- 1,803studies in the library match, of 29,380
- 870name it in the title
- 1964–2027years published
- 1,755peer-reviewed articles
The query: title or abstract mentions "Mediterranean", "MIND diet", "DASH diet", "diet"/"dietary", "nutrition"/"nutrient", "omega-3", "vitamin", "supplementation" or "microbiome/microbiota", matched case-insensitively against each record's title and abstract (its summary field) in alzhub's library of 29,380 study records, as of 2026-11-08. Every count on this page comes from that match. The matched list as JSON.
Most diet evidence comes from cohort studies that score what people eat against a pattern (the Mediterranean diet, the MIND diet designed for brain health, the DASH diet for blood pressure) and follow dementia over years. Randomised trials of a diet or a supplement are fewer, shorter and have had more mixed results. Nutrient studies cover vitamins, omega-3 fats, and the gut microbiome.
This page describes what published research in alzhub's library reports. It is not medical advice and does not apply to any one person: a doctor who knows the person's history is the only one who can say what a result or a treatment means for them.
What the studies report, in their own words
Whole sentences copied from the abstract or key findings of the highest-scoring matched studies, chosen because they mention the subject and give a figure. 8 of the 1,803 matched records are quoted; each links to its study page and from there to the paper.
“Eligible participants (n = 6,104, 64% female) were randomized 1:1 to a personalized schedule of online coaching in two to four modules (targeting physical activity, nutrition, cognitive activity and depression or anxiety) or a control group that received module-eligible information only.”
“Results A total of 1929 persons underwent screening, and 604 were enrolled; 301 were assigned to the MIND-diet group and 303 to the control-diet group.”
“At 6 months, all active arms (ie, arms 1 through 4) with aerobic-resistance exercise regardless of the addition of cognitive training or vitamin D, improved ADAS-Cog-13 when compared with control (mean difference, -1.79 points; 95% CI, -3.27 to -0.31 points; P = .02; d = 0.64).”
“Intervention effects were particularly due to improvements in diet (odds ratio [OR]: 1.60, 95% CI: 1.16, 2.22) and hypertension (OR: 1.61, 95% CI: 1.19, 2.18).”
“In multivariate analyses adjusted for confounders, participants allocated to a Mediterranean diet plus olive oil scored better on the RAVLT (P = .049) and Color Trail Test part 2 (P = .04) compared with controls; no between-group differences were observed for the other cognitive tests.”
“Seventeen RCTs, comprising 7214 participants, investigated the efficacy of the following drugs: Donepezil, Rivastigmine, Galantamine, Memantine, Ginkgo biloba extract (EGb), Atorvastatin-calcium and Vitamin B in the treatment of AD.”
“In the multivariable-adjusted Cox proportional hazard model, higher MIND diet score was associated with lower risk of dementia (pooled hazard ratio [HR] for every 3-point increment, 0.83; 95% CI, 0.72-0.95; P for trend = .01; I2 = 0%).”
“Only RCTs were included in this study; there were eleven studies ( n = 2609 participants) of the Mediterranean diet, seven studies ( n = 313) of the ketogenic diet and one study ( n = 37) of the MIND diet.”
What kind of evidence it is
By study design
| Design (as recorded) | Studies |
|---|---|
| Systematic review or meta-analysis | 107 |
| Randomised controlled trial | 73 |
| Other clinical trial | 5 |
| Cohort or longitudinal study | 161 |
| Case-control study | 19 |
| Cross-sectional study | 76 |
| Other recorded design | 27 |
| No design recorded | 1,335 |
The design is the one named in alzhub's record for the study; a record with none is counted as "no design recorded".
By year
| Year | Studies | Share |
|---|---|---|
| 2027 | 1 | |
| 2026 | 117 | |
| 2025 | 257 | |
| 2024 | 89 | |
| 2023 | 98 | |
| 2022 | 105 | |
| 2021 | 119 | |
| 2020 | 134 | |
| 2019 | 103 | |
| 2018 | 99 | |
| 2017 and earlier | 681 |
Other counts within the matched set
| Peer-reviewed articles | 1,755 |
| Marked open access in the record | 681 |
| Rated "high" evidence strength in alzhub's summary | 339 |
| Rated "moderate" evidence strength in alzhub's summary | 252 |
| Rated "low" evidence strength in alzhub's summary | 1,203 |
| No evidence-strength rating | 9 |
| Records stating a participant count | 511 |
| Median participants (those records) | 401 |
| Largest participant count | 574,299 |
Within the 1,803 matched studies
| Studies… | Count | Rule |
|---|---|---|
| …that name the Mediterranean, MIND or DASH diet | 391 | the abstract also contains "Mediterranean", "MIND diet" or "DASH diet" |
| …that are randomised trials | 257 | the abstract also contains "randomised" or "randomized" |
| …that mention the gut microbiome | 415 | the abstract also contains "microbiome", "microbiota" or "gut" |
The 10 highest-scoring matched studies
Title matches first, then by alzhub's usefulness score, which rates a study's design, journal, evidence and recency, not whether its result is good news.
