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Home › Research › Topics › disorder

disorder

492 studies tagged disorder, dated 1986-01-01 to 2026-03-31. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Synaptic loss in alcohol use disorder: clinical and mechanistic insights from a PET imaging study 2026-03-31
  2. Neighborhood environmental deprivation predicts the generalized neurocognitive deficit in schizophrenia 2025-12-19
  3. Bridging the Gap: Can Hippocampal Sclerosis Serve as a Surrogate Biomarker for LATE‐NC? 2025-12-01

Studies

492 studies carry this tag.

Date range

1986 to 2026

Top journals

  • Neurology 38
  • Biological psychiatry 36
  • NeuroImage 32
  • The American journal of psychiatry 22
  • Proceedings of the National Academy of Sciences of the United States of America 20

148 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. In contrast to many other mammals, cetaceans have relatively small hippocampi that appear to lack adult neurogenesis

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Brain structure & function 2013-11-01 Hippocampus size on brain scans

    The hippocampus is essential for the formation and retrieval of memories and is a crucial neural structure sub-serving complex cognition.

  2. Higher glucose levels associated with lower memory and reduced hippocampal microstructure

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Neurology 2013-10-23 Hippocampus size on brain scans

    Our results indicate that even in the absence of manifest type 2 diabetes mellitus or impaired glucose tolerance, chronically higher blood glucose levels exert a negative influence on cognition, possibly mediated by structural changes in learning-relevant brain areas.

  3. Meditation's impact on default mode network and hippocampus in mild cognitive impairment: a pilot study

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Neuroscience letters 2013-10-10 Hippocampus size on brain scans

    Those with high baseline stress levels are more likely to develop mild cognitive impairment (MCI) and Alzheimer's Disease (AD).

  4. Childhood maltreatment and psychopathology: A case for ecophenotypic variants as clinically and neurobiologically distinct subtypes

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The American journal of psychiatry 2013-10-01 Hippocampus size on brain scans

    Phenotypic expression of psychopathology may be strongly influenced by exposure to maltreatment, leading to a constellation of ecophenotypes.

  5. Maternal anxiety and infants' hippocampal development: timing matters

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Translational psychiatry 2013-09-24 Hippocampus size on brain scans

    Exposure to maternal anxiety predicts offspring brain development.

  6. 3T MRI quantification of hippocampal volume and signal in mesial temporal lobe epilepsy improves detection of hippocampal sclerosis

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. AJNR. American journal of neuroradiology 2013-07-18 Hippocampus size on brain scans

    In 3T MRI visually inspected by experts, quantification of hippocampal volume and signal can increase the detection of hippocampal sclerosis in 28% of patients with mesial temporal lobe epilepsy.

  7. Mood and memory deficits in a model of Gulf War illness are linked with reduced neurogenesis, partial neuron loss, and mild inflammation in the hippocampus

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2013-06-28 Hippocampus size on brain scans

    Impairments in mood and cognitive function are the key brain abnormalities observed in Gulf war illness (GWI), a chronic multisymptom health problem afflicting ∼25% of veterans who served in the Persian Gulf War-1.

  8. Structural development of the hippocampus and episodic memory: developmental differences along the anterior/posterior axis

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Cerebral cortex (New York, N.Y. : 1991) 2013-06-25 Hippocampus size on brain scans

    The hippocampus is critically involved in episodic memory, yet relatively little is known about how the development of this structure contributes to the development of episodic memory during middle to late childhood.

  9. Mapping subcortical brain maturation during adolescence: evidence of hemisphere- and sex-specific longitudinal changes

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Developmental science 2013-06-11 Hippocampus size on brain scans

    Early to mid-adolescence is an important developmental period for subcortical brain maturation, but longitudinal studies of these neurodevelopmental changes are lacking.

  10. Hippocampal development - old and new findings

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Neuroscience 2013-06-10 Brain scans and imaging

    The hippocampus, derived from medial regions of the telencephalon, constitutes a remarkable brain structure.

