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Prevalence, incidence and modifiable factors for subtypes of mild cognitive impairment: results from the Longitudinal Ageing Study in China
Tao Wang, Haining He, Yanchen Shi, Ning Su, Minjie Zhu, Yan Feng, Yuanyuan Liu, Juan Li et al.. General Psychiatry, 2025-03-07
Topic: Risk, prevention and care in population studies
Among our participants, aMCI and VCIND demonstrated prevalence of 14.83% and 2.71%, respectively, and annual incidence (per 1000 person-years) of 69.6 and 10.6, respectively. The risk factor for aMCI was age, whereas its protective factors were high education level, tea consumption and physical activity. Moreover, VCIND risk factors were age, hypertension and depression. The presence of endocrine disease, cerebral trauma or hypertension was associated with a faster decline in cognition over 1 year. MCI is a serious health problem in China that will only worsen as the population ages if no widespread interventions are implemented. Preventive strategies that promote brain activity and support healthy lifestyle choices are required. We identified modifiable factors for MCI in older individuals. The easy-to-adopt solutions such as tea consumption and physical activity can aid in preventing MCI. Trial registration number: NCT03672448.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Wang, T., He, H., Shi, Y., Su, N., Zhu, M., Feng, Y., et al. (2025). Prevalence, incidence and modifiable factors for subtypes of mild cognitive impairment: results from the Longitudinal Ageing Study in China. General Psychiatry. https://doi.org/10.1136/gpsych-2024-101736
Vancouver
Wang T, He H, Shi Y, Su N, Zhu M, Feng Y, et al. Prevalence, incidence and modifiable factors for subtypes of mild cognitive impairment: results from the Longitudinal Ageing Study in China. General Psychiatry. 2025. doi:10.1136/gpsych-2024-101736. PMID: 40070969.
BibTeX
@article{wang2025-40070969,
author = {Wang, Tao and He, Haining and Shi, Yanchen and Su, Ning and Zhu, Minjie and Feng, Yan and Liu, Yuanyuan and Li, Juan and others},
title = {{Prevalence, incidence and modifiable factors for subtypes of mild cognitive impairment: results from the Longitudinal Ageing Study in China}},
journal = {General Psychiatry},
year = {2025},
doi = {10.1136/gpsych-2024-101736},
pmid = {40070969},
url = {https://doi.org/10.1136/gpsych-2024-101736}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
Key findings
- Among our participants, aMCI and VCIND demonstrated prevalence of 14.83% and 2.71%, respectively, and annual incidence (per 1000 person-years) of 69.6 and 10.6, respectively.
- The risk factor for aMCI was age, whereas its protective factors were high education level, tea consumption and physical activity.
- Moreover, VCIND risk factors were age, hypertension and depression.
- The presence of endocrine disease, cerebral trauma or hypertension was associated with a faster decline in cognition over 1 year.
- MCI is a serious health problem in China that will only worsen as the population ages if no widespread interventions are implemented.
Why it matters
In a Chinese cohort, age raised the risk of both amnestic and vascular mild cognitive impairment, while higher education, tea consumption and physical activity were protective for the amnestic type. The authors suggest these easy-to-adopt lifestyle factors could help prevent mild cognitive impairment, though the study was observational.
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Study details
- Study designlongitudinal study
- Participants2,051
- Effect size14.83%; 2.71%
- Evidence strengthModerate
How this study scored 57/100
Published in a peer-reviewed journal, and it is a longitudinal study following the same people over time. Scored zero for randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (General Psychiatry) |
| Journal's citation record | 0 / 4 | General Psychiatry: journal h-index 50 (OpenAlex, 2026-10-29) |
| Study design | 7 / 12 | A longitudinal study following the same people over time |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 3 / 4 | 2,051 participants |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 2 / 7 | Cited 7 times (OpenAlex, 2026-10-10) |
| Citations per year | 1 / 5 | 2.3 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 3 / 6 | Cited 4.4× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 1 / 4 | Cited 7 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Shifu Xiao: h-index 38 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | Chinese Academy of Sciences: institution h-index 1,801 (OpenAlex) |
| Multi-centre collaboration | 3 / 3 | OpenAlex lists 19 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 40070969) |
| Free to read | 2 / 2 | Free to read |
| Total | 57 / 100 | — |
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Read the original
- DOI: 10.1136/gpsych-2024-101736
- PubMed: 40070969
- Original source →
- Free full text: General Psychiatry →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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