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56/100

✓ Peer-reviewed alzhub usefulness score 56 out of 100. Prevention trials

Topic: Risk, prevention and care in population studies

Plain-language summary

Among the five personality domains, only extraversion was significantly associated with reduced odds of cognitive decline within the intervention group over 24 weeks (fully adjusted model: OR = 0.35; 95% CI: 0.15-0.82). These findings suggest that personality traits may be associated with cognitive stability and highlight the importance of considering personality profiles when understanding inter-individual variability in multidomain dementia prevention strategies.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Jung, J. Y., Hong, C. H., Park, Y. K., Moon, S. Y., Jeong, J. H., Park, H. K., et al. (2026). Association of the Big Five personality traits with cognitive decline: a 24-week multidomain intervention study. Frontiers in Psychiatry. https://doi.org/10.3389/fpsyt.2026.1797887

Vancouver

Jung JY, Hong CH, Park YK, Moon SY, Jeong JH, Park HK, et al. Association of the Big Five personality traits with cognitive decline: a 24-week multidomain intervention study. Frontiers in Psychiatry. 2026. doi:10.3389/fpsyt.2026.1797887. PMID: 41938858.

BibTeX

@article{jung2026-41938858,
  author  = {Jung, Jae Youn and Hong, Chang Hyung and Park, Yoo Kyoung and Moon, So Young and Jeong, Jee Hyang and Park, Hee Kyung and Choi, Seong Hye and Back, Joung Hwan and others},
  title   = {{Association of the Big Five personality traits with cognitive decline: a 24-week multidomain intervention study}},
  journal = {Frontiers in Psychiatry},
  year    = {2026},
  doi     = {10.3389/fpsyt.2026.1797887},
  pmid    = {41938858},
  url     = {https://doi.org/10.3389/fpsyt.2026.1797887}
}

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How to read this study

Design: this is a trial. Participants are assigned to a treatment or a comparison, so the key questions are who was enrolled, whether the comparison group got a placebo or nothing, how long people were followed, and whether the result is on a measure that matters to patients or on a biomarker. Open-label and small trials can overstate benefit.
Size: the record lists 136 participants. Ask whether that is enough for the question, and who they were.
Effect: the record reports “OR = 0.35”. A statistically significant result can still be small in daily life.

What the evidence grade means here

This page is graded high. alzhub.org assigns the grade automatically from keywords in the abstract, not from reading the paper. High means the abstract mentions a randomized design, a meta-analysis or a systematic review. It can add at most 5 of the 100 points in the study score, and it is a label about design, not a verdict on whether the findings are true.

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Key findings

Among the five personality domains, only extraversion was significantly associated with reduced odds of cognitive decline within the intervention group over 24 weeks (fully adjusted model: OR = 0.35; 95% CI: 0.15-0.82).
These findings suggest that personality traits may be associated with cognitive stability and highlight the importance of considering personality profiles when understanding inter-individual variability in multidomain dementia prevention strategies.

Why it matters

In this 24-week multidomain intervention study, only extraversion was associated with reduced odds of cognitive decline within the intervention group. It suggests personality may matter for prevention strategies, but it does not show that the intervention prevents dementia.

New to this subject? Start with our plain-English guide: Prevention →

Study details

Study designrandomized controlled trial
Participants136
Effect sizeOR = 0.35
Evidence strengthHigh

How this study scored 56/100

Published in a peer-reviewed journal, and it is a randomized controlled trial.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Frontiers in Psychiatry)
Journal's citation record	2 / 4	Frontiers in Psychiatry: journal h-index 194 (OpenAlex, 2026-10-29)
Study design	11 / 12	A randomized controlled trial
Strength of evidence	5 / 5	Rated “high” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	5 / 5	2026 — within 1 year(s) of the newest study here
Sample size	2 / 4	136 participants
Effect reported	3 / 3	Effect reported with a statistic (interval, p-value, ratio or similar)
Studied in people	3 / 3	Studied in people (participant count stated)
Randomized / blinded	1 / 2	Randomized (as stated in the record)
Times cited	0 / 7	Cited 0 times (OpenAlex, 2026-10-10)
Citations per year	0 / 5	0.0 citations a year over 2 year(s) since 2026
Impact for its field and year	0 / 6	Cited 0.0× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	0 / 6	No other study in this library cites it
Still being cited	0 / 4	Cited 0 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	1 / 4	Last-listed author Yong Hyuk Cho: h-index 11 (OpenAlex, whole career)
Institution's track record	0 / 3	Ewha Womans University: institution h-index 490 (OpenAlex)
Multicenter collaboration	2 / 3	OpenAlex lists 7 institution(s) in 1 country
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 41938858)
Free to read	2 / 2	Free to read
Total	56 / 100	—

What each of these 20 components measures, and what this score is not →

Read the original

Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).

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