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disorder
492 studies tagged disorder, dated 1986-01-01 to 2026-03-31. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Synaptic loss in alcohol use disorder: clinical and mechanistic insights from a PET imaging study 2026-03-31
- Neighborhood environmental deprivation predicts the generalized neurocognitive deficit in schizophrenia 2025-12-19
- Bridging the Gap: Can Hippocampal Sclerosis Serve as a Surrogate Biomarker for LATE‐NC? 2025-12-01
Studies
492 studies carry this tag.
Date range
1986 to 2026
Top journals
- Neurology 38
- Biological psychiatry 36
- NeuroImage 32
- The American journal of psychiatry 22
- Proceedings of the National Academy of Sciences of the United States of America 20
148 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Future longitudinal studies with trauma control subjects and neuropsychological measures are indicated to further elucidate the relationship between hippocampus and behavioral abnormalities in young PTSD subjects.
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These findings are consistent with smaller hippocampal volume in adult subjects with chronic PTSD.
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Hippocampal atrophy has been related to mild cognitive impairment (MCI) and early Alzheimer disease (AD), but the diagnostic significance of cross-sectionally determined hippocampal volumes is still ambiguous.
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55/100
The authors hypothesize that there is a phase of increased medial temporal lobe activation early in the course of prodromal Alzheimer disease followed by a subsequent decrease as the disease progresses.
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Hippocampal volume was the primary determinant of memory decline, whereas executive function (EXEC) decline was related to multiple brain components.
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Studies have suggested that teens with alcohol use disorder (AUD) can demonstrate memory deficits, but the underlying neuroanatomical substrates are unclear.
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Self-esteem, the value we place on ourselves, has been associated with effects on health, life expectancy, and life satisfaction.
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47/100
Magnetic resonance (MR) imaging studies have identified hippocampal structural alterations in the pathogenesis of schizophrenia.
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Prematurity is associated with mild brain structural differences that persist at 8 years of age, with associated lower scores in neurocognitive assessments.
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40/100
The cornu ammonis 1 region of the hippocampus (CA1) sector of hippocampus is vulnerable to both Alzheimer's disease (AD)-type neurofibrillary degeneration and anoxia-ischemia.
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The new HipMask technique provides accurate and rapid assessment of the hippocampus on PET without the use of regions of interest.
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The APOE*E4 genotype status appears to have a greater deleterious effect on gross hippocampal pathology and memory performance in women than in men.
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Structural deformity of the hippocampus is characteristic of individuals with very mild and mild forms of dementia of the Alzheimer type (DAT).
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Recurrent depression is associated with smaller hippocampal volume which is most prominent in the posterior hippocampus.
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52/100
Although reduced hippocampal volumes are most pronounced in late-onset depression, older people with early-onset disorders also display volume changes and memory loss.
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The advance of neuroimaging techniques has resulted in a burgeoning of studies reporting abnormalities in brain structure and function in a number of neuropsychiatric disorders.
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Magnetic resonance imaging (MRI) has opened a new window to the brain.
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Over the last decade a significant number of studies have reported smaller hippocampal volume in individuals with symptoms of post-traumatic stress disorder (PTSD) relative to control groups, and in some cases hemispheric asymmetries in this effect have been noted.
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The birth of new neurons, or neurogenesis, in the hippocampal formation has been demonstrated throughout the lifetime of multiple species including humans.
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Early hypotheses on the pathophysiology of major depression were based on aberrant intrasynaptic concentrations of mainly the neurotransmitters serotonin and norepinephrine.
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PTSD is not a necessary condition for small hippocampal size in trauma-exposed individuals.
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This result replicates previous findings of smaller hippocampal volumes in PTSD patients, but in an underinvestigated population, suggesting that either smaller hippocampal volume is a predisposing factor in the development of PTSD or that damage occurs within months of trauma, rather than a number of years.
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Older depressed subjects have persisting cognitive impairments associated with hippocampal volume reduction, but the results do not support cortisol-mediated hippocampal neurotoxicity as the major etiological mechanism.
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In MDD, the packing density of glia, pyramidal neurons, and granule cell neurons is significantly increased in all hippocampal subfields and the dentate gyrus, and pyramidal neuron soma size is significantly decreased as well.
