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Alzheimer's disease as an inflammatory disease
Bolós M, Perea JR, Avila J.. Biomolecular concepts, 2017-03-01
Topic: Amyloid, tau and blood-test diagnosis
Alzheimer's disease (AD) is a neurodegenerative condition characterized by the formation of amyloid-β plaques, aggregated and hyperphosphorylated tau protein, activated microglia and neuronal cell death, ultimately leading to progressive dementia. In this short review, we focus on neuroinflammation in AD. Specifically, we describe the participation of microglia, as well as other factors that may contribute to inflammation, in neurodegeneration.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Bolós, M., Perea, JR., & Avila, J. (2017). Alzheimer's disease as an inflammatory disease. Biomolecular concepts. https://doi.org/10.1515/bmc-2016-0029
Vancouver
Bolós M, Perea JR, Avila J. Alzheimer's disease as an inflammatory disease. Biomolecular concepts. 2017. doi:10.1515/bmc-2016-0029. PMID: 28231054.
BibTeX
@article{bolos2017-28231054,
author = {Bolós, M. and Perea, JR. and Avila, J.},
title = {{Alzheimer's disease as an inflammatory disease}},
journal = {Biomolecular concepts},
year = {2017},
doi = {10.1515/bmc-2016-0029},
pmid = {28231054},
url = {https://doi.org/10.1515/bmc-2016-0029}
}
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Key findings
- In this short review, we focus on neuroinflammation in AD.
- Specifically, we describe the participation of microglia, as well as other factors that may contribute to inflammation, in neurodegeneration.
Why it matters
This short review focuses on neuroinflammation in Alzheimer's disease and the participation of microglia and other factors in neurodegeneration. It reports no treatment, cure, or prevention.
Study details
- Evidence strengthLow
How this study scored 44/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Biomolecular concepts) |
| Journal's citation record | 0 / 4 | BioMolecular Concepts: journal h-index 55 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 2 / 5 | 2017 — within 10 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 217 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 19.7 citations a year over 11 year(s) since 2017 |
| Impact for its field and year | 4 / 6 | Cited 11.1× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 3 other studies in this library |
| Still being cited | 2 / 4 | Cited 35 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author Jesús Ávila: h-index 109 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | Consejo Superior de Investigaciones Científicas: institution h-index 1,048 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 3 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 28231054) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 44 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1515/bmc-2016-0029
- PubMed: 28231054
- Original source →
- Free full text: BioMolecular Concepts →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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