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Neighborhood disadvantage and dementia incidence in a cohort of Asian American and non‐Latino White older adults in Northern California
Taylor M. Mobley, Crystal L. Shaw, Eleanor Hayes‐Larson, Joseph Fong, Paola Gilsanz, Gilbert C. Gee, Ron Brookmeyer, Rachel A. Whitmer et al.. Alzheimer s & Dementia, 2022-04-06
Topic: Risk, prevention and care in population studies
Among non-Latino Whites, ADI was associated with dementia incidence (most vs. least disadvantaged ADI quintile HR = 1.09, 95% confidence interval [CI] = 1.02-1.15). Among Asian Americans, associations were close to null (e.g., most vs. least disadvantaged ADI quintile HR = 1.01, 95% CI = 0.85-1.21). ADI was associated with dementia incidence among non-Latino Whites but not Asian Americans. Understanding the potentially different mechanisms driving dementia incidence in these groups could inform dementia prevention efforts.
Key findings
- Among non-Latino Whites, ADI was associated with dementia incidence (most vs. least disadvantaged ADI quintile HR = 1.09, 95% confidence interval [CI] = 1.02-1.15).
- Among Asian Americans, associations were close to null (e.g., most vs. least disadvantaged ADI quintile HR = 1.01, 95% CI = 0.85-1.21).
- ADI was associated with dementia incidence among non-Latino Whites but not Asian Americans.
- Understanding the potentially different mechanisms driving dementia incidence in these groups could inform dementia prevention efforts.
Why it matters
Among non-Latino White older adults, living in a more disadvantaged neighborhood was linked to a slightly higher rate of dementia, while among Asian Americans the link was close to none. The reasons for these different patterns are not yet understood.
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Study details
- Participants18,103
- Effect sizeHR = 1.09; HR = 1.01
- Evidence strengthLow
How this study scored 56/100
Published in a peer-reviewed journal. Scored zero for study design and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Alzheimer s & Dementia) |
| Journal's citation record | 2 / 4 | Alzheimer s & Dementia: journal h-index 228 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 3 / 5 | 2022 — within 6 year(s) of the newest study here |
| Sample size | 4 / 4 | 18,103 participants |
| Effect reported | 3 / 3 | Effect reported with a statistic (interval, p-value, ratio or similar) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 3 / 7 | Cited 33 times (OpenAlex, 2026-10-10) |
| Citations per year | 2 / 5 | 5.5 citations a year over 6 year(s) since 2022 |
| Impact for its field and year | 3 / 6 | Cited 4.1× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 3 / 6 | Cited by 10 other studies in this library |
| Still being cited | 2 / 4 | Cited 24 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Elizabeth Rose Mayeda: h-index 43 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | University of California, Los Angeles: institution h-index 1,923 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 7 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 35388625) |
| Free to read | 2 / 2 | Free to read |
| Total | 56 / 100 | — |
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Read the original
- DOI: 10.1002/alz.12660
- PubMed: 35388625
- Original source →
- Free full text: eScholarship (California Digital Library) →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Mobley, T. M., Shaw, C. L., Hayes‐Larson, E., Fong, J., Gilsanz, P., Gee, G. C., et al. (2022). Neighborhood disadvantage and dementia incidence in a cohort of Asian American and non‐Latino White older adults in Northern California. Alzheimer s & Dementia. https://doi.org/10.1002/alz.12660
Vancouver
Mobley TM, Shaw CL, Hayes‐Larson E, Fong J, Gilsanz P, Gee GC, et al. Neighborhood disadvantage and dementia incidence in a cohort of Asian American and non‐Latino White older adults in Northern California. Alzheimer s & Dementia. 2022. doi:10.1002/alz.12660. PMID: 35388625.
BibTeX
@article{mobley2022-35388625,
author = {Mobley, Taylor M. and Shaw, Crystal L. and Hayes‐Larson, Eleanor and Fong, Joseph and Gilsanz, Paola and Gee, Gilbert C. and Brookmeyer, Ron and Whitmer, Rachel A. and others},
title = {{Neighborhood disadvantage and dementia incidence in a cohort of Asian American and non‐Latino White older adults in Northern California}},
journal = {Alzheimer s \& Dementia},
year = {2022},
doi = {10.1002/alz.12660},
pmid = {35388625},
url = {https://doi.org/10.1002/alz.12660}
}
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