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Behavioural symptoms in patients with Alzheimer's disease and their association with cognitive impairment
Fernández M, Gobartt AL, Balañá M, COOPERA Study Group.. BMC neurology, 2010-09-28
Topic: Amyloid, tau and blood-test diagnosis
Plain-language summary
Background Behavioural and psychological symptoms of dementia (BPSD) are non-cognitive symptoms commonly associated to Alzheimer's disease (AD). The characterization of the clinical profile of AD patients might help to better understand disease evolution and to improve diagnosis and treatment. Thus, the aim of the present study is to describe the clinical profile of AD patients, and to correlate the presence of BPSD with the severity of the disease.
What this study adds
Evidence grade: Low
This is a cross-sectional study of 1,014 participants. This cross-sectional study described the clinical profile of people with Alzheimer's disease in Spain and looked at how behavioural and psychological symptoms relate to disease severity. It is observational and aimed at understanding disease evolution and improving diagnosis and treatment, not at testing a cure or prevention.
Taken from this record’s own fields, not from reading the paper. The grade is assigned from the abstract’s wording; what that means.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Fernández, M., Gobartt, A. L., Balañá, M., & COOPERA Study Group. (2010). Behavioural symptoms in patients with Alzheimer's disease and their association with cognitive impairment. BMC neurology. https://doi.org/10.1186/1471-2377-10-87
Vancouver
Fernández M, Gobartt AL, Balañá M, COOPERA Study Group. Behavioural symptoms in patients with Alzheimer's disease and their association with cognitive impairment. BMC neurology. 2010. doi:10.1186/1471-2377-10-87. PMID: 20920205.
BibTeX
@article{fernandez2010-20920205,
author = {Fernández, M. and Gobartt, A. L. and Balañá, M. and {COOPERA Study Group}},
title = {{Behavioural symptoms in patients with Alzheimer's disease and their association with cognitive impairment}},
journal = {BMC neurology},
year = {2010},
doi = {10.1186/1471-2377-10-87},
pmid = {20920205},
url = {https://doi.org/10.1186/1471-2377-10-87}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
Key findings
- The characterization of the clinical profile of AD patients might help to better understand disease evolution and to improve diagnosis and treatment.
- Thus, the aim of the present study is to describe the clinical profile of AD patients, and to correlate the presence of BPSD with the severity of the disease.
- Methods A cross-sectional, observational and multicenter study was conducted at 115 centres in Spain.
- Patients suffering from AD with higher and lower BPSD scores (ADAS-Noncog score 26-50 and ≤25, respectively) were included.
Why it matters
This cross-sectional study described the clinical profile of people with Alzheimer's disease in Spain and looked at how behavioural and psychological symptoms relate to disease severity. It is observational and aimed at understanding disease evolution and improving diagnosis and treatment, not at testing a cure or prevention.
Study details
- Study designcross-sectional
- Participants1,014
- Evidence strengthLow
How this study scored 51/100
Published in a peer-reviewed journal, and it is a snapshot of people at one point in time. Scored zero for effect reported and randomized / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (BMC neurology) |
| Journal's citation record | 1 / 4 | BMC Neurology: journal h-index 122 (OpenAlex, 2026-10-29) |
| Study design | 4 / 12 | A snapshot of people at one point in time |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2010 — within 20 year(s) of the newest study here |
| Sample size | 3 / 4 | 1,014 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomized / blinded | 0 / 2 | No randomization or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 169 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 9.4 citations a year over 18 year(s) since 2010 |
| Impact for its field and year | 3 / 6 | Cited 6.6× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 1 / 6 | Cited by 1 other studies in this library |
| Still being cited | 2 / 4 | Cited 28 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 1 / 4 | Last-listed author M Balañá: h-index 6 (OpenAlex, whole career) |
| Institution's track record | 0 / 3 | Hospital de Cruces: institution h-index 277 (OpenAlex) |
| Multicenter collaboration | 2 / 3 | PubMed indexes it as a multicentre study |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 20920205) |
| Free to read | 2 / 2 | Free to read |
| Total | 51 / 100 | — |
What each of these 20 components measures, and what this score is not →
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Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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