD) patients, 12 amnestic mild cognitive impairment (aMCI) patients, and 13 healthy controls.

From across this tag

5 of the 187 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 5. The same 5 appear here every time.

All topic tags with their study counts