Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest in this topic

  1. Public awareness of the hearing loss-dementia link and self-reported behavioral changes in middle- to older-aged Canadians 2026-09-26
  2. Patterns of modifiable lifestyle, behavioural and health-related risk factors and their associations with incident dementia in UK Biobank 2026-09-25
  3. Excess hypoglycaemia-related hospitalisation in older adults with comorbid type 2 diabetes and dementia: a UK Biobank cohort study 2026-09-16

Studies

1,139 studies carry this tag.

Date range

1978 to 2026

Top journals

  • Neurology 134
  • Alzheimer s & Dementia 52
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 33
  • Journal of the American Geriatrics Society 32
  • JAMA neurology 27

362 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Ultra‐processed food intake, cognitive function, and dementia risk: A cross‐sectional study of middle‐aged and older Australian adults

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring 2026-04-01 Prevention trials

    Each 10% increase in UPF intake was associated with lower attention scores (-0.05 points) and higher dementia risk (+0.24 points), independent of Mediterranean diet adherence.

  2. Delirium, long-term conditions, and incident dementia in older adults admitted to hospital for emergency care in Lothian, Scotland: a population-based cohort study

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. The lancet. Healthy longevity 2026-03-27 How common it is

    Of 23 558 people without pre-existing dementia, 4135 (17·6%) had an admission with delirium.

  3. Dementia Burden and Modifiable Risk Factors in Type 2 Diabetes: Population Based, Prospective Cohort Study

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. Diabetes Obesity and Metabolism 2026-03-26 Risk factors

    T2D was associated with a higher risk and earlier onset of dementia, especially in cases with T2D diagnosed at ages 30-54 years.

  4. Association between zinc deficiency and adverse outcomes in patients with dementia: a matched cohort study

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Frontiers in Nutrition 2026-03-20 How common it is

    In this observational study, zinc deficiency was associated with increased 1-year mortality and infection-related complications in patients with dementia, with evidence of a dose–response relationship.

  5. Coffee and Tea Intake, Dementia Risk, and Cognitive Function

    ✓ Peer-reviewed alzhub usefulness score 73 out of 100. JAMA 2026-03-17 Prevention and risk

    Greater consumption of caffeinated coffee and tea was associated with lower risk of dementia and modestly better cognitive function, with the most pronounced association at moderate intake levels.

  6. Late-life body mass index and Alzheimer disease conversion in mild cognitive impairment: Nonlinear risk and structural MRI correlates

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Archives of Gerontology and Geriatrics 2026-03-13 Brain scans and imaging

    Over a median follow-up of 3.26 years, 321 participants converted to AD.

  7. Risk Adjustment for Alzheimer Disease and Related Dementias in Medicare Advantage and Health Care Experiences

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. JAMA Network Open 2026-03-13 Health systems and care delivery

    Among 5353 MA beneficiary observations (1239 [23.1%] aged 65-74 years; 3127 [58.4%] aged ≥75 years; 1785 male [33.3%]), 1629 (30.4%) reported a diagnosis of ADRD, and 3724 (69.6%) did not report an ADRD diagnosis.

  8. Mapping social health and dementia risk: A register-based study of older adults in Finland

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Social Science & Medicine 2026-03-05 Risk factors

    This study investigates the role of individual and area-level social health factors in shaping geographic variation in dementia incidence among older adults in Finland.

  9. Machine Learning-Based Sleep Electroencephalographic Brain Age Index and Dementia Risk: An Individual Participant Data Meta-Analysis

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. JAMA network open 2026-03-02 Biomarkers

    Across the cohorts, each 10-year increase in BAI was associated with a 39% higher risk of incident dementia (hazard ratio [HR], 1.39 [95% CI, 1.21-1.59]; P Conclusions and relevance In this IPD meta-analysis, a higher sleep EEG-based BAI was associated with a higher risk of incident dementia.

  10. Impact of anticoagulation on cognitive decline and clinical outcomes in patients with atrial fibrillation and dementia: A retrospective cohort study

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Journal of Alzheimer s Disease Reports 2026-03-01 Cognitive tests and assessment

    In this retrospective, confounder-adjusted study, anticoagulation was associated with slower cognitive/functional decline and lower hospitalization/mortality risk in AF and dementia patients.

  11. Long‐term adherence and changes in the Mediterranean and MIND diets in relation to dementia risk and cognitive function

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Alzheimer s & Dementia 2026-03-01 Prevention trials

    Participants in the highest versus lowest MedDiet and MIND categories had 21% (hazard ratio [HR] = 0.79, 95% confidence interval [CI]: 0.73-0.84) and 14% (HR = 0.86, 95% CI: 0.81-0.91) lower dementia risk, respectively.

