Home › Research › Mild cognitive impairment
Risk of progression from subjective cognitive decline to mild cognitive impairment: The role of study setting
Snitz BE, Wang T, Cloonan YK, Jacobsen E, Chang CH, Hughes TF, Kamboh MI, Ganguli M.. Alzheimer's & dementia : the journal of the Alzheimer's Association, 2018-01-18
Topic: Risk, prevention and care in population studies
Introduction We compared risk of progression from subjective cognitive decline (SCD) to mild cognitive impairment (MCI) in an academic memory clinic versus a population-based study. Methods Older adults presenting at a memory clinic were classified as SCD (n = 113) or as noncomplainers (n = 82). Participants from a population study were classified as SCD (n = 592) and noncomplainers (n = 589) based on a memory complaint score. Annual follow-up performed for a mean of 3 years. Results The adjusted hazard ratio for SCD was 15.97 (95% confidence interval: 6.08-42.02, P Discussion SCD is more likely to progress to MCI in a memory clinic than the general population; participants' characteristics vary across settings. Study setting should be considered when evaluating SCD as a risk state for MCI and dementia.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Snitz, B. E., Wang, T., Cloonan, Y. K., Jacobsen, E., Chang, C. H., Hughes, T. F., et al. (2018). Risk of progression from subjective cognitive decline to mild cognitive impairment: The role of study setting. Alzheimer's & dementia : the journal of the Alzheimer's Association. https://doi.org/10.1016/j.jalz.2017.12.003
Vancouver
Snitz BE, Wang T, Cloonan YK, Jacobsen E, Chang CH, Hughes TF, et al. Risk of progression from subjective cognitive decline to mild cognitive impairment: The role of study setting. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2018. doi:10.1016/j.jalz.2017.12.003. PMID: 29352855.
BibTeX
@article{snitz2018-29352855,
author = {Snitz, B. E. and Wang, T. and Cloonan, Y. K. and Jacobsen, E. and Chang, C. H. and Hughes, T. F. and Kamboh, M. I. and Ganguli, M.},
title = {{Risk of progression from subjective cognitive decline to mild cognitive impairment: The role of study setting}},
journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
year = {2018},
doi = {10.1016/j.jalz.2017.12.003},
pmid = {29352855},
url = {https://doi.org/10.1016/j.jalz.2017.12.003}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 8 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
Key findings
- Introduction We compared risk of progression from subjective cognitive decline (SCD) to mild cognitive impairment (MCI) in an academic memory clinic versus a population-based study.
- Results The adjusted hazard ratio for SCD was 15.97 (95% confidence interval: 6.08-42.02, P Discussion SCD is more likely to progress to MCI in a memory clinic than the general population; participants' characteristics vary across settings.
Why it matters
Over about 3 years of yearly check-ups, older adults who reported memory worries (subjective cognitive decline) were more likely to move on to mild cognitive impairment if they had come to an academic memory clinic than if they were part of a general-population study. The study reports an adjusted hazard ratio of 15.97 for SCD (95% CI 6.08–42.02), but the people in each setting differed, so a risk figure from a memory clinic should not be applied to people in the wider community, or the other way round.
Study details
- Participants113
- Evidence strengthLow
How this study scored 52/100
Published in a leading specialty journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (Alzheimer's & dementia : the journal of the Alzheimer's Association) |
| Journal's citation record | 2 / 4 | Alzheimer s & Dementia: journal h-index 228 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 2 / 5 | 2018 — within 10 year(s) of the newest study here |
| Sample size | 2 / 4 | 113 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 140 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 14.0 citations a year over 10 year(s) since 2018 |
| Impact for its field and year | 4 / 6 | Cited 13.6× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 8 other studies in this library |
| Still being cited | 2 / 4 | Cited 33 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Mary Ganguli: h-index 86 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | University of Pittsburgh: institution h-index 1,470 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 29352855) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 52 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Studies this one cites
Referenced by this study and also in the alzhub library, so you can read them here. Showing 12 of 23.
Later studies that cite this one
8 studies in the alzhub library list this one in their references.
Related studies in Mild cognitive impairment
Also tagged “examination”
840 studies in the library carry the topic tag “examination”; these are this study's neighbours in a fixed, alphabetical-by-hash tour of them, not the closest in content. All 840 tagged studies.