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Hippocampal volume is reduced in patients with unipolar depression, maybe as a consequence of repeated periods of major depressive disorder.
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Studies in macaque monkeys indicate that the perirhinal cortex in the temporal lobe participates in object memory.
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Converging lines of research suggest that the hippocampal complex (HC) may have a role in the pathophysiology of major depressive disorder (MDD).
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Atlas normalization, as commonly used by functional data analysis, provides an automated solution to the widely encountered problem of correcting for head size variation in regional and whole-brain morphometric analyses, so long as an age- and population-appropriate target atlas is used.
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There is wide agreement that spatial memory is dependent on the integrity of the hippocampus, but the importance of the hippocampus for nonspatial tasks, including tasks of object recognition memory is not as clear.
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Controversy persists regarding whether Alzheimer's disease (AD) is a distinct entity or instead exists on a continuum with nondemented aging.
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Application of magnetic resonance imaging (MRI) techniques reveals that human brain aging varies across cortical regions.
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We confirmed previous findings of smaller hippocampal volume in PTSD in a new population made up of police officers, excluding comorbidity as a confounder.
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Our results are consistent with previous findings of structural abnormalities of amygdala and hippocampus in subjects with recent-onset major depression.
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Hippocampal volume reduction has been reported in patients with borderline personality disorder (BPD), and is hypothesized to be associated with traumatic childhood experiences.
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43/100
Medication-free nonelderly depressed outpatients without alcohol dependence or adverse experiences in childhood had normal hippocampal volume.
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Autism is a neurodevelopmental disorder characterized by impairments in reciprocal social interaction, deficits in verbal and nonverbal communication, and a restricted repertoire of activities or interests.
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Participants with late-onset depression had bilateral hippocampal atrophy compared with those with early-onset depression and controls.
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Hippocampal atrophy (HA) is usually attributed to the neurofibrillary tangles and neuritic plaques of Alzheimer disease.
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In the dentate gyrus of the hippocampus, cell birth and maturation into neurons, or neurogenesis, occur throughout the lifetime of animals and humans.
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These results do not support the hypothesis that hippocampal volumes diminish during the 1-year follow-up period.
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Although the effect of major depressive disorder on amygdala volume remains to be conclusively established, inclusion of the amygdala with the hippocampus appears to have decreased the likelihood of detecting volumetric differences in either structure.
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Hippocampal volume reductions are widely observed in schizophrenia.
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41/100
Patients receiving chronic corticosteroid therapy have smaller hippocampal volumes, lower N-acetyl aspartate ratios, and declarative memory deficits compared with controls.
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Magnetic resonance imaging (MRI) has been suggested as a useful tool in early diagnosis of Alzheimer's disease (AD).
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The association of neurofibrillary tangles with delayed verbal recall may reflect associated hippocampal atrophy.
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Twenty patients with AD and 25 CN subjects had MRI scans and clinical evaluations twice approximately 1.9 years apart.
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Childhood abuse is linked to posttraumatic stress disorder (PTSD), which follows abuse survivors into adulthood.
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Our findings provide new evidence of abnormalities in the hippocampus in early onset depression.
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Animal studies on the effects of chronic variable stress during the peripubertal-juvenile period on hippocampal structure and function are lacking.
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Hypoxia damages multiple organ systems especially those with high oxygen utilization such as the central nervous system.
From across this tag
10 of the 492 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Evolution of spatial cognition: sex-specific patterns of spatial behavior predict hippocampal size
- Segmentation of the mouse hippocampal formation in magnetic resonance images
- Hippocampal volume is as variable in young as in older adults: implications for the notion of hippocampal atrophy in humans
- Hippocampal volume varies with educational attainment across the life-span
- Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: a magnetic resonance microscopy and stereologic analysis
- MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease
- Prefrontal cortex, negative symptoms, and schizophrenia: an MRI study
- Slowing gait and risk for cognitive impairment: The hippocampus as a shared neural substrate
- Hippocampal volume and everyday memory in children of very low birth weight
- Hippocampal development - old and new findings