  12. Development and validation of the LateDem-Risk score to predict dementia incidence in the InveCe.Ab and Trelong Italian cohorts

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Scientific Reports 2026-02-14 How common it is

    Identifying older adults at increased dementia risk is a public health priority.

  13. Associations of Lifetime Cognitive Enrichment With Incident Alzheimer Disease Dementia, Cognitive Aging, and Cognitive Resilience

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Neurology 2026-02-11 Brain tissue and pathology

    = 0.02). Lifetime exposure to cognitive enrichment was related to lower risk of AD dementia and a slower rate of cognitive decline, including after adjustment for common ADRD pathologies, indicating higher resilience provided by lifetime enrichment.

  14. Recombinant zoster vaccine is associated with a reduced risk of dementia

    ✓ Peer-reviewed alzhub usefulness score 68 out of 100. Nature Communications 2026-02-09 Prevention and risk

    Vaccines to prevent herpes zoster have been associated with reduced dementia risk.

  15. Associations between low-dose drinking water lithium exposure and Dementia: A nationwide U.S. ecological study

    ✓ Peer-reviewed alzhub usefulness score 35 out of 100. Environmental pollution (Barking, Essex : 1987) 2026-02-06 Risk factors

    Lithium is a naturally occurring trace element with established neuroprotective and psychotropic properties at pharmacologic doses.

  16. Risks of dementia and stroke in patients with hypertension using telmisartan or other renin‑angiotensin system inhibitors

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Alzheimer s & Dementia 2026-02-01 Vascular contributions

    The telmisartan group had the lowest risk of all dementias (telmisartan vs NT-ARB: hazard ratio [HR]: 0.78; 95% confidence interval [CI]: 0.60 to 1.01; telmisartan vs angiotensin-converting enzyme inhibitor: HR: 0.67; 95% CI: 0.48 to 0.94).

  17. Urinary tract infection‐related delirium in Alzheimer's disease and related dementias: Clinical challenges and translational opportunities

    ✓ Peer-reviewed alzhub usefulness score 37 out of 100. Alzheimer s & Dementia 2026-02-01 Clinical safety

    Alzheimer's disease and related dementias (ADRD) affects millions of patients worldwide and is a leading cause of morbidity in older adults.

  18. Causality between Alzheimer disease and delirium: A two-sample Mendelian randomization study and gene colocalization analyses

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Medicine 2026-01-30 Genetics

    To evaluate the possible causality between Alzheimer disease (AD) and delirium, a two-sample Mendelian randomization (MR) method and gene colocalization strategy were employed.

  19. Dynamic trends, spatial clustering, and multi-model projections of the global burden of Alzheimer’s disease and other dementias: an analysis of GBD 1990–2021 data to 2050

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Frontiers in Aging Neuroscience 2026-01-30 Risk factors

    From 1990 to 2021, global ADOD burden increased markedly in absolute terms.

  20. Traumatic Brain Injury and All-Cause and Dementia-Related Mortality in the Framingham Heart Study

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. JAMA Network Open 2026-01-30 Long-term cohort studies

    This study included 10 333 FHS

  21. Life-Course Psychosocial Stress and Risk of Dementia and Stroke in Middle-Aged and Older Adults

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. JAMA Network Open 2026-01-28 Vascular contributions

    Among 11 601 participants (mean [SD] age, 59.18 [9.41] years; 5569 male [48.0%]), 9145 (78.8%) were exposed to at least 1 ACE indicator, 4241 (36.6%) to at least 1 AAE indicator, and 3531 (30.4%) to both ACE and AAE markers.

  22. Alcohol use and risk of dementia in diverse populations: evidence from cohort, case-control and Mendelian randomisation approaches

    ✓ Peer-reviewed alzhub usefulness score 68 out of 100. BMJ Evidence-Based Medicine 2026-01-21 Prevention and risk

    These findings provide evidence for a relationship between all types of alcohol use and increased dementia risk.

  23. From Anxiety, Depression to Major Neurocognitive Disorders: Exploring Their Association With the Risk Factors for Dementia

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Cureus 2026-01-21 Risk factors

    Dementia presents an escalating public health challenge worldwide.

  24. Glymphatic system dysfunction as a predictor of cognitive decline and incident dementia

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Journal of Alzheimer s Disease 2026-01-21 Getting a diagnosis

    This longitudinal evidence supports a link between the ALPS-I and cognitive degeneration.

  25. Association between plant-based diets and incident dementia: results from prospective cohort studies and a meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. The journal of prevention of Alzheimer's disease 2026-01-20 Prevention and risk

    In the cohort analyses, 891 incident dementia cases were identified over 166,762 person-years.

  26. Effects of Dementia on Adverse Outcomes in Geriatric Patients Undergoing Elective Total Hip Arthroplasty: Analysis of the US Nationwide Inpatient Sample

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Geriatric Orthopaedic Surgery & Rehabilitation 2026-01-16 Clinical safety

    376 323 elective geriatric THA patient samples from the NIS database were included, with an overall dementia prevalence of 2.05%.

