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This page is alzhub.org's plain-English summary of a published study, not the paper itself. It is generated from the record we hold for this study, sourced and linked below — check the original for the full text and methods.

✓ Peer-reviewed alzhub usefulness score 25 out of 100. Tau biomarkers

Topic: Amyloid, tau and blood-test diagnosis

A doença de Alzheimer (DA) configura-se como a principal causa de demência em idosos, se tornando um dos maiores desafios da medicina moderna devido à sua alta prevalência e o impacto social associado. Sendo assim, a dificuldade em reconhecer a doença de forma precoce somada à limitação dos métodos de diagnósticos tradicionais, reforça a necessidade de identificar biomarcadores mais sensíveis e acessíveis. Nesse contexto, a proteína Tau, em suas formas fosforiladas (p-tau), tem se destacado por refletir diretamente a progressão clínica e a gravidade da DA. Com isso, essa revisão integrativa analisou estudos publicados a partir de 2020 a 2025. Além disso, também foram selecionados artigos que abordam a proteína Tau como biomarcador no diagnóstico precoce e monitoramento da DA em bases de dados cientificas reconhecidas, como: PubMed, Alzheimer’s Association, Brazilian Journal of Implantology and Health Sciences e Nature. Ademais, as evidências apontam que variantes plasmáticas, como p-tau181, p-tau217 e p-tau231, além da fração BD-tau, apresentam alta eficácia diagnóstica e potencial para substituir exames mais invasivos, como a punção lombar. Ainda, observou-se que a associação entre diferentes biomarcadores amplia a precisão diagnóstica e permite prever a velocidade de progressão cognitiva. Conclui-se que, a proteína Tau representa uma ferramenta promissora para o rastreamento precoce e o acompanhamento clínico do Alzheimer, contribuindo para intervenções mais assertivas e o desenvolvimento de terapias personalizadas.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

da Silva, C. d. K. T., de Freitas, M. E. D. S., Lima, M. R. d. C., & Brito, T. G. d. S. (2025). Avaliação do Papel da Proteína Tau no Diagnóstico Precoce e Monitoramento do Alzheimer. Revista JRG de Estudos Acadêmicos. https://doi.org/10.55892/jrg.v8i19.2722

Vancouver

da Silva CdKT, de Freitas MEDS, Lima MRdC, Brito TGdS. Avaliação do Papel da Proteína Tau no Diagnóstico Precoce e Monitoramento do Alzheimer. Revista JRG de Estudos Acadêmicos. 2025. doi:10.55892/jrg.v8i19.2722.

BibTeX

@article{dasilva2025-4fb38053,
  author  = {da Silva, Camilly de Kassia Teotônio and de Freitas, Maria Eduarda Darcy Silva and Lima, Mylena Regis da Costa and Brito, Thaíse Gabriele da Silva},
  title   = {{Avaliação do Papel da Proteína Tau no Diagnóstico Precoce e Monitoramento do Alzheimer}},
  journal = {Revista JRG de Estudos Acadêmicos},
  year    = {2025},
  doi     = {10.55892/jrg.v8i19.2722},
  url     = {https://doi.org/10.55892/jrg.v8i19.2722}
}

Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.

Key findings

Why it matters

This integrative review analyzes studies on the tau protein as a biomarker for early diagnosis and monitoring of Alzheimer's disease. It is about diagnosis and monitoring, not treatment, and does not demonstrate any cure or prevention.

Study details

How this study scored 25/100
How this study's score is builtJournal tier 7 of 10; Journal's citation record 0 of 4; Study design 0 of 12; Strength of evidence 1 of 5; Peer-review validation 10 of 10; How recent 4 of 5; Sample size 0 of 4; Effect reported 0 of 3; Studied in people 0 of 3; Randomised / blinded 0 of 2; Times cited 0 of 7; Citations per year 0 of 5; Impact for its field and year 0 of 6; Cited by studies here 0 of 6; Still being cited 0 of 4; Senior author's track record 0 of 4; Institution's track record 0 of 3; Multi-centre collaboration 0 of 3; Indexed in PubMed 1 of 2; Free to read 2 of 2. Total 25 of 100.25 of 100 points earned75 not earned

Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it.

ComponentPointsWhy
Journal tier 7 / 10 Tier 3 — peer-reviewed journal (Revista JRG de Estudos Acadêmicos)
Journal's citation record 0 / 4 Revista JRG de Estudos Acadêmicos: journal h-index 5 (OpenAlex, 2026-10-29)
Study design 0 / 12 No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence 1 / 5 Rated “low” in our summary
Peer-review validation 10 / 10 Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent 4 / 5 2025 — within 3 year(s) of the newest study here
Sample size 0 / 4 Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported 0 / 3 No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people 0 / 3 Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomised / blinded 0 / 2 No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited 0 / 7 Cited 0 times (OpenAlex, 2026-10-10)
Citations per year 0 / 5 0.0 citations a year over 3 year(s) since 2025
Impact for its field and year 0 / 6 Cited 0.0× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here 0 / 6 No other study in this library cites it
Still being cited 0 / 4 Cited 0 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record 0 / 4 Last-listed author Thaíse Gabriele da Silva Brito: h-index 2 (OpenAlex, whole career)
Institution's track record 0 / 3 Faculdade Faci Wyden: institution h-index 6 (OpenAlex)
Multi-centre collaboration 0 / 3 OpenAlex lists 1 institution(s) in 0 countries — scores zero (affiliation lists can be incomplete)
Indexed in PubMed 1 / 2 Not in PubMed, but has a DOI
Free to read 2 / 2 Free to read
Total 25 / 100 —

What each of these 20 components measures, and what this score is not →

Read the original

Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).

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