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Consensus-Harmonized Neuropsychological Assessment for Vascular Cognitive Impairment and Dementia
Adam C. Bentvelzen, Nicole A. Kochan, Danit Saks, Russell Jude Chander, Rebecca Koncz, Stina Aam, Gilberto Sousa Alves, Emily M. Briceño et al.. JAMA Network Open, 2025-12-09
Topic: Risk, prevention and care in population studies
A total of 44 experts participated in 3 survey rounds, with 28 to 31 participants each. Consensus was reached on a core assessment battery of neuropsychological tests based on key cognitive domains, and additional guidelines for a more comprehensive test battery, cognitive screening, telehealth and computerized assessment methods, principles for normative standardization, and the assessment of diverse populations. The key cognitive domains were harmonized with the International Society for Vascular Behavioural and Cognitive Disorders version 2 World Stroke Organization (VasCog-2-WSO) diagnostic criteria for VCID. Conclusions and Relevance: This consensus statement describes the development of a harmonized neuropsychological assessment battery and guidelines for VCID (VasCog-NP) that expands on the NINDS-CSN battery with more comprehensive and flexible assessment of VCID. Harmonized with the VasCog-2-WSO diagnostic criteria, VasCog-NP could be adopted internationally to further help more consistent neuropsychological evaluations related to VCID, facilitating global comparisons for clinicians and researchers.
Key findings
- A total of 44 experts participated in 3 survey rounds, with 28 to 31 participants each.
- Consensus was reached on a core assessment battery of neuropsychological tests based on key cognitive domains, and additional guidelines for a more comprehensive test battery, cognitive screening, telehealth and computerized assessment methods, principles for normative standardization, and the assessment of diverse populations.
- The key cognitive domains were harmonized with the International Society for Vascular Behavioural and Cognitive Disorders version 2 World Stroke Organization (VasCog-2-WSO) diagnostic criteria for VCID.
- Conclusions and Relevance: This consensus statement describes the development of a harmonized neuropsychological assessment battery and guidelines for VCID (VasCog-NP) that expands on the NINDS-CSN battery with more comprehensive and flexible assessment of VCID.
- Harmonized with the VasCog-2-WSO diagnostic criteria, VasCog-NP could be adopted internationally to further help more consistent neuropsychological evaluations related to VCID, facilitating global comparisons for clinicians and researchers.
Why it matters
This consensus statement describes a harmonized neuropsychological assessment battery and guidelines for vascular cognitive impairment and dementia, developed by 44 experts. It aims to make evaluations more consistent worldwide for clinicians and researchers, not to test a treatment.
Study details
- Participants31
- Evidence strengthLow
How this study scored 51/100
Published in a leading specialty journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (JAMA Network Open) |
| Journal's citation record | 2 / 4 | JAMA Network Open: journal h-index 235 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 1 / 4 | 31 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 2 / 7 | Cited 11 times (OpenAlex, 2026-10-10) |
| Citations per year | 2 / 5 | 3.7 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 3 / 6 | Cited 7.0× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 1 / 4 | Cited 11 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author Perminder Singh Sachdev: h-index 147 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | University of Michigan: institution h-index 2,240 (OpenAlex) |
| Multi-centre collaboration | 3 / 3 | OpenAlex lists 37 institution(s) in 12 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 41364442) |
| Free to read | 2 / 2 | Free to read |
| Total | 51 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1001/jamanetworkopen.2025.47948
- PubMed: 41364442
- Original source →
- Free full text: JAMA Network Open →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Bentvelzen, A. C., Kochan, N. A., Saks, D., Chander, R. J., Koncz, R., Aam, S., et al. (2025). Consensus-Harmonized Neuropsychological Assessment for Vascular Cognitive Impairment and Dementia. JAMA Network Open. https://doi.org/10.1001/jamanetworkopen.2025.47948
Vancouver
Bentvelzen AC, Kochan NA, Saks D, Chander RJ, Koncz R, Aam S, et al. Consensus-Harmonized Neuropsychological Assessment for Vascular Cognitive Impairment and Dementia. JAMA Network Open. 2025. doi:10.1001/jamanetworkopen.2025.47948. PMID: 41364442.
BibTeX
@article{bentvelzen2025-41364442,
author = {Bentvelzen, Adam C. and Kochan, Nicole A. and Saks, Danit and Chander, Russell Jude and Koncz, Rebecca and Aam, Stina and Alves, Gilberto Sousa and Briceño, Emily M. and others},
title = {{Consensus-Harmonized Neuropsychological Assessment for Vascular Cognitive Impairment and Dementia}},
journal = {JAMA Network Open},
year = {2025},
doi = {10.1001/jamanetworkopen.2025.47948},
pmid = {41364442},
url = {https://doi.org/10.1001/jamanetworkopen.2025.47948}
}
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