  27. Emergency Department Hallways Are Associated With Incident Delirium and Severe Agitation in Older Adults Living With Dementia

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Journal of the American Geriatrics Society 2026-01-16 Clinical safety

    Our sample included 11,105 patients (median age 77, 51% female), with 2299 in the hallway group and 8806 in the non-hallway group.

  28. Associations of Vestibular Disorders With Risk of All‐Cause and Cause‐Specific Dementia: A Longitudinal Cohort Study in UK Biobank

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Sensory Neuroscience 2026-01-14 Long-term cohort studies

    Vestibular disorders were linked to higher risks of all‐cause dementia (HR 1.86 and 95% CI 1.04–3.30), Alzheimer's disease (AD, 2.36, and 1.01–5.51), and vascular dementia (VD, 3.35, and 1.48–7.59).

  29. Nutritional and physical pathways from feeding difficulty to sarcopenia in Alzheimer’s dementia

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. Frontiers in Nutrition 2026-01-12 Prevention trials

    Individuals with Alzheimer’s dementia exhibited poorer nutritional status (EdFED: 8.0 vs. 2.0; NUFFE: 10.0 vs. 7.0; both p < 0.001) and lower adherence to the Mediterranean diet (6.0 vs. 7.0; p = 0.050).

  30. Systemic complement factors in aging, Alzheimer's disease and other dementias: a longitudinal study over 10 years

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Molecular Neurodegeneration 2026-01-12 Laboratory science

    The results of this study indicate an AD-specific peripheral complement signature associated with disease development, highlighting complement factors as critical immune mediators that link aging and AD.

  31. Depression and risk of cognitive decline and dementia: Implications and strategies for prevention

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of Geriatric Mental Health 2026-01-01 Prevention trials

    Dementia, a syndrome characterized by a decline in cognitive function beyond what is expected from normal aging, poses a significant global health challenge.

  32. Midlife and late‐life population attributable fractions of risk factors for dementia in the United States: The Dementia Risk Prediction Project

    ✓ Peer-reviewed alzhub usefulness score 73 out of 100. Alzheimer s & Dementia 2026-01-01 Risk factors

    Midlife and late-life risk factors contributed to 22.7% and 16.5% of total dementia cases, respectively.

  33. Prediabetes as a critical stage for risk of dementia and stroke: evidence from the UK Biobank and Mendelian randomization.:evidence from the UK Biobank and Mendelian Randomization

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Pure Amsterdam UMC 2026-01-01 Long-term cohort studies

    During a median 13.7 years of follow-up, prediabetes (n=52,693) was associated with higher risks of vascular dementia (hazard ratio (HR):1.36; 95% confidence interval (CI): 1.14-1.61), stroke (HR:1.09; 95% CI: 1.01-1.16), ischemic stroke (HR:1.10; 95% CI: 1.02-1.19), and intracerebral hemorrhage (HR:1.19; 95% CI: 1.01-1.39) compared with normoglycemia, after adjustment for major confounding factors and across extensive sensitivity analyses.

  34. The potential for dementia prevention in Japan: a population attributable fraction calculation for 14 modifiable risk factors and estimates of the impact of risk factor reductions

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. The Lancet Regional Health - Western Pacific 2026-01-01 Risk factors

    The weighted combined PAF for all 14 risk factors was 38.9%, indicating that nearly 4 in 10 dementia cases in Japan might be preventable.

  35. Associations between joint air pollution exposure, mental health, and physical health and dementia incidence in an aging U.S. cohort

    ✓ Peer-reviewed alzhub usefulness score 39 out of 100. The Journals of Gerontology Series B 2025-12-30 How common it is

    We found significant associations between ADRD risk and particulate matter <2.5 µm in diameter and nitrogen dioxide in women.

  36. Association Between Circadian Rest-Activity Rhythms and Incident Dementia in Older Adults

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Neurology 2025-12-29 Disparities

    Of the 2,183 participants (mean ± SD age 79 ± 4.5 years, 58% female, 24% Black), 176 (8%) developed dementia.

  37. Differential Associations of Lipid Profiles with Dementia and Cardiovascular Disease: Findings from the UK Biobank Cohort

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Yonsei Medical Journal 2025-12-25 Long-term cohort studies

    High LDL-C (≥160 mg/dL) increased AD risk across all groups {hazard ratio (HR): 1.23 [95% confidence interval (CI): 1.10-1.38],p<0.001;HR: 1.45 (95% CI: 1.08-1.93),p=0.013;HR: 1.25 (95% CI: 1.10-1.42),p<0.001, respectively}, whereas low LDL-C (<70 mg/dL) showed higher VD risk in those not taking cholesterol-lowering medication [HR: 3.02 (95% CI: 1.73-5.27),p<0.001].Low HDL-C (≤40 mg/dL) was associated with increased AD and VD risk in non-users.

