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Multi-Nutrient Dietary Intervention Approach to the Management of Alzheimer's Disease - A Mini-Review
Blanka Klimova, Kamil Kuca. Current Alzheimer research, 2016
Topic: Gut, metabolism and diet
Alzheimer's disease (AD) is currently the most common incurable forms of dementia. The number of people affected by this disease is expected to grow rapidly in the next decades due to the present demographic changes. Since the pharmacological treatment of AD is quite costly, researchers try to look for alternative treatments for patients suffering from AD. One of such nonpharmacological approaches is nutritional intervention. The purpose of this minireview is to explore the issue of multi-nutrient intervention in the management of AD with special focus on medical foods and Mediterranean diet. The methods include a method of literature review of available sources, and a method of comparison of different research studies analyzing this topic. The findings of this review study indicate that multi-nutrient intervention seem to bring many benefits for AD patients such as the delay of cognitive decline, non-invasive and less costly treatment or none or fewer side effects. In addition, to minimize the risk of AD, a multi-factorial healthy lifestyle approach should be implemented by people already at their mid-life.
Key findings
- The findings of this review study indicate that multi-nutrient intervention seem to bring many benefits for AD patients such as the delay of cognitive decline, non-invasive and less costly treatment or none or fewer side effects.
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Study details
- Evidence strengthLow
How this study scored 38/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multi-centre collaboration and free to read, so those were left out: it earned 21 of the 56 points we could judge it on, which is 38 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Current Alzheimer research) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2016 — within 20 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 27335038) |
| Free to read | — / 2 | Access not recorded — left out of this score |
| Points | 21 / 56 | Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 21 of the 56 points we could judge it on is 38 out of 100. |
| Total | 38 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
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Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
APA 7th
Klimova, B., & Kuca, K. (2016). Multi-Nutrient Dietary Intervention Approach to the Management of Alzheimer's Disease - A Mini-Review. Current Alzheimer research. https://doi.org/10.2174/1567205013666160603000623
Vancouver
Klimova B, Kuca K. Multi-Nutrient Dietary Intervention Approach to the Management of Alzheimer's Disease - A Mini-Review. Current Alzheimer research. 2016. doi:10.2174/1567205013666160603000623. PMID: 27335038.
BibTeX
@article{klimova2016-27335038,
author = {Klimova, Blanka and Kuca, Kamil},
title = {{Multi-Nutrient Dietary Intervention Approach to the Management of Alzheimer's Disease - A Mini-Review}},
journal = {Current Alzheimer research},
year = {2016},
doi = {10.2174/1567205013666160603000623},
pmid = {27335038},
url = {https://doi.org/10.2174/1567205013666160603000623}
}
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