- Alzheimer's Disease, Mild Cognitive Impairment and Mediterranean Diet. A Systematic Review and Dose-Response Meta-Analysis
- Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons
- A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial
- A phase-II randomized controlled pilot study of nicotinamide riboside supplementation in older adults with amnestic mild cognitive impairment
- Effects of Exercise Alone or Combined With Cognitive Training and Vitamin D Supplementation to Improve Cognition in Adults With Mild Cognitive Impairment: A Randomized Clinical Trial
- Facility-based and home-based multidomain interventions including cognitive training, exercise, diet, vascular risk management, and motivation for older adults: a randomized controlled feasibility trial
- Adherence to Mediterranean diet and health status: meta-analysis
- Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Trial: Genetic Resource for Precision Nutrition
- Mediterranean Diet and Age-Related Cognitive Decline: A Randomized Clinical Trial
- Association of the Mediterranean Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet With the Risk of Dementia
Systematic reviews and meta-analyses in the set
107 of the matched records are recorded as a systematic review, meta-analysis or umbrella review; the highest-scoring not already listed above:
- Comparison of multiple interventions for older adults with Alzheimer disease or mild cognitive impairment: A PRISMA-compliant network meta-analysis
- Effect of long-term pharmacological treatments on Alzheimer disease: A systematic review and network meta-analysis
- Mediterranean Diet, Ketogenic Diet or MIND Diet for Aging Populations with Cognitive Decline: A Systematic Review
- The Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet for the Aging Brain: A Systematic Review
- Dietary pattern, food, and nutritional supplement effects on cognitive outcomes in mild cognitive impairment: a systematic review of previous reviews
Newest matched studies
- Effect of Metformin on tau pathology and proteostasis in cellular and a Drosophila model of Tauopathy
- The Filamin A Proteomic Switch: Solubility States and Cytoskeletal Dynamics Explain the Inverse Epidemiological Relationship Between Cancer and Alzheimer’s Disease
- RNA-sequencing of butyrate-treated human lymphoblastoid cell lines shows dysregulated genes of multiple disease-related pathways
- Evidence that the perinatal maternal microbiome mediates metabolite signaling programs that drive sex-specific microglial metabolic alterations and Alzheimer’s disease susceptibility
- Astrocytic sEH–EET signaling regulates microglial lysosomal function and suppresses the STING–Type I interferon pathway in Alzheimer’s disease
Journals with the most matched studies
| Journal | Studies |
|---|---|
| Nutrients | 73 |
| Journal of Alzheimer's disease : JAD | 64 |
| Neurology | 41 |
| Alzheimer's & dementia : the journal of the Alzheimer's Association | 37 |
| The American journal of clinical nutrition | 27 |
Questions
- Which diet is best for preventing Alzheimer's?
- No single diet has been proven to prevent it. The Mediterranean and MIND patterns have the most cohort evidence of lower dementia rates and some trial evidence on cognition; the studies below report what each measured.
- How many studies on diet and alzheimer's does alzhub hold?
- 1,803 of the 29,380 study records in alzhub's library match the query "title or abstract mentions "Mediterranean", "MIND diet", "DASH diet", "diet"/"dietary", "nutrition"/"nutrient", "omega-3", "vitamin", "supplementation" or "microbiome/microbiota""; 870 of them name it in the title. Counted from the records when this page was built.
- What kinds of study are they?
- 107 systematic review or meta-analysis, 73 randomised controlled trials, 5 other clinical trials, 161 cohort or longitudinal studys, 19 case-control studys, 76 cross-sectional studys; 1,335 record no design.
- What is the most recent study in the set?
- "Effect of Metformin on tau pathology and proteostasis in cellular and a Drosophila model of Tauopathy" (Research Square, 2026), the newest by publication date among the matched records.
- Which journals publish most on it?
- Nutrients (73); Journal of Alzheimer's disease : JAD (64); Neurology (41), counted across the matched records.
Read on
- PreventionLifestyle trials that worked, and the ones that did not.
- Risk factors, rankedDiet among the modifiable risks.