31,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Participants' age ranged from 45 to 87, 53% were women, and 26% were diagnosed with dementia (39% AD, 18% Lewy Body and 17% Frontotemporal Dementia; Table 1). 5 key findings →
Design: cross-sectional Participants: 255 Evidence: moderate
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Central-northern rural communities exhibited the most pronounced high-high spatial clustering of cognitive impairment (Global Moran's I = 0.17, p < 0.001). 5 key findings →
Design: cross-sectional Participants: 18,963 Evidence: low
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Participants with impaired hearing (n = 179) were older (73.9 vs. 71.4 years, p <0.001), often male (61.5% vs. 36.5%, p <0.001), and had lower cognitive scores than normal-hearing individuals (n = 241). 5 key findings →
Design: cross-sectional Participants: 179 Evidence: low
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The prevalence of CF was 24.3%. Cerebrovascular disease (OR: 2.39, 95% CI: 1.44-3.97) and peripheral arterial disease (OR: 1.74, 95% CI: 1.03-2.95) were significant risk factors, while higher education (OR 0.85, 95% CI 0.76-0.94) and later diabetes onset (OR: 0.93, 95% CI: 0.88-0.98) were protective. 5 key findings →
Design: cross-sectional Evidence: low
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Limited data suggest nursing home (NH) Alzheimer's special care units (ASCUs) may improve care and outcomes among residents with dementia. 5 key findings →
Design: cross-sectional Participants: 13,207 Evidence: low
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The national prevalence and incidence of registered dementia diagnoses was 3.0% and 0.5%, respectively. 4 key findings →
Design: cross-sectional Evidence: low
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Ambient air pollution interacts with SVI to influence ADRD mortality rates. 3 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
[95% CI] = 0.148 [0.077-0.219]; executive function, 0.138 [0.067-0.208]; episodic memory, 0.020 [-0.051 to 0.091]; working memory, 0.128 [0.059-0.197]; visuospatial processing, 0.094 [0.023-0.164]) outperformed area-level SES in detecting cognitive deficits, and demonstrated widespread associations with poorer performance across cognitive domains. 5 key findings →
Design: cross-sectional Evidence: low
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Caregiving difficulties showed excellent reliability (α = 0.928) and yielded three components explaining 73.19% of variance. 5 key findings →
Design: cross-sectional Participants: 1,254 Evidence: low
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BackgroundDementia is a syndrome characterized by a decline in cognitive function, with Alzheimer's disease (AD) being the most common type. 3 key findings →
Design: cross-sectional Evidence: low
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The sense of food insecurity in a group of elderly people may be determined by the perception of distance to food outlets. 1 key finding →
Design: cross-sectional Evidence: low
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This study aimed to test the hypothesis that multi-level factors across the five Health Ecological Model (HEM) layers are independently associated with SCD among hypertensive patients in rural China, and to identify specific associated factors within each layer. 5 key findings →
Design: cross-sectional Evidence: moderate
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= 0.14. The effect of ADI score was also significant, β = -0.36, t = -2.30, p < .05; while the effect of RUCC, β = 0.06, t = 0.34, p = .73, and the interaction between ADI and RUCC, β = -0.001, t = 0.27, p = .99, were nonsignificant. 3 key findings →
Design: cross-sectional Participants: 114 Evidence: low
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Lower objective SES was associated with poorer performance on all cognitive domains: episodic memory (β = 0.115, p = 0.003), executive function (β = 0.210, p 0.05). 5 key findings →
Design: cross-sectional Evidence: high
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Higher ADI was significantly associated with increased CRP (r=0.469, p = 0.002) and TREM-1 (r=0.316, p = 0.047). 5 key findings →
Design: cross-sectional Participants: 40 Evidence: moderate
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Loneliness moderated the relationship between national ADI scores and short-term visuospatial memory. 5 key findings →
Design: cross-sectional Participants: 136 Evidence: low
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Older adults with Alzheimer's disease (AD) frequently present to emergency departments (EDs) with multiple coexisting conditions. 5 key findings →
Design: cross-sectional Participants: 125,461 Evidence: moderate
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Bivariate analyses showed that chain grocery store shoppers reported significantly greater fruit and vegetable intake (2.42 vs. 2.14 times/day for independent grocery store shoppers, p < 0.001) and lower rates of food insecurity compared to independent store shoppers (45.9% vs. 65.3% for independent grocery store shoppers, p < 0.001). 5 key findings →
Design: cross-sectional Evidence: low
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Significant regional differences in AD dementia prevalence were observed (F = 126.56, p < 0.05). 2 key findings →
Design: cross-sectional Evidence: low
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A total of 11 case reports met criteria for inclusion. 5 key findings →
Design: cross-sectional Participants: 56 Evidence: low
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Agricultural pesticide use represents one of the most geographically patterned environmental systems, yet most prior research has focused largely on individual compounds rather than correlated exposure regimes. 3 key findings →
Design: cross-sectional Evidence: moderate
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Black Americans a have higher risk of cognitive impairment relative to other racial/ethnic groups, and Black women have the highest prevalence of Alzheimer's disease and related dementias; however, the mechanisms underlying cognitive impairment are poorly understood. 4 key findings →
Design: cross-sectional Evidence: moderate
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Diagnostic classifications, mean age, and education did not differ significantly across classifications. 5 key findings →
Design: cross-sectional Evidence: moderate
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Counties had a mean prevalence of 65.3 per 1,000 (SD 15.5) for highly likely ADRD and 123.5 per 1,000 (SD 27.0) for all determinations. 5 key findings →
Design: cross-sectional Participants: 3,108 Evidence: low
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Participants were 68.7±9.3 years old; 70% were female; 8% identified as Black, 89% White, as 3% other racial group; and 14% identified as Hispanic. 5 key findings →
Design: cross-sectional Participants: 161 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 31,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 31,380 records, built mostly from automated pulls of Europe PMC (65.6% of the library) and OpenAlex (16.2%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,048 records (3.3% of the library) are not peer-reviewed — 973 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →
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