  38. Menopause hormone therapy and risk of mild cognitive impairment or dementia: a systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. The Lancet Healthy Longevity 2025-12-22 Prevention and risk

    No significant association was found between MHT use and risk of mild cognitive impairment or dementia.

  39. High Body Mass Index as a Causal Risk Factor for Vascular-Related Dementia: A Mendelian Randomization Study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. The Journal of Clinical Endocrinology & Metabolism 2025-12-16 Risk factors

    In a meta-analysis of 2 one-sample MR studies, the odds ratio (OR) for 1-SD higher BMI in predicting vascular-related dementia was 1.63 (95% CI, 1.13-2.35).

  40. Specific midlife depressive symptoms and long-term dementia risk: a 23-year UK prospective cohort study

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Lancet Psychiatry 2025-12-15 Prevention and risk

    A distinct set of midlife depressive symptoms was associated with an increased risk of dementia, suggesting that these symptoms might be early markers of underlying neurodegenerative processes.

  41. Periodontitis and incident cognitive decline and dementia: A 15-year prospective cohort study of older men residing in Northern Ireland

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Journal of Alzheimer s Disease 2025-12-12 Getting a diagnosis

    BackgroundPeriodontitis is a chronic bacterial infection that elicits systemic inflammation.

  42. Synergistic impacts of physical activity and sleep on risk of dementia and all-cause mortality in Chinese older stroke survivors

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of Stroke and Cerebrovascular Diseases 2025-12-11 Vascular contributions

    Older stroke survivors engaging in regular PA had a 38 % reduced risk of dementia [Odds Ratio (OR) =0.62, 95 % Confidence Interval (CI): 0.56-0.69, P < 0.001] and a 44 % lower risk of mortality [Hazard Ratio (HR) =0.56, 95 % CI: 0.52-0.59, P < 0.001].

  43. Projected extreme temperature event-attributable dementia deaths in China: a climate–ageing–adaptation framework

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. EBioMedicine 2025-12-09 Risk factors

    Without adaptation, ADD heatwave-attributable deaths are projected to rise sharply, especially under rapid socioeconomic development with high greenhouse gas emissions scenario (SSP5-RCP8.5) in the 2080s, which reach 59,088-an 11-fold (+1003%) increase comparing to 2010s levels.

  44. Metabolomic aging clock predicts risk of different cardiovascular diseases in the UK Biobank

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Metabolism 2025-12-08 Long-term cohort studies

    Current metabolomic aging clocks inadequately capture individual heterogeneity in biological aging trajectories, constraining their clinical utility.

  45. Sleep and physical activity trade-offs and dementia risk: a prospective cohort study in UK Biobank participants

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. BMC Medicine 2025-12-03 Long-term cohort studies

    The mean age of the sample was 63 years (Q1, Q3, 56, 68); 56% were women.

  46. Continuous Glucose Monitoring in Insulin-Treated Older Adults With Diabetes and Alzheimer Disease and Related Dementias

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. JAMA Network Open 2025-12-02 Risk factors

    In this cohort of 2022 insulin-treated older adults with diabetes and ADRD (1011 CGM users and 1011 SMBG users; mean [SD] age, 76.4 [6.7] years; 1133 female [56.0%]), CGM use was significantly associated with lower risk of all-cause hospitalization (hazard ratio [HR], 0.86; 95% CI, 0.76-0.96) and mortality (HR, 0.57; 95% CI, 0.48-0.67) compared with SMBG use.

  47. Of the 250 participants, 121 (48.4%) were female and the mean age at follow-up was 76.06 (SD 0.48).

  48. Association between falls and dementia risk: Evidence from three cohort studies

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Journal of Translational Internal Medicine 2025-12-01 How common it is

    Falls are an early sign of dementia risk, and genetic susceptibility facilitates this association.

  49. Associations of Cardiovascular‐Kidney‐Metabolic Syndrome with Psychiatric Disorders and Dementia in Midlife and Older adults in the UK Biobank

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Alzheimer s & Dementia 2025-12-01 Long-term cohort studies

    Among 389,314 participants, CKM stages were distributed as follows: stage 0 (10.0%), stage 1 (8.0%), stage 2 (57.6%), stage 3 (17.9%), and stage 4 (6.5%).

  50. Associations of Mid‐to‐Late Life Neighborhood Disadvantage with Cognitive Trajectories and Dementia Outcomes in the Health and Retirement Study

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Alzheimer s & Dementia 2025-12-01 Risk factors

    The sample (n = 26,728) was equally distributed across gender (55.1% women) and education (50.8% completed HS/GED diploma), and 30% came from under-represented racial/ethnic groups.

From across this tag

9 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.

All topic tags with their study counts