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Vascular cognitive impairment and dementia
Gorelick PB, Counts SE, Nyenhuis D.. Biochimica et biophysica acta, 2015-12-15
Topic: Risk, prevention and care in population studies
Vascular contributions to cognitive impairment are receiving heightened attention as potentially modifiable factors for dementias of later life. These factors have now been linked not only to vascular cognitive disorders but also Alzheimer's disease. In this chapter we review 3 related topics that address vascular contributions to cognitive impairment: 1. vascular pathogenesis and mechanisms; 2. neuropsychological and neuroimaging phenotypic manifestations of cerebrovascular disease; and 3. prospects for prevention of cognitive impairment of later life based on cardiovascular and stroke risk modification. This article is part of a Special Issue entitled: Vascular Contributions to Cognitive Impairment and Dementia edited by M. Paul Murphy, Roderick A. Corriveau and Donna M. Wilcock.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Gorelick, P. B., Counts, S. E., & Nyenhuis, D. (2016). Vascular cognitive impairment and dementia. Biochimica et biophysica acta. https://doi.org/10.1016/j.bbadis.2015.12.015
Vancouver
Gorelick PB, Counts SE, Nyenhuis D. Vascular cognitive impairment and dementia. Biochimica et biophysica acta. 2016. doi:10.1016/j.bbadis.2015.12.015. PMID: 26704177.
BibTeX
@article{gorelick2016-26704177,
author = {Gorelick, P. B. and Counts, S. E. and Nyenhuis, D.},
title = {{Vascular cognitive impairment and dementia}},
journal = {Biochimica et biophysica acta},
year = {2016},
doi = {10.1016/j.bbadis.2015.12.015},
pmid = {26704177},
url = {https://doi.org/10.1016/j.bbadis.2015.12.015}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
Key findings
- Vascular contributions to cognitive impairment are receiving heightened attention as potentially modifiable factors for dementias of later life.
- These factors have now been linked not only to vascular cognitive disorders but also Alzheimer's disease.
- In this chapter we review 3 related topics that address vascular contributions to cognitive impairment: 1. vascular pathogenesis and mechanisms; 2. neuropsychological and neuroimaging phenotypic manifestations of cerebrovascular disease; and 3. prospects for prevention of cognitive impairment of later life based on cardiovascular and stroke risk modification.
- This article is part of a Special Issue entitled: Vascular Contributions to Cognitive Impairment and Dementia edited by M.
Why it matters
This review highlights that vascular factors contributing to cognitive impairment are potentially modifiable and have been linked not only to vascular cognitive disorders but also to Alzheimer's disease. It points to prevention of cognitive impairment in later life through modifying cardiovascular and stroke risk, but presents no new trial results.
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Study details
- Evidence strengthLow
How this study scored 42/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it. We have no data on journal's citation record, so that was left out: it earned 40 of the 96 points we could judge it on, which is 42 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Biochimica et biophysica acta) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2016 — within 20 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 184 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 15.3 citations a year over 12 year(s) since 2016 |
| Impact for its field and year | 3 / 6 | Cited 3.9× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 3 other studies in this library |
| Still being cited | 2 / 4 | Cited 43 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author David L. Nyenhuis: h-index 31 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Michigan State University: institution h-index 1,089 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 26704177) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Points | 40 / 96 | Scored on 19 of 20 parts. We have no data for the rest, so they are left out: 40 of the 96 points we could judge it on is 42 out of 100. |
| Total | 42 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1016/j.bbadis.2015.12.015
- PubMed: 26704177
- Original source →
- Free full text: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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