  11. Sex differences in resilience to childhood maltreatment: effects of trauma history on hippocampal volume, general cognition and subclinical psychosis in healthy adults

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of psychiatric research 2013-05-30 Hippocampus size on brain scans

    Recent data suggests that a history of childhood maltreatment is associated with reductions in hippocampal volume in healthy adults.

  12. Neural predictors of individual differences in response to math tutoring in primary-grade school children

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2013-04-29 Hippocampus size on brain scans

    Now, more than ever, the ability to acquire mathematical skills efficiently is critical for academic and professional success, yet little is known about the behavioral and neural mechanisms that drive some children to acquire these skills faster than others.

  13. STEPS: Similarity and Truth Estimation for Propagated Segmentations and its application to hippocampal segmentation and brain parcelation

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Medical image analysis 2013-03-01 Hippocampus size on brain scans

    Anatomical segmentation of structures of interest is critical to quantitative analysis in medical imaging.

  14. The stress model of chronic pain: evidence from basal cortisol and hippocampal structure and function in humans

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Brain : a journal of neurology 2013-03-01 Hippocampus size on brain scans

    Recent theories have suggested that chronic pain could be partly maintained by maladaptive physiological responses of the organism facing a recurrent stressor.

  15. Structural changes in hippocampal subfields in major depressive disorder: a high-field magnetic resonance imaging study

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Biological psychiatry 2013-02-16 Hippocampus size on brain scans

    Hippocampal volumes in unmedicated MDD showed evidence of localization to specific subfields and subregions, findings that appear, on the surface, consistent with preclinical evidence for localized mechanisms of hippocampal neuroplasticity.

  16. Default mode network connectivity indicates episodic memory capacity in mesial temporal lobe epilepsy

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Epilepsia 2013-01-29 Hippocampus size on brain scans

    Our results demonstrate the striking clinical significance of the brain's intrinsic connectivity in evaluating cognitive capacity and indicating the potential of postsurgical cognitive morbidity in patients with mTLE.

  17. Hippocampal granule neuron number and dentate gyrus volume in antidepressant-treated and untreated major depression

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2013-01-07 Hippocampus size on brain scans

    Smaller hippocampal volume is reported in major depressive disorder (MDD).

  18. Hippocampal volume varies with educational attainment across the life-span

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Frontiers in human neuroscience 2012-11-09 Hippocampus size on brain scans

    Socioeconomic disparities-and particularly differences in educational attainment-are associated with remarkable differences in cognition and behavior across the life-span.

  19. Reduced hippocampal volume in healthy young ApoE4 carriers: an MRI study

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. PloS one 2012-11-09 Hippocampus size on brain scans

    The E4 allele of the ApoE gene has consistently been shown to be related to an increased risk of Alzheimer's disease (AD).

  20. Persistent cognitive impairment, hippocampal atrophy and EEG changes in sepsis survivors

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Journal of neurology, neurosurgery, and psychiatry 2012-11-07 Hippocampus size on brain scans

    This study demonstrates permanent cognitive impairment in several domains in both septic and non-septic ICU survivors and unspecific brain dysfunction.

  21. State-dependent changes in hippocampal grey matter in depression

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Molecular psychiatry 2012-11-06 Hippocampus size on brain scans

    Reduced hippocampal volume has been reported in depression and may be involved in the aetiology of depressive symptoms and vulnerability to depressive relapse.

  22. Gating of fear in prelimbic cortex by hippocampal and amygdala inputs

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuron 2012-11-01 Hippocampus size on brain scans

    The prefrontal cortex (PFC) regulates emotional responses, but it is unclear how PFC integrates diverse inputs to select the appropriate response.

  23. Statistical analysis of longitudinal neuroimage data with Linear Mixed Effects models

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. NeuroImage 2012-10-30 Hippocampus size on brain scans

    Longitudinal neuroimaging (LNI) studies are rapidly becoming more prevalent and growing in size.

  24. Cross-sectional and longitudinal association of body mass index and brain volume

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Human brain mapping 2012-09-24 Hippocampus size on brain scans

    Although a link between body mass index (BMI) and brain volume has been established in several cross-sectional studies, evidence of the association between change in BMI over time and changes in brain structure is limited.

  25. Exercise therapy, cardiorespiratory fitness and their effect on brain volumes: a randomised controlled trial in patients with schizophrenia and healthy controls

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2012-09-13 Hippocampus size on brain scans

    The objective of this study was to examine exercise effects on global brain volume, hippocampal volume, and cortical thickness in schizophrenia patients and healthy controls.

  26. Hippocampal sclerosis--origins and imaging

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Epilepsia 2012-09-01 Hippocampus size on brain scans

    If adequate MRI shows no structural correlate in patients with MTLE, functional imaging studies are valuable, especially if they are in agreement with ictal electroencephalography (EEG) findings.

  27. Investigating structural brain changes of dehydration using voxel-based morphometry

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. PloS one 2012-08-29 Mild cognitive impairment

    Dehydration can affect the volume of brain structures, which might imply a confound in volumetric and morphometric studies of normal or diseased brain.

  28. Common hippocampal structural and functional changes in migraine

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Brain structure & function 2012-07-04 Hippocampus size on brain scans

    The hippocampus is classically involved in memory consolidation, spatial navigation and is involved in the stress response.

  29. Prevalence, laterality, and comorbidity of hippocampal sclerosis in an autopsy sample

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Brain and behavior 2012-06-26 Brain scans and imaging

    Hippocampal sclerosis (HS) is a common and often asymmetric neuropathological finding among elderly persons who experience progressive memory loss, but its cause is unknown and it is rarely diagnosed during life.

  30. Reduced hippocampal volume and verbal memory performance associated with interleukin-6 and tumor necrosis factor-alpha levels in chemotherapy-treated breast cancer survivors

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Brain, behavior, and immunity 2012-06-12 Hippocampus size on brain scans

    Many survivors of breast cancer show significant cognitive impairments, including memory deficits.

  31. Stress abnormalities in individuals at risk for psychosis: a review of studies in subjects with familial risk or with "at risk" mental state

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Psychoneuroendocrinology 2012-06-02 Hippocampus size on brain scans

    Increased sensitivity to stress is known to play an important role in the transition to first episode psychosis (FEP).

  32. Neurocognitive impairment in obstructive sleep apnea

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Chest 2012-06-01 Hippocampus size on brain scans

    Obstructive sleep apnea syndrome (OSAS) is a common disorder with far-reaching health implications.

  33. Predictive neural biomarkers of clinical response in depression: a meta-analysis of functional and structural neuroimaging studies of pharmacological and psychological therapies

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Neurobiology of disease 2012-06-01 Hippocampus size on brain scans

    We performed a systematic review and meta-analysis of neural predictors of response to the most commonly used, evidence based treatments in clinical practice, namely pharmacological and psychological therapies.

  34. Childhood socioeconomic status and adult brain size: childhood socioeconomic status influences adult hippocampal size

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Annals of neurology 2012-05-01 Hippocampus size on brain scans

    A significant association between childhood SES and hippocampal volumes in late life is consistent with the established neurodevelopmental findings that early life conditions have an effect on structural brain development.

  35. Common variants at 12q14 and 12q24 are associated with hippocampal volume

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Nature genetics 2012-04-15 Hippocampus size on brain scans

    Aging is associated with reductions in hippocampal volume that are accelerated by Alzheimer's disease and vascular risk factors.

  36. Identification of common variants associated with human hippocampal and intracranial volumes

    ✓ Peer-reviewed alzhub usefulness score 79 out of 100. Nature genetics 2012-04-15 Hippocampus size on brain scans

    Identifying genetic variants influencing human brain structures may reveal new biological mechanisms underlying cognition and neuropsychiatric illness.

  37. Abnormalities in hippocampal functioning with persistent pain

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2012-04-01 Hippocampus size on brain scans

    Chronic pain patients exhibit increased anxiety, depression, and deficits in learning and memory.

  38. Teaching an adult brain new tricks: a critical review of evidence for training-dependent structural plasticity in humans

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. NeuroImage 2012-03-30 Hippocampus size on brain scans

    A growing number of structural neuroimaging studies have reported significant changes in gray matter density or volume and white matter microstructure in the adult human brain following training.

  39. Modifiable factors that alter the size of the hippocampus with ageing

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Nature reviews. Neurology 2012-03-13 Prevention and risk

    The hippocampus is particularly vulnerable to the neurotoxic effects of obesity, diabetes mellitus, hypertension, hypoxic brain injury, obstructive sleep apnoea, bipolar disorder, clinical depression and head trauma.

  40. How does the brain deal with cumulative stress? A review with focus on developmental stress, HPA axis function and hippocampal structure in humans

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Neurobiology of disease 2012-03-09 Hippocampus size on brain scans

    There is evidence that excessive stress exposure of the brain, mediated through the neurotoxic effects of cortisol and possibly neuroinflammation, causes damage to brain structure and function: the glucocorticoid cascade hypothesis.

  41. Long-term declarative memory deficits in diffuse TBI: correlations with cortical thickness, white matter integrity and hippocampal volume

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2012-03-08 Hippocampus size on brain scans

    We investigated structural brain damage in subjects who had suffered severe and diffuse traumatic brain injury (TBI), and examined its relationship with declarative memory impairment.

  42. Amygdala and hippocampal volume reductions as candidate endophenotypes for borderline personality disorder: a meta-analysis of magnetic resonance imaging studies

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Psychiatry research 2012-03-01 Hippocampus size on brain scans

    Borderline personality disorder (BPD) is a genetically influenced psychiatric illness with disruptions in neural systems supporting cognition and emotion regulation.

  43. Childhood maltreatment is associated with reduced volume in the hippocampal subfields CA3, dentate gyrus, and subiculum

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2012-02-13 Hippocampus size on brain scans

    Childhood maltreatment or abuse is a major risk factor for mood, anxiety, substance abuse, psychotic, and personality disorders, and it is associated with reduced adult hippocampal volume, particularly on the left side.

  44. Maternal support in early childhood predicts larger hippocampal volumes at school age

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2012-01-30 Hippocampus size on brain scans

    Early maternal support has been shown to promote specific gene expression, neurogenesis, adaptive stress responses, and larger hippocampal volumes in developing animals.

  45. Spatial navigation impairment is proportional to right hippocampal volume

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2012-01-30 Hippocampus size on brain scans

    Cognitive deficits in older adults attributable to Alzheimer's disease (AD) pathology are featured early on by hippocampal impairment.

  46. Fornix integrity and hippocampal volume predict memory decline and progression to Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2012-01-01 Mild cognitive impairment

    Fornix FA both cross-sectionally correlated with and longitudinally predicted memory decline and progression to AD.

  47. Hippocampal atrophy and ventricular enlargement in normal aging, mild cognitive impairment (MCI), and Alzheimer Disease

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Alzheimer disease and associated disorders 2012-01-01 Getting a diagnosis

    Alzheimer disease (AD) is the most common type of dementia worldwide.

  48. Memory after silent stroke: hippocampus and infarcts both matter

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Neurology 2012-01-01 Brain scans and imaging

    Both hippocampal volume and brain infarcts independently contribute to memory performance in elderly individuals without dementia.

  49. Global and focal brain volume in long-term breast cancer survivors exposed to adjuvant chemotherapy

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Breast cancer research and treatment 2011-12-29 Hippocampus size on brain scans

    A limited number of studies have associated adjuvant chemotherapy with structural brain changes.

  50. A hippocampal marker of recollection memory ability among healthy young adults: contributions of posterior and anterior segments

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuron 2011-12-01 Hippocampus size on brain scans

    The hippocampus is known to support recollection memory, but the relation between its structure and recollection in healthy adults has not been established.

From across this tag

10 of the 492 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

All topic tags with their study counts